Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   P3X63_RS19280 Genome accession   NZ_CP120679
Coordinates   3714430..3715026 (+) Length   198 a.a.
NCBI ID   WP_026588863.1    Uniprot ID   A0A6I7F882
Organism   Bacillus sp. HSf4     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 3705851..3715026 3714430..3715026 within 0


Gene organization within MGE regions


Location: 3705851..3715026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3X63_RS19210 (P3X63_19210) - 3705851..3706303 (+) 453 WP_277691689.1 SHOCT domain-containing protein -
  P3X63_RS19215 (P3X63_19215) - 3706528..3707052 (-) 525 WP_277691690.1 GNAT family N-acetyltransferase -
  P3X63_RS19220 (P3X63_19220) - 3707060..3707254 (-) 195 WP_277691691.1 hypothetical protein -
  P3X63_RS19225 (P3X63_19225) - 3707515..3707835 (-) 321 Protein_3737 phage holin -
  P3X63_RS19230 (P3X63_19230) - 3707926..3708036 (-) 111 Protein_3738 peptidoglycan-binding protein -
  P3X63_RS19235 (P3X63_19235) - 3708064..3708178 (-) 115 Protein_3739 M15 family metallopeptidase -
  P3X63_RS19240 (P3X63_19240) - 3708286..3708426 (-) 141 WP_277691692.1 hypothetical protein -
  P3X63_RS19245 (P3X63_19245) - 3708423..3709523 (-) 1101 WP_277691693.1 aspartate phosphatase -
  P3X63_RS19250 (P3X63_19250) - 3709793..3711247 (+) 1455 WP_277691694.1 T7SS effector LXG polymorphic toxin -
  P3X63_RS19255 (P3X63_19255) - 3711261..3711566 (+) 306 WP_277691695.1 barstar family protein -
  P3X63_RS22765 - 3712271..3712765 (-) 495 WP_347176583.1 tyrosine-type recombinase/integrase -
  P3X63_RS19265 (P3X63_19265) - 3712918..3713496 (-) 579 Protein_3745 site-specific integrase -
  P3X63_RS19270 (P3X63_19270) - 3713509..3713850 (-) 342 WP_277691696.1 phage integrase N-terminal SAM-like domain-containing protein -
  P3X63_RS19280 (P3X63_19280) clpP 3714430..3715026 (+) 597 WP_026588863.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21805.96 Da        Isoelectric Point: 4.7982

>NTDB_id=807691 P3X63_RS19280 WP_026588863.1 3714430..3715026(+) (clpP) [Bacillus sp. HSf4]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPQVSTICTGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILSLRDKLNKILAERTGQ
PLEVIERDTDRDNFKTAEEAKEYGLIDKVLTRNVDSQK

Nucleotide


Download         Length: 597 bp        

>NTDB_id=807691 P3X63_RS19280 WP_026588863.1 3714430..3715026(+) (clpP) [Bacillus sp. HSf4]
ATGAATTTAATACCTACAGTCATTGAACAGACGAATCGCGGGGAAAGAGCGTATGACATTTACTCACGCCTGTTGAAAGA
CCGCATCATTATGCTGGGATCGGCAATCGATGACAATGTTGCGAACTCCATTGTATCACAGCTTTTATTCCTTGAAGCTG
AAGATCCTGAAAAAGATATCAGCATCTACATTAACAGCCCTGGCGGCTCAATCACAGCCGGTATGGCGATTTATGACACC
ATGCAGTTTATCAAGCCGCAGGTTTCTACGATTTGTACGGGAATGGCGGCATCCATGGGTGCGTTCCTTCTTGCTGCCGG
TGAGAAAGGGAAACGCTATGCCCTTCCAAATAGTGAAGTGATGATTCACCAGCCGCTTGGAGGCGCCCAAGGTCAGGCGA
CTGAAATTGAAATTGCCGCGAAGCGCATTCTTTCATTGCGCGACAAGCTGAACAAAATCCTTGCTGAGCGCACAGGACAG
CCGCTTGAAGTGATCGAGCGCGATACAGACCGCGACAACTTCAAAACGGCCGAAGAAGCAAAAGAATACGGCTTGATTGA
TAAAGTGCTGACACGCAATGTCGACTCGCAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I7F882

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

92.386

99.495

0.919
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.586

96.465

0.662
  clpP Streptococcus thermophilus LMG 18311

58.031

97.475

0.566
  clpP Streptococcus thermophilus LMD-9

58.031

97.475

0.566
  clpP Lactococcus lactis subsp. cremoris KW2

56.995

97.475

0.556
  clpP Streptococcus pneumoniae Rx1

56.995

97.475

0.556
  clpP Streptococcus pneumoniae D39

56.995

97.475

0.556
  clpP Streptococcus pneumoniae R6

56.995

97.475

0.556
  clpP Streptococcus pneumoniae TIGR4

56.995

97.475

0.556
  clpP Streptococcus pyogenes JRS4

55.44

97.475

0.54
  clpP Streptococcus pyogenes MGAS315

55.44

97.475

0.54
  clpP Streptococcus mutans UA159

54.639

97.98

0.535
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

54.922

97.475

0.535