Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   PYW37_RS11990 Genome accession   NZ_CP118969
Coordinates   2341253..2342272 (-) Length   339 a.a.
NCBI ID   WP_044009599.1    Uniprot ID   A0AAW7ISZ3
Organism   Lactococcus lactis strain DSM 20481     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2336253..2347272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYW37_RS11945 - 2336383..2337192 (-) 810 WP_014570791.1 metal ABC transporter permease -
  PYW37_RS11950 - 2337185..2337922 (-) 738 WP_012898617.1 metal ABC transporter ATP-binding protein -
  PYW37_RS11955 - 2338099..2338941 (-) 843 WP_015427160.1 metal ABC transporter substrate-binding protein -
  PYW37_RS11960 - 2338938..2339375 (-) 438 WP_003129992.1 zinc-dependent MarR family transcriptional regulator -
  PYW37_RS11965 comGG 2339465..2339749 (-) 285 WP_025017139.1 competence type IV pilus minor pilin ComGG Machinery gene
  PYW37_RS11970 comGF 2339788..2340234 (-) 447 WP_032943612.1 competence type IV pilus minor pilin ComGF Machinery gene
  PYW37_RS11975 comGE 2340197..2340493 (-) 297 WP_010906316.1 competence type IV pilus minor pilin ComGE Machinery gene
  PYW37_RS11980 comGD 2340465..2340881 (-) 417 WP_025017137.1 competence type IV pilus minor pilin ComGD Machinery gene
  PYW37_RS11985 comGC 2340856..2341179 (-) 324 WP_032943614.1 competence type IV pilus major pilin ComGC Machinery gene
  PYW37_RS11990 comGB 2341253..2342272 (-) 1020 WP_044009599.1 competence type IV pilus assembly protein ComGB Machinery gene
  PYW37_RS11995 comGA 2342220..2343158 (-) 939 WP_031561106.1 competence type IV pilus ATPase ComGA Machinery gene

Sequence

Protein


Download         Length: 339 a.a.        Molecular weight: 38300.95 Da        Isoelectric Point: 10.0623

>NTDB_id=796978 PYW37_RS11990 WP_044009599.1 2341253..2342272(-) (comGB) [Lactococcus lactis strain DSM 20481]
MDISHLLKPKGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLASGQALSELLESLSFSKNV
VTQLALVEVHGNLSGTMQLVELHLKKQLEVKNKLVEVATYPILLLIFLVGIMWGLKNYLLPQLNSGSNFATLLINHLPLV
FFSFGAFIFLLTALSVTLFKRKSAIMNFTFLVKLPLVHSFIRLYLTAYFAREWGNLIAQGVELRQIINLMKKQKSRIFSE
VGKNLDLELNAGRSFEQAVSKLALFLPELSLMIEYGAIKDKLGLELSLYADECWEHFFTKIDRLMQLIQPLVFIFVALMI
ILLYAAMLLPIYSNMGSGI

Nucleotide


Download         Length: 1020 bp        

>NTDB_id=796978 PYW37_RS11990 WP_044009599.1 2341253..2342272(-) (comGB) [Lactococcus lactis strain DSM 20481]
ATGGATATCTCACACCTACTGAAGCCAAAAGGGAAAAAATTAAGACTGATTAAACAAGCCAAACTTATCCAACTGATGGG
AAATCTTTTGAATAGTGGATTTAATTTAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTA
CATTAAAAATGAAAGAAGGTCTCGCTTCTGGTCAAGCTTTATCAGAGCTTTTAGAAAGTCTTTCATTTTCTAAAAATGTG
GTGACACAACTTGCTTTGGTAGAAGTGCATGGTAACTTGTCAGGGACGATGCAATTAGTTGAACTTCATCTAAAAAAACA
GCTTGAAGTTAAAAATAAATTAGTGGAAGTTGCTACTTATCCAATATTGTTATTAATTTTTCTGGTTGGAATTATGTGGG
GCTTAAAAAATTATTTACTACCACAACTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTA
TTTTTTTCGTTTGGAGCTTTTATATTTTTACTGACAGCTTTGTCAGTAACTCTTTTTAAACGAAAATCAGCAATAATGAA
TTTTACATTTCTTGTTAAATTACCTCTGGTTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGG
GAAATCTAATTGCTCAAGGTGTTGAATTACGTCAAATTATTAACTTGATGAAAAAACAAAAAAGTCGAATTTTTTCAGAA
GTTGGCAAGAATCTTGATTTAGAATTGAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAAACTTGCGCTTTTTTTACC
CGAGCTCTCATTAATGATTGAATATGGAGCTATTAAAGATAAATTAGGCTTAGAGCTTTCGCTTTATGCGGATGAATGTT
GGGAACATTTTTTTACAAAGATAGATCGTTTAATGCAATTAATCCAACCTCTTGTTTTTATTTTCGTAGCATTGATGATT
ATTTTGCTATATGCAGCCATGTTACTCCCCATCTATTCAAATATGGGTTCTGGAATATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-330)

Type II secretion system (T2SS), protein F (T2SSF)

(23-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Lactococcus lactis subsp. cremoris KW2

83.432

99.705

0.832
  comYB Streptococcus gordonii str. Challis substr. CH1

53.593

98.525

0.528
  comGB/cglB Streptococcus mitis SK321

51.045

98.82

0.504
  comYB Streptococcus mutans UA140

53.968

92.92

0.501
  comGB/cglB Streptococcus pneumoniae TIGR4

50.746

98.82

0.501
  comGB/cglB Streptococcus pneumoniae D39

50.746

98.82

0.501
  comGB/cglB Streptococcus pneumoniae R6

50.746

98.82

0.501
  comGB/cglB Streptococcus pneumoniae Rx1

50.746

98.82

0.501
  comYB Streptococcus mutans UA159

53.651

92.92

0.499
  comGB/cglB Streptococcus mitis NCTC 12261

50.149

98.82

0.496