Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   PXH68_RS06385 Genome accession   NZ_CP118733
Coordinates   1386776..1387480 (-) Length   234 a.a.
NCBI ID   WP_202848347.1    Uniprot ID   A0AA97A9E1
Organism   Streptococcus suivaginalis strain 29896     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1381776..1392480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PXH68_RS06365 (PXH68_06365) recR 1381807..1382403 (-) 597 WP_014637682.1 recombination mediator RecR -
  PXH68_RS06370 (PXH68_06370) pbp2b 1382412..1384484 (-) 2073 WP_248028751.1 penicillin-binding protein PBP2B -
  PXH68_RS06375 (PXH68_06375) vicX 1384624..1385427 (-) 804 WP_205031778.1 MBL fold metallo-hydrolase Regulator
  PXH68_RS06380 (PXH68_06380) micB 1385434..1386783 (-) 1350 WP_202848346.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PXH68_RS06385 (PXH68_06385) micA 1386776..1387480 (-) 705 WP_202848347.1 response regulator YycF Regulator
  PXH68_RS06390 (PXH68_06390) - 1387656..1388417 (+) 762 WP_202848348.1 amino acid ABC transporter ATP-binding protein -
  PXH68_RS06395 (PXH68_06395) - 1388428..1389267 (+) 840 WP_248028752.1 transporter substrate-binding domain-containing protein -
  PXH68_RS06400 (PXH68_06400) - 1389282..1389980 (+) 699 WP_248028753.1 amino acid ABC transporter permease -
  PXH68_RS06405 (PXH68_06405) - 1389995..1390654 (+) 660 WP_248028754.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26839.69 Da        Isoelectric Point: 4.8135

>NTDB_id=794640 PXH68_RS06385 WP_202848347.1 1386776..1387480(-) (micA) [Streptococcus suivaginalis strain 29896]
MKKILVVDDERPISDIIKFNMTREGYEVVTAFDGKEALERFEAEFPDIVILDLMLPEIDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELSETQVDSDNQGTPEIVIGDLVIVPDAFVAKKHGKELELT
HREFELLHHLANHLGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDLPSRPEYILTRRGVGYYIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=794640 PXH68_RS06385 WP_202848347.1 1386776..1387480(-) (micA) [Streptococcus suivaginalis strain 29896]
ATGAAAAAAATTCTAGTTGTTGATGATGAGAGACCAATCTCCGATATTATCAAGTTTAACATGACCAGAGAGGGCTATGA
AGTCGTGACAGCCTTCGATGGGAAAGAAGCCTTGGAACGATTTGAAGCAGAATTTCCAGATATTGTGATTTTGGATTTGA
TGCTGCCTGAAATAGATGGGCTAGAAGTGGCACGTACCATTCGTAAGACCAGTAATGTACCGATTTTGATGCTGTCGGCT
AAGGACAGTGAATTTGATAAGGTTATTGGATTGGAAATCGGGGCAGATGATTATGTAACCAAGCCATTTTCAAATCGTGA
ATTGCAGGCGCGTGTCAAGGCTCTTTTACGCCGTAGTGAATTGTCTGAAACCCAAGTCGATAGTGACAACCAGGGGACTC
CTGAAATTGTCATTGGTGATTTGGTCATCGTACCAGATGCCTTTGTGGCTAAAAAGCACGGGAAAGAGTTGGAATTGACC
CACCGTGAGTTTGAGTTGCTGCACCATCTGGCCAATCATTTGGGACAGGTGATGACACGGGAACACTTGCTTGAAACAGT
CTGGGGTTACGATTACTTTGGGGATGTCCGTACAGTAGATGTGACAGTCCGTCGTTTGCGTGAAAAAATTGAAGACTTGC
CAAGCCGTCCAGAATACATTTTGACTCGCCGTGGCGTAGGCTACTATATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.906

100

0.829
  vicR Streptococcus mutans UA159

79.574

100

0.799
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.174

98.291

0.415
  covR Streptococcus salivarius strain HSISS4

41.991

98.718

0.415
  scnR Streptococcus mutans UA159

37.553

100

0.38