Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R8635_RS10770 Genome accession   NZ_AP026924
Coordinates   2056321..2056761 (-) Length   146 a.a.
NCBI ID   WP_317657544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2051321..2061761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS10740 (PC0062_20850) - 2051623..2052498 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  R8635_RS10745 (PC0062_20860) pstC 2052616..2053479 (+) 864 WP_000595180.1 phosphate ABC transporter permease subunit PstC -
  R8635_RS10750 (PC0062_20870) pstA 2053472..2054287 (+) 816 WP_000049768.1 phosphate ABC transporter permease PstA -
  R8635_RS10755 (PC0062_20880) pstB 2054289..2055041 (+) 753 WP_000536450.1 phosphate ABC transporter ATP-binding protein PstB -
  R8635_RS10760 (PC0062_20890) phoU 2055056..2055706 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  R8635_RS10765 (PC0062_20900) - 2055755..2056198 (+) 444 Protein_2087 transposase -
  R8635_RS10770 (PC0062_20910) comR 2056321..2056761 (-) 441 WP_317657544.1 XRE family transcriptional regulator Regulator
  R8635_RS10775 (PC0062_20920) - 2056973..2057989 (+) 1017 WP_000415110.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  R8635_RS10780 (PC0062_20930) galU 2058011..2058910 (+) 900 WP_000202228.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  R8635_RS10785 (PC0062_20940) - 2058977..2059654 (-) 678 WP_000658498.1 rhomboid family intramembrane serine protease -
  R8635_RS10790 (PC0062_20950) - 2059638..2060177 (-) 540 WP_000834308.1 5-formyltetrahydrofolate cyclo-ligase -
  R8635_RS10795 (PC0062_20960) - 2060189..2061319 (-) 1131 WP_000885068.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17709.41 Da        Isoelectric Point: 4.8630

>NTDB_id=82616 R8635_RS10770 WP_317657544.1 2056321..2056761(-) (comR) [Streptococcus pneumoniae strain PZ900700063]
MREFGEKIKRLRLAKKISHSEFCGDESELSIRQLIRIENGESRPILTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYF
LMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 441 bp        

>NTDB_id=82616 R8635_RS10770 WP_317657544.1 2056321..2056761(-) (comR) [Streptococcus pneumoniae strain PZ900700063]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCATTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAATACTAACAAAGTTAAAATATATTGCTG
AACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTC
TTGATGAGGACTCCTACATACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAGTA
TTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTAGCACTAGCGAACTACACAGTTCAAA
AATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(72-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.167

82.192

0.445
  comR Streptococcus pyogenes MGAS315

52.5

82.192

0.432
  comR Streptococcus mutans UA159

51.667

82.192

0.425
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

52.727

75.342

0.397
  comR Streptococcus suis P1/7

45.763

80.822

0.37
  comR Streptococcus suis 05ZYH33

45.763

80.822

0.37
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

46.491

78.082

0.363
  comR Streptococcus suis D9

44.915

80.822

0.363

Multiple sequence alignment