Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   PW252_RS03975 Genome accession   NZ_CP118735
Coordinates   746027..746731 (+) Length   234 a.a.
NCBI ID   WP_105114647.1    Uniprot ID   A0AA96VV35
Organism   Streptococcus iners strain 29887     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 741027..751731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS03950 (PW252_03950) - 741865..742728 (+) 864 WP_248051382.1 hypothetical protein -
  PW252_RS03955 (PW252_03955) - 742835..743494 (-) 660 WP_105125585.1 amino acid ABC transporter permease -
  PW252_RS03960 (PW252_03960) - 743507..744205 (-) 699 WP_248051384.1 amino acid ABC transporter permease -
  PW252_RS03965 (PW252_03965) - 744220..745065 (-) 846 WP_248051386.1 transporter substrate-binding domain-containing protein -
  PW252_RS03970 (PW252_03970) - 745076..745837 (-) 762 WP_248051388.1 amino acid ABC transporter ATP-binding protein -
  PW252_RS03975 (PW252_03975) vicR 746027..746731 (+) 705 WP_105114647.1 response regulator YycF Regulator
  PW252_RS03980 (PW252_03980) micB 746724..748073 (+) 1350 WP_172049898.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PW252_RS03985 (PW252_03985) vicX 748080..748883 (+) 804 WP_248045053.1 MBL fold metallo-hydrolase Regulator
  PW252_RS03990 (PW252_03990) vga(F) 749402..750781 (+) 1380 WP_248051391.1 ABC-F type ribosomal protection protein Vga(F) -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26769.78 Da        Isoelectric Point: 4.9842

>NTDB_id=794733 PW252_RS03975 WP_105114647.1 746027..746731(+) (vicR) [Streptococcus iners strain 29887]
MRKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALAVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELSETQMSVENTGSPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=794733 PW252_RS03975 WP_105114647.1 746027..746731(+) (vicR) [Streptococcus iners strain 29887]
ATGAGAAAAATTTTGATTGTAGATGATGAGAAACCCATCTCAGACATTATTAAATTTAATATGACCCGTGAGGGCTATGA
AGTCGTGACGGCTTTTGATGGTCGGGAAGCCTTGGCGGTTTTTGAAGCTGAATTTCCAGATATTGTGATTTTGGATTTGA
TGCTACCAGAGTTGGATGGTTTAGAAGTTGCTCGGACCATCCGTAAGACCAGCAATGTTCCCATTATTATGCTGTCTGCC
AAGGATAGTGAGTTTGACAAGGTGATTGGACTTGAGATTGGGGCAGATGACTATGTGACCAAGCCTTTCTCTAATCGTGA
ATTGCAGGCGCGTGTCAAGGCTCTCTTGCGTAGAAGCGAATTGTCAGAAACACAGATGTCCGTTGAGAATACTGGTAGTC
CTGAATTGGTCATCGGGGACTTGGTCATTTTGCCAGATGCCTTTGTTGCTAAGAAGCATGGCAAAGAATTGGAATTAACC
CACCGTGAGTTTGAATTGTTGCATCATTTAGCTAAGCATTTGGGGCAAGTTATGACCCGGGAGCATTTGCTAGAAACGGT
TTGGGGCTATGACTATTTTGGAGATGTGCGTACGGTGGACGTGACTATTCGCCGCTTGCGTGAAAAGATTGAAGATACAC
CAAGCCGACCGGAATATATTTTGACCCGTCGTGGTGTAGGATACTTTATCAAGGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

80.851

100

0.812
  micA Streptococcus pneumoniae Cp1015

80.687

99.573

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

42.857

98.718

0.423
  scnR Streptococcus mutans UA159

36.709

100

0.372