Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   PW220_RS03075 Genome accession   NZ_CP118734
Coordinates   581649..582998 (+) Length   449 a.a.
NCBI ID   WP_172091625.1    Uniprot ID   -
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 576649..587998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS03050 (PW220_03050) - 577759..578418 (-) 660 WP_248054672.1 amino acid ABC transporter permease -
  PW220_RS03055 (PW220_03055) - 578431..579129 (-) 699 WP_172091624.1 amino acid ABC transporter permease -
  PW220_RS03060 (PW220_03060) - 579144..579989 (-) 846 WP_248054670.1 transporter substrate-binding domain-containing protein -
  PW220_RS03065 (PW220_03065) - 580000..580761 (-) 762 WP_105114648.1 amino acid ABC transporter ATP-binding protein -
  PW220_RS03070 (PW220_03070) vicR 580952..581656 (+) 705 WP_105114647.1 response regulator YycF Regulator
  PW220_RS03075 (PW220_03075) micB 581649..582998 (+) 1350 WP_172091625.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PW220_RS03080 (PW220_03080) vicX 583005..583808 (+) 804 WP_248054668.1 MBL fold metallo-hydrolase Regulator
  PW220_RS03085 (PW220_03085) vga(F) 584336..585715 (+) 1380 WP_248054667.1 ABC-F type ribosomal protection protein Vga(F) -
  PW220_RS03090 (PW220_03090) pbp2b 585829..587874 (+) 2046 WP_398582934.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50887.13 Da        Isoelectric Point: 4.6636

>NTDB_id=794687 PW220_RS03075 WP_172091625.1 581649..582998(+) (micB) [Streptococcus iners subsp. hyiners strain 29892]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENHRDNKQIKQLNQRVKALMDGDYTEVLDMRGSPEITDMANSLNDLSE
VIRLTHDSLEQEKTRLSSILSYMSDGVIATDRVGRIIMINDMAQKQLGLAGKKQEPLQILDVLDIKDRYSLRDLLAQTPE
IVLDHTNENQEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNAESDKVYSIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSISDEGLGIPKADLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDITMDEWDDSDGEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=794687 PW220_RS03075 WP_172091625.1 581649..582998(+) (micB) [Streptococcus iners subsp. hyiners strain 29892]
ATGATTAATCAATTACGTTATTTAATGACAACAGCAGAGTTTTGGTTTGTTGTTATTCTCATTGGTTTTTTGATTGCATT
GACGGTCTTGTTGATTGAAAACCATAGGGATAATAAGCAAATCAAACAGCTCAATCAGCGTGTGAAAGCCTTGATGGATG
GCGATTATACGGAGGTCTTGGATATGAGAGGCAGTCCAGAAATTACGGACATGGCCAACTCACTCAATGATCTGTCGGAA
GTCATCCGTCTAACTCATGATAGCTTAGAACAGGAGAAAACCCGTCTGAGTTCCATTCTTTCTTATATGAGTGATGGAGT
CATTGCGACGGACCGAGTTGGTCGGATTATCATGATCAATGATATGGCACAAAAGCAATTGGGGCTAGCCGGTAAGAAAC
AGGAGCCCTTGCAGATATTAGATGTTTTGGATATTAAGGATCGGTATAGTCTGCGTGATTTGTTGGCACAAACACCTGAG
ATTGTCTTAGACCATACCAATGAGAACCAAGAATTTCTGACCCTTCGGGCTAATTTTGCGACTATTCGGAGTGAGAGTGG
TTTGATTTCCGGTCTTGTTGTTGTCTTGCATGATATGACTGAACAGGCTAAAGAGGAACGGGAACGCCGTCTATTTGTAT
CCAATGTCAGTCACGAACTCCGTACACCTTTGACATCCGTCAAATCCTACCTAGAGGCCTTGGATGAGGGAGCCTTGACA
GAATCGGTCGCTCCAAGTTTTGTCAAGGTATCTCTGGATGAAACCAACCGTATGATGAGGATGATTACGGACTTGCTCAG
TCTATCAAGGATTGATAACCAGGTTGGTCAAATAGATGTCGAACTAATCAACTTTACAGCCTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAGATGAAAAATGCCGAGTCAGATAAGGTTTATTCCATTGTGCGTGACTATCAAATCAGTCCTATTTGG
GTGGAGATTGATACGGATAAGATGACCCAGGTGTTAGATAATATCTTAAACAATGCCATTAAGTATTCGCCTGATGGGGG
GACCATTACCTTTAGTATGAAAACGACGGATAGTCAGTTGATTGTATCCATTTCTGATGAAGGGTTAGGCATTCCAAAGG
CTGATCTACCTAAGATCTTTGACCGATTTTATCGTGTGGATAAGGCTCGTTCGCGTGCCCAGGGTGGTACTGGTCTAGGT
TTGGCCATTGCCAAAGAAATTGTCAAGCAACATAAGGGCTTCATTTGGGCCAAGAGTGAATATGGACATGGGTCAACGTT
TACGATAGTTCTGCCTTACAGTAAGGATATTACTATGGATGAGTGGGATGATTCAGATGGAGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.642

97.105

0.686
  vicK Streptococcus mutans UA159

70.223

89.755

0.63