Detailed information NTG0082803

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: H7675_RS07375
• Genome accession: NZ_AP023389
• Coordinates: 1476895..1477485 (-)
• Length: 196 a.a.
• NCBI ID: WP_002985850.1
• Uniprot ID: A0A9X8T4H8
• Organism: Streptococcus pyogenes strain KUN-0012590
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1471895..1482485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7675_RS07340 (KUN2590_14050)	-	1472076..1472468 (-)	393	WP_002985833.1	DUF5684 domain-containing protein	-
H7675_RS07345 (KUN2590_14060)	rsmI	1472495..1473358 (-)	864	WP_021733048.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
H7675_RS07350 (KUN2590_14070)	yabA	1473363..1473686 (-)	324	WP_053308587.1	DNA replication initiation control protein YabA	-
H7675_RS09370	-	1474090..1474224 (-)	135	WP_014635307.1	tpl protein	-
H7675_RS07360 (KUN2590_14080)	-	1474349..1475224 (-)	876	WP_011528291.1	DNA polymerase III subunit delta'	-
H7675_RS07365 (KUN2590_14090)	tmk	1475242..1475877 (-)	636	WP_014635306.1	dTMP kinase	-
H7675_RS07370 (KUN2590_14100)	-	1476125..1476400 (-)	276	WP_002985847.1	YlbG family protein	-
H7675_RS07375 (KUN2590_14110)	clpP	1476895..1477485 (-)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
H7675_RS07380 (KUN2590_14120)	upp	1477709..1478338 (-)	630	WP_002985854.1	uracil phosphoribosyltransferase	-
H7675_RS07385 (KUN2590_14130)	-	1478506..1480140 (-)	1635	WP_136285967.1	polysaccharide biosynthesis protein	-
H7675_RS07390 (KUN2590_14140)	-	1480228..1481673 (+)	1446	WP_136285968.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21648.88 Da
• Isoelectric Point: 5.2834

>NTDB_id=82803 H7675_RS07375 WP_002985850.1 1476895..1477485(-) (clpP) [Streptococcus pyogenes strain KUN-0012590]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=82803 H7675_RS07375 WP_002985850.1 1476895..1477485(-) (clpP) [Streptococcus pyogenes strain KUN-0012590]
ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACGAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCACAAAATGCTGGAAAA
ACGATTAAACAAATTCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561