Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   PW252_RS03980 Genome accession   NZ_CP118735
Coordinates   746724..748073 (+) Length   449 a.a.
NCBI ID   WP_172049898.1    Uniprot ID   A0AA96W1I1
Organism   Streptococcus iners strain 29887     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 741724..753073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS03950 (PW252_03950) - 741865..742728 (+) 864 WP_248051382.1 hypothetical protein -
  PW252_RS03955 (PW252_03955) - 742835..743494 (-) 660 WP_105125585.1 amino acid ABC transporter permease -
  PW252_RS03960 (PW252_03960) - 743507..744205 (-) 699 WP_248051384.1 amino acid ABC transporter permease -
  PW252_RS03965 (PW252_03965) - 744220..745065 (-) 846 WP_248051386.1 transporter substrate-binding domain-containing protein -
  PW252_RS03970 (PW252_03970) - 745076..745837 (-) 762 WP_248051388.1 amino acid ABC transporter ATP-binding protein -
  PW252_RS03975 (PW252_03975) vicR 746027..746731 (+) 705 WP_105114647.1 response regulator YycF Regulator
  PW252_RS03980 (PW252_03980) micB 746724..748073 (+) 1350 WP_172049898.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PW252_RS03985 (PW252_03985) vicX 748080..748883 (+) 804 WP_248045053.1 MBL fold metallo-hydrolase Regulator
  PW252_RS03990 (PW252_03990) vga(F) 749402..750781 (+) 1380 WP_248051391.1 ABC-F type ribosomal protection protein Vga(F) -
  PW252_RS03995 (PW252_03995) pbp2b 750895..752940 (+) 2046 WP_398582953.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50831.07 Da        Isoelectric Point: 4.6636

>NTDB_id=794734 PW252_RS03980 WP_172049898.1 746724..748073(+) (micB) [Streptococcus iners strain 29887]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENHRDNKQIKQLNQRVKALMDGDYSEVLDMRGSPEITDMANSLNDLSE
VIRLTHDSLEQEKTRLSSILSYMSDGVIATDRVGRIIMINDMAQKQLGLAGKKQETLQILDVLDIKDRYSLRDLLAQTPE
IVLDHANENQEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNAESDKVYTIVRDYQISPIW
VELDTDKMTQVLDNILNNAIKYSPDGGTITFGMKTTDSQLIVSISDEGLGIPKADLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDITMDEWDDSDGEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=794734 PW252_RS03980 WP_172049898.1 746724..748073(+) (micB) [Streptococcus iners strain 29887]
ATGATTAATCAATTACGTTATTTAATGACAACAGCAGAGTTTTGGTTTGTTGTTATTCTCATTGGTTTTTTGATTGCATT
GACGGTCTTGTTGATTGAAAACCATAGGGATAATAAGCAAATCAAACAGCTCAATCAGCGTGTGAAAGCCTTGATGGATG
GTGATTATTCAGAAGTCTTGGACATGAGGGGAAGTCCGGAAATTACGGACATGGCCAACTCGCTCAATGATCTGTCGGAA
GTCATCCGTCTAACTCATGATAGCTTAGAACAGGAGAAAACCCGTCTGAGTTCTATCCTTTCTTATATGAGTGATGGGGT
CATTGCGACGGACCGAGTTGGTCGGATTATCATGATCAATGATATGGCACAAAAGCAACTGGGGCTAGCTGGAAAGAAAC
AAGAAACCTTGCAGATTTTAGATGTGTTGGATATTAAGGACCGCTATAGTCTGCGTGATTTGTTGGCACAGACACCTGAG
ATTGTTTTGGACCATGCCAATGAGAACCAGGAGTTTTTAACACTTCGAGCCAATTTTGCGACTATCCGGAGTGAGAGTGG
CTTGATTTCTGGTCTTGTTGTTGTCTTGCATGATATGACCGAGCAGGCTAAGGAGGAACGGGAACGCCGTCTATTTGTAT
CTAATGTCAGTCACGAACTCCGTACACCTTTGACATCCGTCAAATCCTATTTAGAAGCCCTAGATGAGGGAGCCTTGACG
GAATCAGTTGCACCTAGTTTTGTCAAGGTCTCCCTTGATGAAACCAATCGCATGATGCGGATGATCACGGACTTGCTCAG
TCTATCAAGGATTGATAACCAGGTTGGTCAAATAGATGTCGAACTAATCAACTTTACAGCCTTTGTGACCTTTATCCTTA
ACCGTTTTGACCAGATGAAAAATGCTGAGTCAGATAAGGTTTATACCATTGTGCGTGACTATCAAATCAGTCCTATTTGG
GTGGAGCTAGATACGGATAAGATGACCCAGGTGCTAGACAATATATTGAACAATGCTATCAAGTATTCGCCTGATGGTGG
TACTATTACCTTCGGTATGAAAACGACGGATAGTCAGTTGATTGTATCCATTTCTGATGAAGGGTTAGGCATTCCAAAGG
CTGACCTACCTAAGATCTTTGACCGATTTTATCGTGTGGATAAGGCTCGTTCGCGTGCCCAGGGTGGTACCGGTCTAGGT
TTGGCCATTGCCAAGGAAATCGTCAAGCAACACAAGGGCTTCATTTGGGCCAAGAGTGAATATGGACATGGCTCAACCTT
TACCATCGTCTTGCCATACAGTAAGGATATTACAATGGATGAATGGGATGATTCAGATGGAGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.642

97.105

0.686
  vicK Streptococcus mutans UA159

69.727

89.755

0.626