Detailed information NTG0805878

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: P3R60_RS09095
• Genome accession: NZ_CP120510
• Coordinates: 1757979..1759325 (+)
• Length: 448 a.a.
• NCBI ID: WP_104968254.1
• Uniprot ID: A0A2L0D530
• Organism: Streptococcus pluranimalium strain SP21-2
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1752979..1764325

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P3R60_RS09065	-	1753358..1753957 (+)	600	WP_316606260.1	response regulator transcription factor	-
P3R60_RS09070	-	1754043..1754693 (-)	651	WP_104968259.1	amino acid ABC transporter permease	-
P3R60_RS09075	-	1754702..1755397 (-)	696	WP_316606261.1	amino acid ABC transporter permease	-
P3R60_RS09080	-	1755416..1756243 (-)	828	WP_316606262.1	transporter substrate-binding domain-containing protein	-
P3R60_RS09085	-	1756254..1757039 (-)	786	WP_278023883.1	amino acid ABC transporter ATP-binding protein	-
P3R60_RS09090	vicR	1757279..1757986 (+)	708	WP_104968255.1	response regulator YycF	Regulator
P3R60_RS09095	vicK	1757979..1759325 (+)	1347	WP_104968254.1	cell wall metabolism sensor histidine kinase VicK	Regulator
P3R60_RS09100	vicX	1759327..1760136 (+)	810	WP_316606263.1	MBL fold metallo-hydrolase	Regulator
P3R60_RS09105	rnc	1760371..1761072 (+)	702	WP_104968252.1	ribonuclease III	-

Sequence

Protein

• Length: 448 a.a.
• Molecular weight: 51137.14 Da
• Isoelectric Point: 4.7338

>NTDB_id=805878 P3R60_RS09095 WP_104968254.1 1757979..1759325(+) (vicK) [Streptococcus pluranimalium strain SP21-2]
MTDQFLFSFRDVIIAGLMSILVLIYVFLIIRDTLNSRRVQQLTEQVQALISGEYVVNQVTRGSAEVKDLAEHLNDLSEVF
RLTHENLGQEKNRLSSILSYMSDGVLATDRRGNIIMINDMARQQLNLSEEGDLAINIMTLLEDTSYTYHDLITKTPEVTL
HRVDEFGEFTVLRVNFALIKRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALKEAV
APGFIRVSLDETNRMMRMITDLLSLSRIDNNNSELEVELTNFTAFITYILNRFDRIKLQETHAGKSYDIKRNYDLTPVWI
EIDNDKMTQVFDNILNNAIKYSPDGGEIKVSMRTTDTQLIVSVSDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGLGL
AITKEIVKQHNGFIWAKSDYGKGSTFTIVLPYEKNILEVDEEWEVTED

Nucleotide

• Length: 1347 bp

>NTDB_id=805878 P3R60_RS09095 WP_104968254.1 1757979..1759325(+) (vicK) [Streptococcus pluranimalium strain SP21-2]
ATGACTGATCAATTTCTTTTTTCATTTCGAGATGTTATTATTGCAGGGCTAATGTCAATTTTAGTCCTGATTTATGTTTT
TTTAATTATTCGGGATACTTTAAATAGTCGACGTGTGCAACAATTGACGGAGCAAGTTCAAGCCTTGATTTCAGGTGAGT
ATGTGGTCAATCAGGTAACACGAGGAAGTGCTGAAGTTAAGGACTTAGCTGAACATTTGAACGATCTATCTGAGGTTTTT
CGTCTAACACATGAAAATTTAGGACAAGAAAAAAATCGTCTTTCAAGTATTTTATCCTATATGAGCGATGGGGTTTTAGC
AACAGACCGTCGTGGTAATATCATTATGATTAATGATATGGCAAGGCAACAGTTGAACTTATCAGAAGAAGGTGACCTTG
CCATCAATATTATGACTTTGCTAGAAGATACCTCGTATACTTATCATGATTTAATAACCAAAACACCCGAAGTAACGCTT
CACCGTGTCGATGAGTTTGGTGAATTTACGGTACTGAGGGTCAATTTTGCTCTTATCAAGAGAGAGAGTGGTTTTATATC
TGGTTTGGTAGCCGTTTTACACGATACAACAGAACAAGAAAAAGAGGAACGTGAACGTCGTCTCTTTGTTTCCAATGTTA
GTCATGAATTACGGACTCCTCTAACATCGGTAAAGTCGTATCTTGAAGCCTTGGATGAAGGGGCCCTTAAGGAAGCTGTT
GCCCCTGGGTTTATCCGTGTTTCCTTAGATGAAACAAACCGGATGATGCGGATGATTACAGACTTGCTATCCCTATCACG
TATTGATAATAATAATAGTGAATTAGAAGTTGAACTGACGAACTTTACAGCTTTTATCACCTATATCCTAAATCGTTTTG
ACCGCATCAAGTTACAGGAAACACATGCAGGAAAATCTTATGATATTAAGCGCAACTACGATCTGACTCCTGTTTGGATT
GAGATTGATAATGATAAGATGACCCAAGTTTTCGATAATATTTTAAACAATGCTATCAAGTATTCACCAGATGGTGGTGA
GATTAAGGTGAGCATGCGAACGACTGATACTCAATTAATTGTATCGGTATCTGATCAAGGATTGGGAATTCCTAAAAAAG
ACTTGCCTTTAATTTTTGACCGTTTCTACCGTGTTGATAAGGCAAGAAGCCGTGCCCAAGGAGGCACTGGACTTGGTCTA
GCAATTACCAAAGAAATTGTTAAACAACACAATGGCTTTATTTGGGCTAAAAGTGATTACGGTAAGGGATCAACGTTTAC
CATCGTTTTACCGTATGAAAAGAATATTTTAGAAGTAGACGAAGAATGGGAGGTAACTGAAGACTAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (206-270)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (323-433)

3D structure

• AlphaFold DB: A0A2L0D530

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	71.29	91.741	0.654
micB	Streptococcus pneumoniae Cp1015	64.896	96.652	0.627