Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   LLA22_RS03385 Genome accession   NZ_CP128421
Coordinates   655151..655750 (-) Length   199 a.a.
NCBI ID   WP_011834647.1    Uniprot ID   A0A166TF89
Organism   Lactococcus cremoris strain A.2.2     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 650151..660750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLA22_RS03375 (LLA22_03375) acnA 651307..653853 (+) 2547 WP_015082159.1 aconitate hydratase AcnA -
  LLA22_RS03380 (LLA22_03380) icd 653873..655111 (+) 1239 WP_015082160.1 NADP-dependent isocitrate dehydrogenase -
  LLA22_RS03385 (LLA22_03385) clpP 655151..655750 (-) 600 WP_011834647.1 ATP-dependent Clp protease proteolytic subunit Regulator
  LLA22_RS03390 (LLA22_03390) - 655945..656475 (+) 531 WP_011675638.1 hypothetical protein -
  LLA22_RS03395 (LLA22_03395) spx 656645..657043 (+) 399 WP_396418546.1 transcriptional regulator Spx -
  LLA22_RS03400 (LLA22_03400) - 657194..657328 (-) 135 WP_014572996.1 hypothetical protein -
  LLA22_RS03405 (LLA22_03405) - 657425..658588 (-) 1164 WP_011675640.1 ABC transporter permease -

Sequence

Protein


Download         Length: 199 a.a.        Molecular weight: 22052.21 Da        Isoelectric Point: 4.7423

>NTDB_id=847416 LLA22_RS03385 WP_011834647.1 655151..655750(-) (clpP) [Lactococcus cremoris strain A.2.2]
MGYLVPTVIEQSSRGERAYDIYSRLLKDRIIMLTGPVEDGMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVD
TMNFIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYLIHQPMGGAGQGTQQTDMAIVAEQLLKTRKRLEQILADN
SNRSLEQIHKDAERDHWMDAKETLEYGFIDEIMENNSLK

Nucleotide


Download         Length: 600 bp        

>NTDB_id=847416 LLA22_RS03385 WP_011834647.1 655151..655750(-) (clpP) [Lactococcus cremoris strain A.2.2]
ATGGGTTATTTAGTACCTACCGTTATTGAACAATCAAGCCGTGGTGAACGTGCTTATGATATTTATTCACGACTTTTAAA
AGACCGTATTATCATGCTGACAGGACCTGTTGAAGATGGTATGGCAAATTCTATCATTGCCCAACTTCTTTTCTTGGATG
CACAAGATAATACTAAAGACATTTATCTCTATGTAAACACCCCTGGTGGTTCTGTATCAGCTGGGCTCGCTATCGTGGAT
ACAATGAACTTTATCAAATCGGATGTCCAAACTATCGTTATGGGAATGGCTGCTTCTATGGGAACAATCATCGCCTCAAG
CGGTACTAAGGGTAAACGATTCATGTTACCAAATGCTGAATACCTCATTCACCAACCAATGGGTGGTGCAGGTCAAGGTA
CTCAACAAACTGATATGGCAATCGTCGCCGAACAACTTTTGAAAACACGTAAACGTTTGGAACAAATCCTTGCTGATAAT
TCTAATCGCTCACTTGAACAAATTCACAAAGATGCTGAACGTGACCATTGGATGGATGCCAAAGAAACTTTAGAATATGG
TTTCATTGATGAAATTATGGAAAATAATTCATTAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A166TF89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Lactococcus lactis subsp. cremoris KW2

100

100

1
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

99.497

100

0.995
  clpP Streptococcus mutans UA159

87.245

98.492

0.859
  clpP Streptococcus thermophilus LMD-9

86.735

98.492

0.854
  clpP Streptococcus thermophilus LMG 18311

86.735

98.492

0.854
  clpP Streptococcus pyogenes MGAS315

85.714

98.492

0.844
  clpP Streptococcus pyogenes JRS4

85.714

98.492

0.844
  clpP Streptococcus pneumoniae D39

84.615

97.99

0.829
  clpP Streptococcus pneumoniae TIGR4

84.615

97.99

0.829
  clpP Streptococcus pneumoniae R6

84.615

97.99

0.829
  clpP Streptococcus pneumoniae Rx1

84.615

97.99

0.829
  clpP Bacillus subtilis subsp. subtilis str. 168

57.895

95.477

0.553
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.995

96.985

0.553