Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QQ988_RS04585 Genome accession   NZ_CP127869
Coordinates   968735..969364 (+) Length   209 a.a.
NCBI ID   WP_002473914.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain NG02     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 963735..974364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQ988_RS04555 (QQ988_04555) - 963840..964376 (+) 537 WP_002494124.1 hypothetical protein -
  QQ988_RS04560 (QQ988_04560) - 964527..965513 (-) 987 WP_002494125.1 aromatic acid exporter family protein -
  QQ988_RS04565 (QQ988_04565) map 965687..966442 (+) 756 WP_193620699.1 type I methionyl aminopeptidase -
  QQ988_RS04570 (QQ988_04570) - 966600..966986 (+) 387 WP_001830382.1 hypothetical protein -
  QQ988_RS04575 (QQ988_04575) liaF 967001..967702 (+) 702 WP_286097108.1 cell wall-active antibiotics response protein LiaF -
  QQ988_RS04580 (QQ988_04580) vraS 967699..968745 (+) 1047 WP_001830374.1 sensor histidine kinase Regulator
  QQ988_RS04585 (QQ988_04585) vraR 968735..969364 (+) 630 WP_002473914.1 two-component system response regulator VraR Regulator
  QQ988_RS04590 (QQ988_04590) - 969421..970599 (-) 1179 WP_001830411.1 YihY/virulence factor BrkB family protein -
  QQ988_RS04595 (QQ988_04595) - 971006..971290 (-) 285 WP_002473916.1 YtxH domain-containing protein -
  QQ988_RS04600 (QQ988_04600) - 971298..971762 (-) 465 WP_002498659.1 low molecular weight protein-tyrosine-phosphatase -
  QQ988_RS04605 (QQ988_04605) - 971903..972118 (+) 216 WP_001830421.1 DUF1128 domain-containing protein -
  QQ988_RS04610 (QQ988_04610) - 972120..973361 (+) 1242 WP_017465013.1 aminopeptidase -
  QQ988_RS04615 (QQ988_04615) - 973441..973971 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23598.22 Da        Isoelectric Point: 4.7218

>NTDB_id=844903 QQ988_RS04585 WP_002473914.1 968735..969364(+) (vraR) [Staphylococcus epidermidis strain NG02]
MAIKVLFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=844903 QQ988_RS04585 WP_002473914.1 968735..969364(+) (vraR) [Staphylococcus epidermidis strain NG02]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACTCAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAAGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCAACTACTGAAATTAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAGGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCCTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTTCAAGATCGAACACAAGCAGTAATCTATGCGTTCCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

95.215

100

0.952
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373