Detailed information NTG0796979

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: PYW37_RS11995
• Genome accession: NZ_CP118969
• Coordinates: 2342220..2343158 (-)
• Length: 312 a.a.
• NCBI ID: WP_031561106.1
• Uniprot ID: A0AAP8DEI2
• Organism: Lactococcus lactis strain DSM 20481
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2337220..2348158

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYW37_RS11955	-	2338099..2338941 (-)	843	WP_015427160.1	metal ABC transporter substrate-binding protein	-
PYW37_RS11960	-	2338938..2339375 (-)	438	WP_003129992.1	zinc-dependent MarR family transcriptional regulator	-
PYW37_RS11965	comGG	2339465..2339749 (-)	285	WP_025017139.1	competence type IV pilus minor pilin ComGG	Machinery gene
PYW37_RS11970	comGF	2339788..2340234 (-)	447	WP_032943612.1	competence type IV pilus minor pilin ComGF	Machinery gene
PYW37_RS11975	comGE	2340197..2340493 (-)	297	WP_010906316.1	competence type IV pilus minor pilin ComGE	Machinery gene
PYW37_RS11980	comGD	2340465..2340881 (-)	417	WP_025017137.1	competence type IV pilus minor pilin ComGD	Machinery gene
PYW37_RS11985	comGC	2340856..2341179 (-)	324	WP_032943614.1	competence type IV pilus major pilin ComGC	Machinery gene
PYW37_RS11990	comGB	2341253..2342272 (-)	1020	WP_044009599.1	competence type IV pilus assembly protein ComGB	Machinery gene
PYW37_RS11995	comGA	2342220..2343158 (-)	939	WP_031561106.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 35707.88 Da
• Isoelectric Point: 5.9473

>NTDB_id=796979 PYW37_RS11995 WP_031561106.1 2342220..2343158(-) (comGA) [Lactococcus lactis strain DSM 20481]
MIPKMAKELIQRAIDRDASDIYLIASKEKYKLYFRQMTARDLVEEIGLEVGLALLTHFKFLAGMNTGERRRVQLGACWYE
IEESNAKRLRLSTVGDFEGNESLVIRLLHDQNKELDFWFDEELENYDCKRGLHLFAGPVGSGKTSLMFDLARRHFTDLQV
ITIEEPVELIDSDFIQLQVNEVIGNSYDELIKLSLRHRPDLLIVGEIRDKLTAQAVLRASLTGYTVFSTVHASSVRGVIQ
RLSELGLSHWEIKNALSSVVYQRLIAGKGVLDIAKNEFESWSSENWNKKIDQLLTNGYLTPTEAKREKIKTD

Nucleotide

• Length: 939 bp

>NTDB_id=796979 PYW37_RS11995 WP_031561106.1 2342220..2343158(-) (comGA) [Lactococcus lactis strain DSM 20481]
ATGATACCAAAAATGGCAAAAGAATTAATTCAAAGAGCAATTGATAGAGATGCATCAGATATTTATCTGATTGCTTCAAA
AGAAAAGTATAAACTTTATTTTCGACAAATGACAGCACGTGATCTGGTAGAAGAAATTGGGTTAGAAGTTGGCTTAGCAC
TACTTACTCACTTTAAGTTTCTAGCTGGGATGAATACAGGAGAACGCAGACGAGTTCAATTGGGAGCTTGTTGGTATGAA
ATAGAGGAAAGTAATGCAAAACGTTTGCGTCTTTCGACAGTGGGGGATTTCGAGGGTAATGAATCTTTAGTAATACGTCT
CTTGCATGATCAAAACAAAGAACTTGATTTTTGGTTTGATGAAGAGCTAGAGAATTATGATTGTAAAAGAGGATTGCATC
TCTTTGCCGGTCCAGTAGGCTCGGGAAAAACATCTTTAATGTTTGATTTAGCTCGTCGTCATTTTACAGATTTACAAGTT
ATCACTATTGAAGAACCCGTTGAGTTGATTGATTCCGATTTTATTCAGTTACAAGTCAACGAAGTCATTGGTAATAGTTA
TGATGAATTAATTAAATTATCACTGAGGCATCGCCCAGATTTGTTAATCGTTGGTGAAATTCGTGATAAATTGACCGCTC
AAGCAGTTTTACGGGCTAGTTTGACAGGTTATACAGTGTTTTCAACCGTTCATGCCTCTTCTGTTAGAGGTGTCATTCAG
AGATTATCAGAGCTGGGTTTAAGTCATTGGGAAATAAAAAATGCTTTATCAAGTGTTGTTTATCAGCGTTTAATAGCTGG
GAAAGGAGTATTAGACATTGCCAAAAACGAATTTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTAC
TTACAAATGGATATCTCACACCTACTGAAGCCAAAAGGGAAAAAATTAAGACTGATTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (9-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Lactococcus lactis subsp. cremoris KW2	76.923	100	0.769
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	54.984	99.679	0.548
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	53.376	99.679	0.532
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	52.412	99.679	0.522
comGA/cglA/cilD	Streptococcus pneumoniae D39	52.412	99.679	0.522
comGA/cglA/cilD	Streptococcus pneumoniae R6	52.412	99.679	0.522
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	52.412	99.679	0.522
comYA	Streptococcus mutans UA159	52.244	100	0.522
comYA	Streptococcus mutans UA140	52.244	100	0.522
comYA	Streptococcus gordonii str. Challis substr. CH1	51.923	100	0.519