Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R8623_RS10015 Genome accession   NZ_AP026928
Coordinates   1924303..1924707 (-) Length   134 a.a.
NCBI ID   WP_224781436.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700406     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1919303..1929707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8623_RS09985 (PC0401_19120) - 1919612..1920487 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  R8623_RS09990 (PC0401_19130) pstC 1920605..1921468 (+) 864 WP_000165892.1 phosphate ABC transporter permease subunit PstC -
  R8623_RS09995 (PC0401_19140) pstA 1921461..1922276 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  R8623_RS10000 (PC0401_19150) pstB 1922278..1923030 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  R8623_RS10005 (PC0401_19160) phoU 1923045..1923695 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  R8623_RS10010 (PC0401_19170) - 1923736..1924188 (+) 453 Protein_1930 transposase -
  R8623_RS10015 (PC0401_19180) comR 1924303..1924707 (-) 405 WP_224781436.1 helix-turn-helix transcriptional regulator Regulator
  R8623_RS10020 (PC0401_19190) - 1924955..1925971 (+) 1017 WP_000415103.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  R8623_RS10025 (PC0401_19200) galU 1925993..1926892 (+) 900 WP_024477964.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  R8623_RS10030 (PC0401_19210) - 1926959..1927636 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  R8623_RS10035 (PC0401_19220) - 1927620..1928159 (-) 540 WP_024477965.1 5-formyltetrahydrofolate cyclo-ligase -
  R8623_RS10040 (PC0401_19230) - 1928171..1929301 (-) 1131 WP_000885066.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 16231.64 Da        Isoelectric Point: 4.5242

>NTDB_id=83103 R8623_RS10015 WP_224781436.1 1924303..1924707(-) (comR) [Streptococcus pneumoniae strain PZ900700406]
MAKKISRSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETI
AQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 405 bp        

>NTDB_id=83103 R8623_RS10015 WP_224781436.1 1924303..1924707(-) (comR) [Streptococcus pneumoniae strain PZ900700406]
TTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAA
TGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAA
GTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACATACGAAGATGAAACTATC
GCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTATTATGATAGGCTACCTGAGGAAGAAAGATTTATCAT
CCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCT
GGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(60-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.63

80.597

0.44
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

54.717

79.104

0.433
  comR Streptococcus pyogenes MGAS315

52.778

80.597

0.425
  comR Streptococcus mutans UA159

50

80.597

0.403
  comR Streptococcus suis 05ZYH33

47.17

79.104

0.373
  comR Streptococcus suis P1/7

47.17

79.104

0.373
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

48.039

76.119

0.366
  comR Streptococcus suis D9

46.226

79.104

0.366

Multiple sequence alignment