Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R8568_RS10025 Genome accession   NZ_AP026931
Coordinates   1944840..1945244 (-) Length   134 a.a.
NCBI ID   WP_224781436.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701541     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1939840..1950244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8568_RS09995 (PC1520_19330) - 1940149..1941024 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  R8568_RS10000 (PC1520_19340) pstC 1941142..1942005 (+) 864 WP_000165892.1 phosphate ABC transporter permease subunit PstC -
  R8568_RS10005 (PC1520_19350) pstA 1941998..1942813 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  R8568_RS10010 (PC1520_19360) pstB 1942815..1943567 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  R8568_RS10015 (PC1520_19370) phoU 1943582..1944232 (+) 651 WP_001245783.1 phosphate signaling complex protein PhoU -
  R8568_RS10020 (PC1520_19380) - 1944273..1944725 (+) 453 Protein_1934 transposase -
  R8568_RS10025 (PC1520_19390) comR 1944840..1945244 (-) 405 WP_224781436.1 helix-turn-helix transcriptional regulator Regulator
  R8568_RS10030 (PC1520_19400) - 1945492..1946508 (+) 1017 WP_000415107.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  R8568_RS10035 (PC1520_19410) galU 1946530..1947429 (+) 900 WP_000202226.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  R8568_RS10040 (PC1520_19420) - 1947496..1948173 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  R8568_RS10045 (PC1520_19430) - 1948157..1948696 (-) 540 WP_000834342.1 5-formyltetrahydrofolate cyclo-ligase -
  R8568_RS10050 (PC1520_19440) - 1948708..1949838 (-) 1131 WP_000885069.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 16231.64 Da        Isoelectric Point: 4.5242

>NTDB_id=83455 R8568_RS10025 WP_224781436.1 1944840..1945244(-) (comR) [Streptococcus pneumoniae strain PZ900701541]
MAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETI
AQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 405 bp        

>NTDB_id=83455 R8568_RS10025 WP_224781436.1 1944840..1945244(-) (comR) [Streptococcus pneumoniae strain PZ900701541]
TTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAA
TGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAA
GTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATC
GCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCAT
CCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCT
GGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(60-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.63

80.597

0.44
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

54.717

79.104

0.433
  comR Streptococcus pyogenes MGAS315

52.778

80.597

0.425
  comR Streptococcus mutans UA159

50

80.597

0.403
  comR Streptococcus suis 05ZYH33

47.17

79.104

0.373
  comR Streptococcus suis P1/7

47.17

79.104

0.373
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

48.039

76.119

0.366
  comR Streptococcus suis D9

46.226

79.104

0.366