Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R8625_RS10185 Genome accession   NZ_AP026923
Coordinates   1934729..1935169 (-) Length   146 a.a.
NCBI ID   WP_001206586.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1929729..1940169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS10155 (PC0054_19610) - 1930038..1930913 (+) 876 WP_000669493.1 substrate-binding domain-containing protein -
  R8625_RS10160 (PC0054_19620) pstC 1931031..1931894 (+) 864 WP_000165893.1 phosphate ABC transporter permease subunit PstC -
  R8625_RS10165 (PC0054_19630) pstA 1931887..1932702 (+) 816 WP_317649179.1 phosphate ABC transporter permease PstA -
  R8625_RS10170 (PC0054_19640) pstB 1932704..1933456 (+) 753 WP_000536449.1 phosphate ABC transporter ATP-binding protein PstB -
  R8625_RS10175 (PC0054_19650) phoU 1933471..1934121 (+) 651 WP_001245781.1 phosphate signaling complex protein PhoU -
  R8625_RS10180 (PC0054_19660) - 1934162..1934614 (+) 453 Protein_1961 transposase -
  R8625_RS10185 (PC0054_19670) comR 1934729..1935169 (-) 441 WP_001206586.1 helix-turn-helix transcriptional regulator Regulator
  R8625_RS10190 (PC0054_19680) - 1935381..1936397 (+) 1017 WP_000415102.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  R8625_RS10195 (PC0054_19690) galU 1936419..1937318 (+) 900 WP_000202227.1 UTP--glucose-1-phosphate uridylyltransferase GalU -
  R8625_RS10200 (PC0054_19700) - 1937385..1938062 (-) 678 WP_050223439.1 rhomboid family intramembrane serine protease -
  R8625_RS10205 (PC0054_19710) - 1938046..1938585 (-) 540 WP_130894711.1 5-formyltetrahydrofolate cyclo-ligase -
  R8625_RS10210 (PC0054_19720) - 1938597..1939727 (-) 1131 WP_130894712.1 N-acetyldiaminopimelate deacetylase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17630.36 Da        Isoelectric Point: 5.1703

>NTDB_id=82491 R8625_RS10185 WP_001206586.1 1934729..1935169(-) (comR) [Streptococcus pneumoniae strain PZ900700054]
MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYF
LMRTPTYEDETIAQKKESVFAKIFEEYYDRLPEEERFIIPNYSYLALTNYTVQKLPEKLVEILSFW

Nucleotide


Download         Length: 441 bp        

>NTDB_id=82491 R8625_RS10185 WP_001206586.1 1934729..1935169(-) (comR) [Streptococcus pneumoniae strain PZ900700054]
TTGCGAGAGTTTGGCGAAAAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAGTC
TGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAACACTAACAAAGTTAAAATATATCGCTG
AACGTTTGGGGGTTGAGGATTACAAGTTGATGCCAAGTTATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTC
TTGATGAGGACTCCTACATACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGCTAAGATTTTTGAAGAGTA
TTATGATAGGTTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTGGCACTAACGAACTACACAGTTCAAA
AATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(72-119)

Helix-turn-helix (HTH_3)

(8-59)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus pyogenes MGAS8232

54.167

82.192

0.445
  comR Streptococcus pyogenes MGAS315

52.5

82.192

0.432
  comR Streptococcus mutans UA159

52.5

82.192

0.432
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

53.636

75.342

0.404
  comR Streptococcus suis 05ZYH33

48.305

80.822

0.39
  comR Streptococcus suis P1/7

48.305

80.822

0.39
  comR Streptococcus suis D9

47.458

80.822

0.384
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

46.491

78.082

0.363

Multiple sequence alignment