Detailed information    

insolico Bioinformatically predicted

Overview


Name   clpP   Type   Regulator
Locus tag   PY824_RS08870 Genome accession   NZ_CP119172
Coordinates   1693685..1694275 (-) Length   196 a.a.
NCBI ID   WP_014295097.1    Uniprot ID   A0A081JFZ1
Organism   Streptococcus macedonicus strain SGM CIP105683     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context


Location: 1688685..1699275
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY824_RS08840 (PY824_08840) - 1688951..1689715 (-) 765 WP_115265900.1 ABC transporter ATP-binding protein -
  PY824_RS08845 (PY824_08845) - 1689715..1690668 (-) 954 WP_014295093.1 branched-chain amino acid ABC transporter permease -
  PY824_RS08850 (PY824_08850) - 1690672..1691556 (-) 885 WP_014295094.1 branched-chain amino acid ABC transporter permease -
  PY824_RS08855 (PY824_08855) - 1691608..1692789 (-) 1182 WP_115265901.1 ABC transporter substrate-binding protein -
  PY824_RS08860 (PY824_08860) - 1692902..1693153 (-) 252 WP_009854761.1 YlbG family protein -
  PY824_RS08865 (PY824_08865) - 1693250..1693588 (-) 339 Protein_1686 YlbF family regulator -
  PY824_RS08870 (PY824_08870) clpP 1693685..1694275 (-) 591 WP_014295097.1 ATP-dependent Clp protease proteolytic subunit Regulator
  PY824_RS08875 (PY824_08875) - 1694407..1695300 (-) 894 WP_014295098.1 DMT family transporter -
  PY824_RS08880 (PY824_08880) - 1695413..1696282 (+) 870 WP_014295099.1 LysR family transcriptional regulator -
  PY824_RS08885 (PY824_08885) upp 1696348..1696977 (-) 630 WP_014295100.1 uracil phosphoribosyltransferase -
  PY824_RS08890 (PY824_08890) - 1697136..1698299 (-) 1164 WP_014295101.1 MalY/PatB family protein -

Sequence


Protein


Download         Length: 196 a.a.        Molecular weight: 21548.54 Da        Isoelectric Point: 4.4901

>NTDB_id=798065 PY824_RS08870 WP_014295097.1 1693685..1694275(-) (clpP) [Streptococcus macedonicus strain SGM CIP105683]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKIRHNLEQILANNSGQ
TFEKVHADAERDNWMSAQETLEYGFIDEIMVNNELN

Nucleotide


Download         Length: 591 bp        

>NTDB_id=798065 PY824_RS08870 WP_014295097.1 1693685..1694275(-) (clpP) [Streptococcus macedonicus strain SGM CIP105683]
ATGATTCCCGTAGTTATTGAACAAACGAGCCGTGGTGAACGCTCATATGATATTTATTCACGCCTTTTGAAAGACCGTAT
TATCATGTTGACTGGACCAGTTGAAGATAATATGGCTAACTCTATCATTGCCCAATTGTTGTTCCTTGATGCACAAGATA
ACACTAAAGATATTTACCTTTATGTTAATACTCCTGGTGGTTCAGTATCAGCAGGACTTGCCATTGTTGATACAATGAAT
TTCATTAAATCAGATGTTCAAACAATTGTTATGGGTATGGCAGCTTCAATGGGAACTGTTATTGCGTCATCAGGTGCAAA
AGGTAAACGTTTCATGTTGCCAAATGCTGAATACATGATTCACCAACCAATGGGTGGTACTGGTGGCGGTACACAACAAA
CAGATATGGCAATTGCTGCCGAACACCTTTTGAAAATACGTCACAACTTGGAACAAATTTTGGCTAACAACTCTGGTCAA
ACATTTGAAAAAGTTCACGCTGACGCCGAACGTGATAACTGGATGAGTGCACAAGAAACCCTCGAATACGGCTTCATCGA
CGAAATCATGGTAAACAACGAATTAAACTAA

Domains


Predicted by InterproScan.

(11-192)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A081JFZ1

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

93.878

100

0.939

  clpP Streptococcus pneumoniae D39

93.878

100

0.939

  clpP Streptococcus pneumoniae R6

93.878

100

0.939

  clpP Streptococcus pneumoniae TIGR4

93.878

100

0.939

  clpP Streptococcus thermophilus LMG 18311

94.359

99.49

0.939

  clpP Streptococcus thermophilus LMD-9

94.359

99.49

0.939

  clpP Streptococcus pyogenes JRS4

90.306

100

0.903

  clpP Streptococcus pyogenes MGAS315

90.306

100

0.903

  clpP Streptococcus mutans UA159

87.245

100

0.872

  clpP Lactococcus lactis subsp. lactis strain DGCC12653

85.204

100

0.852

  clpP Lactococcus lactis subsp. cremoris KW2

84.694

100

0.847

  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

59.474

96.939

0.577

  clpP Bacillus subtilis subsp. subtilis str. 168

58.247

98.98

0.577