Detailed information NTG0842838

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: QRX25_RS16790
• Genome accession: NZ_CP127224
• Coordinates: 3265830..3266426 (+)
• Length: 198 a.a.
• NCBI ID: WP_003151513.1
• Uniprot ID: I2CAH7
• Organism: Bacillus sp. L381
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3260830..3271426

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QRX25_RS16765 (QRX25_16760)	-	3260875..3261186 (+)	312	WP_088613509.1	hypothetical protein	-
QRX25_RS16775 (QRX25_16770)	-	3261497..3262966 (-)	1470	WP_212099427.1	glycoside hydrolase family 32 protein	-
QRX25_RS16780 (QRX25_16775)	-	3262959..3264212 (-)	1254	WP_212101777.1	MFS transporter	-
QRX25_RS16785 (QRX25_16780)	-	3264583..3265557 (+)	975	WP_212099429.1	LacI family DNA-binding transcriptional regulator	-
QRX25_RS16790 (QRX25_16785)	clpP	3265830..3266426 (+)	597	WP_003151513.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
QRX25_RS16795 (QRX25_16790)	-	3266468..3266788 (-)	321	Protein_3245	LysR substrate-binding domain-containing protein	-
QRX25_RS16800 (QRX25_16795)	-	3267404..3267979 (-)	576	WP_013353716.1	TIGR00730 family Rossman fold protein	-
QRX25_RS16805 (QRX25_16800)	-	3268095..3268415 (+)	321	WP_065982407.1	MazG-like family protein	-
QRX25_RS16810 (QRX25_16805)	-	3268461..3270050 (-)	1590	WP_065982928.1	SulP family inorganic anion transporter	-
QRX25_RS16815 (QRX25_16810)	-	3270053..3270643 (-)	591	WP_088030702.1	carbonic anhydrase	-
QRX25_RS16820 (QRX25_16815)	-	3270716..3270988 (+)	273	WP_258415385.1	hypothetical protein	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21831.06 Da
• Isoelectric Point: 4.6982

>NTDB_id=842838 QRX25_RS16790 WP_003151513.1 3265830..3266426(+) (clpP) [Bacillus sp. L381]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSADEALEYGLIDKVLTRNTEDQK

Nucleotide

• Length: 597 bp

>NTDB_id=842838 QRX25_RS16790 WP_003151513.1 3265830..3266426(+) (clpP) [Bacillus sp. L381]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGAGAAAGAGCTTATGACATTTACTCCCGTCTTTTGAAGGA
CCGTATTATCATGCTTGGATCTGCGATTGATGACAACGTTGCAAACTCCATCGTGTCACAGCTTTTATTCCTTGAAGCGG
AAGACCCTGAAAAAGATATTTCCATTTACATTAACAGCCCTGGCGGATCAATCACTGCCGGTATGGCAATCTATGATACA
ATGCAGTTCATTAAACCGAAAGTATCCACGATCTGCATCGGTATGGCCGCTTCTATGGGAGCATTCTTACTTGCTGCCGG
AGAAAAAGGCAAACGTTACGCGCTTCCTAACAGTGAAGTCATGATTCACCAGCCGCTTGGCGGAGCGCAAGGACAGGCGA
CTGAAATTGAAATCGCGGCTAAACGCATTCTCTTGCTTCGTGATAAATTAAACAAAGTGCTTGCTGAACGTACCGGCCAG
CCGCTTGAAGTGATCGAGCGCGACACGGACCGCGACAACTTCAAATCAGCTGATGAAGCTTTAGAATACGGCTTAATCGA
TAAAGTGCTGACACGCAATACGGAAGACCAGAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: I2CAH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	95.96	100	0.96
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.586	96.465	0.662
clpP	Streptococcus thermophilus LMG 18311	58.549	97.475	0.571
clpP	Streptococcus thermophilus LMD-9	58.549	97.475	0.571
clpP	Streptococcus pneumoniae D39	57.216	97.98	0.561
clpP	Streptococcus pneumoniae Rx1	57.216	97.98	0.561
clpP	Streptococcus pneumoniae R6	57.216	97.98	0.561
clpP	Streptococcus pneumoniae TIGR4	57.216	97.98	0.561
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	97.98	0.556
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.639	97.98	0.535
clpP	Streptococcus mutans UA159	54.639	97.98	0.535