Detailed information NTG0809439

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: LLUC7005_RS08690
• Genome accession: NZ_CP120933
• Coordinates: 1775396..1776043 (-)
• Length: 215 a.a.
• NCBI ID: WP_004255240.1
• Uniprot ID: A0A1V0NHR8
• Organism: Lactococcus lactis subsp. lactis strain UC7005
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1770396..1781043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC7005_RS08665 (LLUC7005_08635)	atpF	1770466..1770972 (-)	507	WP_004255258.1	F0F1 ATP synthase subunit B	-
LLUC7005_RS08670 (LLUC7005_08640)	atpB	1770987..1771700 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
LLUC7005_RS08675 (LLUC7005_08645)	-	1771745..1771960 (-)	216	WP_014570694.1	F0F1 ATP synthase subunit C	-
LLUC7005_RS08680 (LLUC7005_08650)	-	1772144..1772920 (-)	777	WP_004255244.1	alpha/beta hydrolase family protein	-
LLUC7005_RS08685 (LLUC7005_08655)	comEC	1773205..1775415 (-)	2211	WP_014570695.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LLUC7005_RS08690 (LLUC7005_08660)	comEA	1775396..1776043 (-)	648	WP_004255240.1	ComEA family DNA-binding protein	Machinery gene
LLUC7005_RS08695 (LLUC7005_08665)	-	1776103..1777464 (-)	1362	WP_004255239.1	ABC transporter permease	-
LLUC7005_RS08700 (LLUC7005_08670)	-	1777461..1778393 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
LLUC7005_RS08705 (LLUC7005_08675)	-	1778498..1778896 (-)	399	WP_004255236.1	hypothetical protein	-
LLUC7005_RS08710 (LLUC7005_08680)	-	1779000..1779563 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-
LLUC7005_RS08715 (LLUC7005_08685)	-	1779736..1780914 (-)	1179	WP_014570696.1	SLC13 family permease	-

Sequence

Protein

• Length: 215 a.a.
• Molecular weight: 23651.83 Da
• Isoelectric Point: 5.0062

>NTDB_id=809439 LLUC7005_RS08690 WP_004255240.1 1775396..1776043(-) (comEA) [Lactococcus lactis subsp. lactis strain UC7005]
MDKILEKVKEYWKMIVLVVCGLIAGGIFYVLTNGQKPTTNLSVENLSSVSRQSSVSKFSEPNEKSVSKIMVDLKGAVTKP
NVYQISSDERLVDLIKEAGGFTDQADQKSINLSAKLKDEEVIYVPKIGENSSTENTDSSANSVTSQVSKTTEKININQAD
LTELQKLTGVGQKKAQDIIDFRTKNGDFKSLEDLGKVSGFGDKTLEKLKDELCFE

Nucleotide

• Length: 648 bp

>NTDB_id=809439 LLUC7005_RS08690 WP_004255240.1 1775396..1776043(-) (comEA) [Lactococcus lactis subsp. lactis strain UC7005]
ATGGATAAGATTTTAGAAAAAGTAAAAGAATATTGGAAAATGATTGTTTTAGTTGTTTGTGGGCTCATTGCTGGTGGGAT
TTTTTACGTTTTAACCAACGGTCAAAAGCCAACTACAAATCTGTCAGTAGAAAATTTAAGTTCTGTCAGCAGGCAAAGCT
CTGTCAGTAAATTTAGTGAACCTAATGAAAAATCTGTCAGTAAAATTATGGTTGATTTAAAAGGTGCGGTAACAAAGCCT
AATGTCTATCAAATTTCGTCAGATGAACGTCTAGTTGATTTAATTAAAGAAGCTGGTGGTTTTACTGACCAAGCTGACCA
GAAATCAATTAATCTGTCAGCAAAATTAAAAGATGAAGAAGTAATTTATGTCCCAAAAATTGGTGAAAATTCAAGCACAG
AAAATACTGACAGCTCTGCTAATTCGGTCACTAGTCAAGTCTCAAAAACCACTGAAAAAATAAATATCAATCAAGCAGAT
TTGACTGAACTACAAAAATTAACAGGTGTTGGTCAGAAAAAAGCTCAAGACATCATCGATTTTCGGACGAAAAATGGTGA
TTTCAAATCACTTGAAGACTTGGGAAAAGTTTCTGGTTTTGGAGATAAAACACTAGAAAAATTGAAAGATGAGTTGTGTT
TTGAATAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (70-125)

• Helix-hairpin-helix motif (HHH_3) (151-212)

3D structure

• AlphaFold DB: A0A1V0NHR8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Lactococcus lactis subsp. cremoris KW2	75.688	100	0.767
comEA/celA/cilE	Streptococcus mitis SK321	44.907	100	0.451
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	43.578	100	0.442
comEA/celA/cilE	Streptococcus pneumoniae Rx1	41.553	100	0.423
comEA/celA/cilE	Streptococcus pneumoniae D39	41.553	100	0.423
comEA/celA/cilE	Streptococcus pneumoniae R6	41.553	100	0.423
comEA/celA/cilE	Streptococcus mitis NCTC 12261	41.743	100	0.423
comEA	Latilactobacillus sakei subsp. sakei 23K	36.564	100	0.386
comEA	Staphylococcus aureus MW2	37.089	99.07	0.367