Detailed information NTG0838029

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: LL303_RS08670
• Genome accession: NZ_CP126467
• Coordinates: 1701766..1702458 (-)
• Length: 230 a.a.
• NCBI ID: WP_095348499.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain 303
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1696766..1707458

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL303_RS08655 (LL303_08635)	-	1698385..1698726 (-)	342	WP_010906046.1	P-II family nitrogen regulator	-
LL303_RS08660 (LL303_08640)	-	1698858..1700099 (-)	1242	WP_023164351.1	ammonium transporter	-
LL303_RS08665 (LL303_08645)	covS	1700282..1701757 (-)	1476	WP_023164352.1	HAMP domain-containing histidine kinase	Regulator
LL303_RS08670 (LL303_08650)	covR	1701766..1702458 (-)	693	WP_095348499.1	response regulator transcription factor	Regulator
LL303_RS08675 (LL303_08655)	-	1702614..1703144 (-)	531	WP_023164353.1	DUF177 domain-containing protein	-
LL303_RS08680 (LL303_08660)	-	1703275..1703520 (-)	246	WP_003130760.1	type B 50S ribosomal protein L31	-
LL303_RS08685 (LL303_08665)	-	1703676..1704140 (-)	465	WP_003130761.1	hypothetical protein	-
LL303_RS08690 (LL303_08670)	-	1704221..1704583 (-)	363	WP_010906050.1	TIGR02328 family protein	-
LL303_RS08695 (LL303_08675)	-	1704934..1705065 (-)	132	WP_021722678.1	hypothetical protein	-
LL303_RS08700 (LL303_08680)	-	1705069..1705566 (-)	498	WP_249357244.1	CHAP domain-containing protein	-
LL303_RS08705 (LL303_08685)	-	1705660..1706496 (-)	837	WP_023164354.1	metallophosphoesterase	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26710.40 Da
• Isoelectric Point: 5.0076

>NTDB_id=838029 LL303_RS08670 WP_095348499.1 1701766..1702458(-) (covR) [Lactococcus lactis subsp. lactis strain 303]
MTSKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEATSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREYLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide

• Length: 693 bp

>NTDB_id=838029 LL303_RS08670 WP_095348499.1 1701766..1702458(-) (covR) [Lactococcus lactis subsp. lactis strain 303]
ATGACTTCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCGCGATTCGTCTCATTAGAATTAGAACATGAAGG
CTATGCGACTGAGATTAAAGATAATGGTCGTTCTGGTCTTGAAGAAGCAACTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGACGGTTTTGAGGTAGCCCGTCGTTTACGAAAAGAAAAAGATACACCAATCATTATGATG
ACGGCACGTGATTCAACGATGGACCGTGTTGCTGGTCTTGATATTGGGGCTGATGATTATATCACTAAACCTTTTGCGAT
TGAGGAACTTTTGGCGCGTGTTCGTGCTTTCTTCCGTCGTGAAGAGCATGGTCATGCCGTTGAACGTGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGACAAAACGAATCGCACCGTTCATCGTGGTAAAAAAGTAATTGATTTAACACGTCGTGAG
TATGACCTCCTTTTGACATTGATGCAAAATGTTGGCGATGTTGTGACTCGTGAATATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTGGATGTTTATATCCGTTATCTTAGAAATAAAATTGATGTTGAAGGTCAAGATA
GCTATATTCAAACTGTTCGTGGCTTAGGTTATGTAATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-115)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (153-226)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Lactococcus lactis subsp. lactis strain DGCC12653	99.565	100	0.996
covR	Streptococcus salivarius strain HSISS4	68.421	99.13	0.678
vicR	Streptococcus mutans UA159	45.455	100	0.457
micA	Streptococcus pneumoniae Cp1015	43.043	100	0.43
ciaR	Streptococcus mutans UA159	37.611	98.261	0.37
ciaR	Streptococcus pneumoniae Rx1	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae D39	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae R6	36.726	98.261	0.361
ciaR	Streptococcus pneumoniae TIGR4	36.726	98.261	0.361