Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   PW220_RS03070 Genome accession   NZ_CP118734
Coordinates   580952..581656 (+) Length   234 a.a.
NCBI ID   WP_105114647.1    Uniprot ID   A0AA96VV35
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 575952..586656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS03045 (PW220_03045) - 576475..577338 (+) 864 WP_248054674.1 hypothetical protein -
  PW220_RS03050 (PW220_03050) - 577759..578418 (-) 660 WP_248054672.1 amino acid ABC transporter permease -
  PW220_RS03055 (PW220_03055) - 578431..579129 (-) 699 WP_172091624.1 amino acid ABC transporter permease -
  PW220_RS03060 (PW220_03060) - 579144..579989 (-) 846 WP_248054670.1 transporter substrate-binding domain-containing protein -
  PW220_RS03065 (PW220_03065) - 580000..580761 (-) 762 WP_105114648.1 amino acid ABC transporter ATP-binding protein -
  PW220_RS03070 (PW220_03070) vicR 580952..581656 (+) 705 WP_105114647.1 response regulator YycF Regulator
  PW220_RS03075 (PW220_03075) micB 581649..582998 (+) 1350 WP_172091625.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PW220_RS03080 (PW220_03080) vicX 583005..583808 (+) 804 WP_248054668.1 MBL fold metallo-hydrolase Regulator
  PW220_RS03085 (PW220_03085) vga(F) 584336..585715 (+) 1380 WP_248054667.1 ABC-F type ribosomal protection protein Vga(F) -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26769.78 Da        Isoelectric Point: 4.9842

>NTDB_id=794686 PW220_RS03070 WP_105114647.1 580952..581656(+) (vicR) [Streptococcus iners subsp. hyiners strain 29892]
MRKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALAVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELSETQMSVENTGSPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=794686 PW220_RS03070 WP_105114647.1 580952..581656(+) (vicR) [Streptococcus iners subsp. hyiners strain 29892]
ATGAGAAAAATTTTGATTGTAGATGATGAGAAACCCATCTCAGACATTATTAAATTTAATATGACCCGTGAGGGCTATGA
AGTCGTGACGGCTTTTGATGGTCGAGAGGCTTTGGCAGTTTTTGAAGCTGAATTTCCAGATATTGTGATTTTGGATTTGA
TGCTGCCAGAGTTGGATGGTTTAGAAGTTGCTCGGACCATCCGTAAGACCAGCAATGTTCCCATTATTATGCTGTCTGCC
AAGGATAGTGAGTTTGACAAGGTGATTGGACTTGAGATTGGGGCAGATGACTATGTGACCAAGCCTTTCTCTAATCGTGA
ATTGCAGGCGCGTGTCAAGGCTCTCTTGCGTAGAAGCGAATTGTCAGAAACACAGATGTCTGTTGAGAATACTGGCAGTC
CTGAATTGGTCATCGGGGACTTGGTCATTTTGCCAGATGCCTTTGTTGCTAAGAAGCATGGCAAAGAACTGGAATTGACC
CACCGTGAGTTTGAATTGTTGCATCATTTAGCTAAGCATTTGGGGCAAGTCATGACCCGGGAGCATTTGCTAGAAACAGT
ATGGGGCTATGACTATTTTGGAGATGTGCGTACGGTGGACGTAACTATTCGCCGTTTGCGTGAAAAAATTGAAGATACAC
CGAGCCGACCGGAATATATTTTGACCCGTCGTGGTGTAGGATACTTTATCAAGGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

80.851

100

0.812
  micA Streptococcus pneumoniae Cp1015

80.687

99.573

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

42.857

98.718

0.423
  scnR Streptococcus mutans UA159

36.709

100

0.372