Detailed information NTG0084119

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LLC_RS00835
• Genome accession: NZ_AP024222
• Coordinates: 163364..164212 (-)
• Length: 282 a.a.
• NCBI ID: WP_061777906.1
• Uniprot ID: A0AAD1NHF5
• Organism: Lactococcus cremoris strain EPSC
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 158364..169212

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLC_RS00820 (LLC_01690)	xerS	158434..159504 (+)	1071	WP_014572599.1	tyrosine recombinase XerS	-
LLC_RS00825 (LLC_01700)	trmFO	159554..160900 (-)	1347	WP_032950090.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
LLC_RS00830 (LLC_01710)	topA	160972..163098 (-)	2127	WP_015082465.1	type I DNA topoisomerase	-
LLC_RS00835 (LLC_01720)	dprA	163364..164212 (-)	849	WP_061777906.1	DNA-processing protein DprA	Machinery gene
LLC_RS00840 (LLC_01730)	-	164360..164740 (-)	381	WP_061777905.1	RidA family protein	-
LLC_RS00845 (LLC_01740)	budA	164780..165490 (-)	711	WP_011676302.1	acetolactate decarboxylase	-
LLC_RS00850 (LLC_01750)	ilvA	165625..166875 (-)	1251	WP_061777904.1	threonine ammonia-lyase IlvA	-
LLC_RS00855 (LLC_01760)	ilvC	166934..167956 (-)	1023	WP_061777903.1	ketol-acid reductoisomerase	-
LLC_RS00860 (LLC_01770)	ilvN	168002..168478 (-)	477	WP_021037263.1	acetolactate synthase small subunit	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31827.94 Da
• Isoelectric Point: 9.8386

>NTDB_id=84119 LLC_RS00835 WP_061777906.1 163364..164212(-) (dprA) [Lactococcus cremoris strain EPSC]
MITNFDLFRWKKAGMTNLGVNKLLKFFRKYDIKISLRQMGQVAQVKSIPNFIEQYKNQDVKKLRIDYKKFSSFSILDDLY
PERLREIYNPPVLIFYQGNIDLLKNPKLAFVGSRLAGQSGIKAVQKIITELNQSFTIVSGLAKGIDTASHLSAIKTKTPT
IAVIGTGLDIFYPLENSKIQEYLAKNQLVLSEYSLGEKPLKYHFPERNRIIAGLSRGVVVVEAKLRSGSLITCERALEEG
RDIFAIPGNIADGTSDGCNHLIQQGAKLVYQAQDILEEYLYN

Nucleotide

• Length: 849 bp

>NTDB_id=84119 LLC_RS00835 WP_061777906.1 163364..164212(-) (dprA) [Lactococcus cremoris strain EPSC]
ATGATTACAAATTTTGATTTATTTCGTTGGAAAAAAGCAGGAATGACCAATCTTGGTGTAAATAAGCTCTTAAAATTTTT
CCGCAAATATGATATAAAAATAAGCTTACGACAAATGGGACAAGTGGCTCAAGTCAAATCAATCCCTAACTTTATCGAAC
AATATAAAAATCAGGACGTAAAGAAACTCAGGATAGACTATAAAAAATTTTCCTCCTTTTCCATTCTTGATGACCTTTAT
CCCGAGCGTCTAAGAGAAATCTACAACCCACCCGTTTTAATTTTTTATCAGGGAAATATTGATTTATTAAAAAATCCTAA
ACTTGCCTTTGTTGGAAGCCGCCTAGCAGGTCAATCAGGGATAAAAGCTGTCCAAAAAATTATCACAGAATTGAATCAAT
CCTTTACAATAGTAAGCGGGCTTGCTAAAGGGATTGACACAGCCAGCCATCTGTCAGCAATTAAAACTAAAACACCAACA
ATTGCTGTTATTGGTACAGGATTGGATATTTTCTATCCACTAGAAAATAGTAAAATACAGGAATATCTAGCAAAAAATCA
ATTAGTTTTAAGTGAATATTCATTAGGCGAAAAACCACTTAAATACCACTTTCCAGAGCGCAATCGAATTATTGCTGGTC
TTTCACGGGGAGTTGTTGTCGTGGAAGCAAAATTAAGAAGTGGCAGTTTAATCACCTGTGAAAGGGCACTGGAAGAAGGA
AGAGATATCTTTGCCATCCCTGGAAATATTGCAGATGGAACATCTGATGGCTGTAATCATCTTATTCAACAAGGAGCAAA
ACTTGTCTATCAAGCTCAAGATATTTTAGAAGAATATTTGTACAATTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (69-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (2-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Lactococcus lactis subsp. cremoris KW2	97.872	100	0.979
dprA	Streptococcus mutans UA159	58.993	98.582	0.582
dprA/cilB/dalA	Streptococcus mitis SK321	56.071	99.291	0.557
dprA/cilB/dalA	Streptococcus pneumoniae R6	55.714	99.291	0.553
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	55.714	99.291	0.553
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	55.714	99.291	0.553
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	55.714	99.291	0.553
dprA/cilB/dalA	Streptococcus pneumoniae D39	55.714	99.291	0.553
dprA	Bacillus subtilis subsp. subtilis str. 168	39.273	97.518	0.383
dprA	Legionella pneumophila strain ERS1305867	39.13	97.872	0.383
dprA	Vibrio campbellii strain DS40M4	35.314	100	0.379
dprA	Haemophilus influenzae Rd KW20	39.63	95.745	0.379