Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   PYW37_RS04270 Genome accession   NZ_CP118969
Coordinates   826564..827256 (+) Length   230 a.a.
NCBI ID   WP_012898209.1    Uniprot ID   A0AAW7IPJ0
Organism   Lactococcus lactis strain DSM 20481     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 821564..832256
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PYW37_RS04240 - 822295..823206 (+) 912 WP_023188699.1 CHAP domain-containing protein -
  PYW37_RS04245 - 823432..823794 (+) 363 WP_023188700.1 TIGR02328 family protein -
  PYW37_RS04250 - 823876..824337 (+) 462 WP_058222340.1 hypothetical protein -
  PYW37_RS04255 - 824410..825299 (+) 890 Protein_825 IS982 family transposase -
  PYW37_RS04260 - 825502..825747 (+) 246 WP_003130760.1 type B 50S ribosomal protein L31 -
  PYW37_RS04265 - 825878..826408 (+) 531 WP_012898210.1 DUF177 domain-containing protein -
  PYW37_RS04270 covR 826564..827256 (+) 693 WP_012898209.1 response regulator transcription factor Regulator
  PYW37_RS04275 covS 827265..828740 (+) 1476 WP_010906048.1 HAMP domain-containing histidine kinase Regulator
  PYW37_RS04280 - 828923..830164 (+) 1242 WP_025016683.1 ammonium transporter -
  PYW37_RS04285 - 830296..830637 (+) 342 WP_010906046.1 P-II family nitrogen regulator -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26670.33 Da        Isoelectric Point: 5.1273

>NTDB_id=796954 PYW37_RS04270 WP_012898209.1 826564..827256(+) (covR) [Lactococcus lactis strain DSM 20481]
MTSKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEASSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRTVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=796954 PYW37_RS04270 WP_012898209.1 826564..827256(+) (covR) [Lactococcus lactis strain DSM 20481]
ATGACTTCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCGCGATTCGTCTCATTAGAATTAGAACATGAAGG
CTATGCGACTGAGATTAAAGATAATGGTCGTTCTGGTCTTGAAGAAGCAAGTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGACGGTTTTGAGGTAGCTCGTCGTTTACGAAAAGAAAAAGATACACCAATCATTATGATG
ACGGCACGTGATTCAACGATGGACCGTGTTGCTGGTCTTGATATTGGGGCTGATGATTATATCACTAAACCTTTTGCGAT
TGAGGAACTTTTGGCGCGTGTTCGTGCTTTCTTCCGTCGTGAAGAGCATGGTCATGCCGTTGAACGTGCTGAAAATACTT
CTTTCCGTGATCTTGTGATTGACAAAACGAATCGCACCGTTCATCGTGGTAAAAAAGTAATTGATTTAACACGTCGTGAG
TATGACCTCCTTTTGACATTGATGCAAAATGTTGGCGATGTTGTGACTCGTGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACAGAAACAAATGTTGTGGATGTTTATATTCGTTATCTTAGAAATAAAATTGATGTTGAAGGTCAAGATA
GCTATATTCAAACTGTTCGTGGCTTAGGTTATGTAATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)

Response regulator receiver domain (Response_reg)

(6-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

99.565

100

0.996
  covR Streptococcus salivarius strain HSISS4

68.421

99.13

0.678
  vicR Streptococcus mutans UA159

45.887

100

0.461
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.435
  ciaR Streptococcus mutans UA159

37.611

98.261

0.37
  ciaR Streptococcus pneumoniae Rx1

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae D39

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae R6

36.726

98.261

0.361
  ciaR Streptococcus pneumoniae TIGR4

36.726

98.261

0.361