Detailed information
Bioinformatically predicted
Overview
| Name | pilU | Type | Machinery gene |
| Locus tag | P5S46_RS17890 | Genome accession | NZ_CP120942 |
| Coordinates | 3861881..3862990 (+) | Length | 369 a.a. |
| NCBI ID | WP_010673049.1 | Uniprot ID | A0AAJ6CRB8 |
| Organism | Aeromonas caviae strain AC1520 | ||
| Function | type IV pilus retraction (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 3836666..3897659 | 3861881..3862990 | within | 0 |
Gene organization within MGE regions
Location: 3836666..3897659
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P5S46_RS17750 (P5S46_17750) | artM | 3837751..3838413 (-) | 663 | WP_010673075.1 | arginine ABC transporter permease ArtM | - |
| P5S46_RS17755 (P5S46_17755) | artQ | 3838416..3839066 (-) | 651 | WP_042014905.1 | arginine ABC transporter permease ArtQ | - |
| P5S46_RS17760 (P5S46_17760) | - | 3839070..3839807 (-) | 738 | WP_010673073.1 | arginine ABC transporter substrate-binding protein | - |
| P5S46_RS17765 (P5S46_17765) | - | 3839832..3840572 (-) | 741 | WP_041214472.1 | ATP-binding cassette domain-containing protein | - |
| P5S46_RS17770 (P5S46_17770) | argR | 3840773..3841243 (+) | 471 | WP_005308670.1 | transcriptional regulator ArgR | - |
| P5S46_RS17775 (P5S46_17775) | - | 3841323..3842228 (-) | 906 | WP_042864452.1 | Dyp-type peroxidase | - |
| P5S46_RS17780 (P5S46_17780) | - | 3842318..3843352 (-) | 1035 | WP_277856308.1 | ABC transporter ATP-binding protein | - |
| P5S46_RS17785 (P5S46_17785) | - | 3843393..3845018 (-) | 1626 | WP_277856309.1 | iron ABC transporter permease | - |
| P5S46_RS17790 (P5S46_17790) | - | 3845058..3846065 (-) | 1008 | WP_039039971.1 | Fe(3+) ABC transporter substrate-binding protein | - |
| P5S46_RS17795 (P5S46_17795) | glnK | 3846294..3846632 (-) | 339 | WP_005332325.1 | P-II family nitrogen regulator | - |
| P5S46_RS17800 (P5S46_17800) | arfB | 3846834..3847250 (+) | 417 | WP_010673067.1 | alternative ribosome rescue aminoacyl-tRNA hydrolase ArfB | - |
| P5S46_RS17805 (P5S46_17805) | - | 3847277..3847771 (+) | 495 | WP_277856310.1 | methylated-DNA--[protein]-cysteine S-methyltransferase | - |
| P5S46_RS17810 (P5S46_17810) | - | 3848373..3849569 (-) | 1197 | WP_041214468.1 | NupC/NupG family nucleoside CNT transporter | - |
| P5S46_RS17815 (P5S46_17815) | - | 3849753..3850688 (-) | 936 | WP_010673064.1 | LysR family transcriptional regulator | - |
| P5S46_RS17820 (P5S46_17820) | - | 3850771..3851307 (-) | 537 | WP_202044589.1 | glutathione peroxidase | - |
| P5S46_RS17825 (P5S46_17825) | - | 3851367..3851930 (-) | 564 | WP_042014912.1 | NnrU family protein | - |
| P5S46_RS17830 (P5S46_17830) | - | 3852193..3853326 (-) | 1134 | WP_277856311.1 | glycerate kinase | - |
| P5S46_RS17835 (P5S46_17835) | - | 3853336..3854598 (-) | 1263 | WP_236276030.1 | SLC13 family permease | - |
| P5S46_RS17840 (P5S46_17840) | - | 3854719..3855834 (-) | 1116 | WP_277856312.1 | sugar diacid recognition domain-containing protein | - |
| P5S46_RS17845 (P5S46_17845) | - | 3856041..3856415 (+) | 375 | WP_039039964.1 | YacL family protein | - |
| P5S46_RS17850 (P5S46_17850) | - | 3856465..3856755 (+) | 291 | WP_039039963.1 | hypothetical protein | - |
| P5S46_RS17855 (P5S46_17855) | - | 3856917..3857747 (+) | 831 | WP_041214463.1 | CPBP family intramembrane glutamic endopeptidase | - |
| P5S46_RS17860 (P5S46_17860) | - | 3857823..3858242 (-) | 420 | WP_041210940.1 | DUF4426 domain-containing protein | - |
| P5S46_RS17865 (P5S46_17865) | yggU | 3858261..3858560 (-) | 300 | WP_277856313.1 | DUF167 family protein YggU | - |
| P5S46_RS17870 (P5S46_17870) | - | 3858560..3859111 (-) | 552 | WP_010673053.1 | YggT family protein | - |
| P5S46_RS17875 (P5S46_17875) | proC | 3859135..3859959 (-) | 825 | WP_010673052.1 | pyrroline-5-carboxylate reductase | - |
| P5S46_RS17880 (P5S46_17880) | - | 3860082..3860783 (-) | 702 | WP_042864460.1 | YggS family pyridoxal phosphate-dependent enzyme | - |
| P5S46_RS17885 (P5S46_17885) | pilT | 3860823..3861857 (+) | 1035 | WP_010673050.1 | type IVa pilus ATPase TapT | Machinery gene |
| P5S46_RS17890 (P5S46_17890) | pilU | 3861881..3862990 (+) | 1110 | WP_010673049.1 | PilT/PilU family type 4a pilus ATPase | Machinery gene |
| P5S46_RS17895 (P5S46_17895) | yaaA | 3863023..3863796 (+) | 774 | WP_103857984.1 | peroxide stress protein YaaA | - |
| P5S46_RS17900 (P5S46_17900) | srmB | 3863984..3865204 (-) | 1221 | WP_041210934.1 | ATP-dependent RNA helicase SrmB | - |
| P5S46_RS17905 (P5S46_17905) | - | 3865332..3866042 (+) | 711 | WP_183149273.1 | methyltransferase | - |
| P5S46_RS17910 (P5S46_17910) | brnQ | 3866233..3867540 (+) | 1308 | WP_041211055.1 | branched-chain amino acid transport system II carrier protein | - |
| P5S46_RS17915 (P5S46_17915) | - | 3867630..3867857 (-) | 228 | WP_039039956.1 | hypothetical protein | - |
| P5S46_RS17920 (P5S46_17920) | - | 3867863..3868324 (-) | 462 | WP_010673043.1 | chemotaxis protein CheX | - |
| P5S46_RS17925 (P5S46_17925) | zur | 3868314..3868772 (-) | 459 | WP_010673042.1 | zinc uptake transcriptional repressor Zur | - |
| P5S46_RS17930 (P5S46_17930) | - | 3869353..3869616 (-) | 264 | WP_277856314.1 | pyocin activator PrtN family protein | - |
| P5S46_RS17935 (P5S46_17935) | - | 3869667..3871349 (-) | 1683 | WP_277856315.1 | DUF927 domain-containing protein | - |
| P5S46_RS17940 (P5S46_17940) | - | 3871928..3872275 (-) | 348 | WP_277856316.1 | hypothetical protein | - |
| P5S46_RS17945 (P5S46_17945) | - | 3872365..3873515 (+) | 1151 | WP_111736006.1 | IS3 family transposase | - |
| P5S46_RS17950 (P5S46_17950) | - | 3874667..3875776 (-) | 1110 | WP_045523182.1 | caspase family protein | - |
| P5S46_RS17955 (P5S46_17955) | - | 3875792..3878275 (-) | 2484 | WP_277856317.1 | effector-associated domain EAD1-containing protein | - |
| P5S46_RS17960 (P5S46_17960) | - | 3878272..3879132 (-) | 861 | WP_045523178.1 | hypothetical protein | - |
| P5S46_RS17965 (P5S46_17965) | - | 3879129..3880172 (-) | 1044 | WP_338405877.1 | hypothetical protein | - |
| P5S46_RS17970 (P5S46_17970) | - | 3880091..3881410 (-) | 1320 | WP_277856318.1 | GTPase-associated system all-helical protein GASH | - |
| P5S46_RS17975 (P5S46_17975) | - | 3881666..3882766 (-) | 1101 | WP_045523172.1 | site-specific integrase | - |
| P5S46_RS17980 (P5S46_17980) | dusA | 3882855..3883907 (+) | 1053 | WP_277856319.1 | tRNA dihydrouridine(20/20a) synthase DusA | - |
| P5S46_RS17985 (P5S46_17985) | - | 3883910..3884059 (+) | 150 | WP_010673040.1 | hypothetical protein | - |
| P5S46_RS17990 (P5S46_17990) | - | 3884142..3884567 (-) | 426 | WP_277856320.1 | hypothetical protein | - |
| P5S46_RS17995 (P5S46_17995) | hupA | 3884681..3884953 (-) | 273 | WP_005305063.1 | nucleoid-associated protein HU-alpha | - |
| P5S46_RS18000 (P5S46_18000) | - | 3885292..3885774 (+) | 483 | WP_029313757.1 | Rsd/AlgQ family anti-sigma factor | - |
| P5S46_RS18005 (P5S46_18005) | - | 3885877..3886263 (+) | 387 | WP_029313755.1 | PilZ domain-containing protein | - |
| P5S46_RS18010 (P5S46_18010) | radA | 3886317..3887681 (-) | 1365 | WP_277856321.1 | DNA repair protein RadA | - |
| P5S46_RS18015 (P5S46_18015) | - | 3887782..3890157 (+) | 2376 | WP_277856322.1 | PilZ domain-containing protein | - |
| P5S46_RS18020 (P5S46_18020) | - | 3890215..3891120 (-) | 906 | WP_042864464.1 | alpha/beta fold hydrolase | - |
| P5S46_RS18025 (P5S46_18025) | serB | 3891149..3892153 (-) | 1005 | WP_277856323.1 | phosphoserine phosphatase SerB | - |
| P5S46_RS18030 (P5S46_18030) | - | 3892347..3892955 (+) | 609 | WP_182936302.1 | AhpA/YtjB family protein | - |
| P5S46_RS18035 (P5S46_18035) | - | 3893021..3895276 (+) | 2256 | WP_277856324.1 | PAS domain S-box protein | - |
| P5S46_RS18040 (P5S46_18040) | - | 3895394..3896179 (-) | 786 | WP_233466745.1 | RT0821/Lpp0805 family surface protein | - |
| P5S46_RS18045 (P5S46_18045) | deoD | 3896312..3897025 (-) | 714 | WP_039039949.1 | purine-nucleoside phosphorylase | - |
Sequence
Protein
Download Length: 369 a.a. Molecular weight: 41000.18 Da Isoelectric Point: 6.4409
>NTDB_id=809479 P5S46_RS17890 WP_010673049.1 3861881..3862990(+) (pilU) [Aeromonas caviae strain AC1520]
MNMDVLLAALVEQKGSDLFITVDAPPTLKVNGRLVSLRPAPLDKTTALALIRESLDETHFERFLHTREANYAIQRGSLGR
FRVSAFWQQDMPGMVLRRIETRIPTFDELVLPPILQEVAMAKRGLVLFVGATGAGKSTTQAAMIGFRNQHGDGHILTVED
PVEFVHQHDRCLVTQREVGIDTASFDVALKNSLRQAPDVILIGEIRSQETMEFAIQFAETGHLCLATLHANNANQALDRI
LHLVPQEKHRQFLFDLSFNLRAIVAQQLLPSAHGQRRVAAFEILLNTPLVTDIIRKGEMHRLKEVMTKSGELGMQTFDQA
LFTLFCAGQIGYSEALAHADSANDLRLLIKLSGREQLGAGTLDNVTLDE
MNMDVLLAALVEQKGSDLFITVDAPPTLKVNGRLVSLRPAPLDKTTALALIRESLDETHFERFLHTREANYAIQRGSLGR
FRVSAFWQQDMPGMVLRRIETRIPTFDELVLPPILQEVAMAKRGLVLFVGATGAGKSTTQAAMIGFRNQHGDGHILTVED
PVEFVHQHDRCLVTQREVGIDTASFDVALKNSLRQAPDVILIGEIRSQETMEFAIQFAETGHLCLATLHANNANQALDRI
LHLVPQEKHRQFLFDLSFNLRAIVAQQLLPSAHGQRRVAAFEILLNTPLVTDIIRKGEMHRLKEVMTKSGELGMQTFDQA
LFTLFCAGQIGYSEALAHADSANDLRLLIKLSGREQLGAGTLDNVTLDE
Nucleotide
Download Length: 1110 bp
>NTDB_id=809479 P5S46_RS17890 WP_010673049.1 3861881..3862990(+) (pilU) [Aeromonas caviae strain AC1520]
ATGAACATGGATGTTCTGCTCGCCGCACTGGTTGAACAAAAGGGCTCGGATCTCTTCATCACGGTCGATGCCCCCCCGAC
CCTCAAGGTCAACGGGCGTCTGGTGTCGCTCAGGCCGGCTCCCCTCGACAAGACGACGGCGCTGGCGTTGATCAGGGAGA
GCCTGGACGAGACCCACTTCGAGCGCTTCCTGCACACCCGCGAGGCCAACTACGCCATCCAGCGAGGCTCGCTGGGGCGC
TTTCGGGTCAGCGCCTTCTGGCAACAGGATATGCCGGGCATGGTGCTGCGCCGCATCGAGACCCGCATCCCCACCTTTGA
CGAGCTGGTGCTGCCTCCCATCCTGCAGGAGGTCGCCATGGCCAAACGCGGGCTGGTGCTTTTCGTCGGCGCCACTGGCG
CCGGCAAGTCCACCACCCAGGCGGCCATGATAGGCTTTCGCAACCAGCACGGTGACGGCCACATCCTGACGGTGGAGGAT
CCGGTGGAGTTCGTCCATCAGCACGATCGCTGTCTGGTGACCCAGCGGGAGGTGGGGATCGACACCGCATCCTTCGATGT
CGCCCTCAAAAACTCCCTGCGCCAGGCCCCGGATGTCATCCTCATCGGTGAAATCCGCTCCCAGGAGACCATGGAGTTCG
CCATCCAGTTCGCCGAGACGGGGCACCTCTGCCTCGCCACCTTGCACGCCAACAATGCCAACCAGGCGCTGGATCGCATC
CTGCATCTGGTCCCCCAGGAGAAGCACCGCCAGTTCCTGTTCGATCTCTCCTTCAACCTGCGCGCCATCGTCGCCCAGCA
GCTGCTCCCCTCCGCTCATGGGCAGCGCCGGGTCGCCGCCTTCGAGATCCTGCTCAACACCCCGCTCGTCACCGACATCA
TCCGCAAGGGAGAGATGCACAGACTCAAGGAGGTGATGACCAAATCCGGCGAGCTCGGCATGCAGACCTTCGATCAGGCG
CTGTTCACCCTGTTCTGCGCCGGCCAAATTGGCTACAGTGAGGCCCTTGCCCATGCCGACTCCGCCAACGACCTGCGACT
GCTCATCAAGCTGTCGGGTCGCGAGCAGCTGGGCGCAGGCACTCTCGACAACGTGACCCTGGATGAATGA
ATGAACATGGATGTTCTGCTCGCCGCACTGGTTGAACAAAAGGGCTCGGATCTCTTCATCACGGTCGATGCCCCCCCGAC
CCTCAAGGTCAACGGGCGTCTGGTGTCGCTCAGGCCGGCTCCCCTCGACAAGACGACGGCGCTGGCGTTGATCAGGGAGA
GCCTGGACGAGACCCACTTCGAGCGCTTCCTGCACACCCGCGAGGCCAACTACGCCATCCAGCGAGGCTCGCTGGGGCGC
TTTCGGGTCAGCGCCTTCTGGCAACAGGATATGCCGGGCATGGTGCTGCGCCGCATCGAGACCCGCATCCCCACCTTTGA
CGAGCTGGTGCTGCCTCCCATCCTGCAGGAGGTCGCCATGGCCAAACGCGGGCTGGTGCTTTTCGTCGGCGCCACTGGCG
CCGGCAAGTCCACCACCCAGGCGGCCATGATAGGCTTTCGCAACCAGCACGGTGACGGCCACATCCTGACGGTGGAGGAT
CCGGTGGAGTTCGTCCATCAGCACGATCGCTGTCTGGTGACCCAGCGGGAGGTGGGGATCGACACCGCATCCTTCGATGT
CGCCCTCAAAAACTCCCTGCGCCAGGCCCCGGATGTCATCCTCATCGGTGAAATCCGCTCCCAGGAGACCATGGAGTTCG
CCATCCAGTTCGCCGAGACGGGGCACCTCTGCCTCGCCACCTTGCACGCCAACAATGCCAACCAGGCGCTGGATCGCATC
CTGCATCTGGTCCCCCAGGAGAAGCACCGCCAGTTCCTGTTCGATCTCTCCTTCAACCTGCGCGCCATCGTCGCCCAGCA
GCTGCTCCCCTCCGCTCATGGGCAGCGCCGGGTCGCCGCCTTCGAGATCCTGCTCAACACCCCGCTCGTCACCGACATCA
TCCGCAAGGGAGAGATGCACAGACTCAAGGAGGTGATGACCAAATCCGGCGAGCTCGGCATGCAGACCTTCGATCAGGCG
CTGTTCACCCTGTTCTGCGCCGGCCAAATTGGCTACAGTGAGGCCCTTGCCCATGCCGACTCCGCCAACGACCTGCGACT
GCTCATCAAGCTGTCGGGTCGCGAGCAGCTGGGCGCAGGCACTCTCGACAACGTGACCCTGGATGAATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilU | Vibrio cholerae strain A1552 |
60.326 |
99.729 |
0.602 |
| pilU | Pseudomonas stutzeri DSM 10701 |
58.974 |
95.122 |
0.561 |
| pilU | Acinetobacter baylyi ADP1 |
57.79 |
95.664 |
0.553 |
| pilT | Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 |
42.56 |
91.057 |
0.388 |
| pilT | Legionella pneumophila strain Lp02 |
40.816 |
92.954 |
0.379 |
| pilT | Legionella pneumophila strain ERS1305867 |
40.816 |
92.954 |
0.379 |