Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   P3R60_RS09090 Genome accession   NZ_CP120510
Coordinates   1757279..1757986 (+) Length   235 a.a.
NCBI ID   WP_104968255.1    Uniprot ID   A0A2L0D523
Organism   Streptococcus pluranimalium strain SP21-2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1752279..1762986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3R60_RS09060 - 1752489..1753361 (+) 873 WP_316606259.1 sensor histidine kinase -
  P3R60_RS09065 - 1753358..1753957 (+) 600 WP_316606260.1 response regulator transcription factor -
  P3R60_RS09070 - 1754043..1754693 (-) 651 WP_104968259.1 amino acid ABC transporter permease -
  P3R60_RS09075 - 1754702..1755397 (-) 696 WP_316606261.1 amino acid ABC transporter permease -
  P3R60_RS09080 - 1755416..1756243 (-) 828 WP_316606262.1 transporter substrate-binding domain-containing protein -
  P3R60_RS09085 - 1756254..1757039 (-) 786 WP_278023883.1 amino acid ABC transporter ATP-binding protein -
  P3R60_RS09090 vicR 1757279..1757986 (+) 708 WP_104968255.1 response regulator YycF Regulator
  P3R60_RS09095 vicK 1757979..1759325 (+) 1347 WP_104968254.1 cell wall metabolism sensor histidine kinase VicK Regulator
  P3R60_RS09100 vicX 1759327..1760136 (+) 810 WP_316606263.1 MBL fold metallo-hydrolase Regulator
  P3R60_RS09105 rnc 1760371..1761072 (+) 702 WP_104968252.1 ribonuclease III -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26945.82 Da        Isoelectric Point: 4.7489

>NTDB_id=805877 P3R60_RS09090 WP_104968255.1 1757279..1757986(+) (vicR) [Streptococcus pluranimalium strain SP21-2]
MKTILVVDDERPISDIIKFNLSKEGYTIETAFDGHDAVEKFEDIKPDLVILDLMLPGMDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAQLRRVETIETVAEESLQSSPTEIEIGNLQILPEAFIAKKNGEEVEL
THREFELLYHLAQHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIETTPSRPEYILTRRGVGYFMKAHD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=805877 P3R60_RS09090 WP_104968255.1 1757279..1757986(+) (vicR) [Streptococcus pluranimalium strain SP21-2]
ATGAAAACAATTCTCGTTGTAGATGATGAAAGACCCATCTCAGACATTATAAAATTTAATCTGAGTAAGGAAGGCTATAC
TATTGAAACAGCCTTTGATGGTCATGACGCGGTTGAAAAATTTGAAGATATTAAGCCTGACTTGGTTATTTTGGACTTGA
TGCTGCCAGGTATGGATGGTCTTGAGGTAGCTAAAGAGATCCGTAAAACAAGTCACACGCCAATTATTATGTTATCGGCT
AAGGATTCTGAGTTCGATAAGGTGATTGGCTTGGAAATCGGTGCAGATGATTATGTCACAAAACCCTTTTCTAATCGAGA
GTTGTTGGCGCGTGTGAAAGCTCAACTACGTCGTGTTGAGACCATTGAAACTGTGGCAGAAGAATCTCTTCAATCCTCTC
CGACAGAAATCGAGATTGGGAACCTTCAAATCTTACCAGAGGCGTTTATTGCTAAAAAGAACGGAGAGGAAGTCGAGCTG
ACGCATCGTGAGTTTGAATTGCTCTATCATTTGGCGCAACATATTGGTCAAGTGATGACACGCGAGCATCTCCTTGAAAC
GGTTTGGGGATATGACTATTTTGGTGATGTTCGGACAGTTGATGTGACTATTCGTCGCCTCCGTGAAAAAATCGAGACAA
CTCCAAGTCGTCCGGAATACATTCTCACTCGTCGTGGAGTGGGATACTTTATGAAAGCTCATGACTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D523

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

79.574

100

0.796
  micA Streptococcus pneumoniae Cp1015

73.932

99.574

0.736
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  covR Streptococcus salivarius strain HSISS4

41.126

98.298

0.404
  scnR Streptococcus mutans UA159

36.864

100

0.37