Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   PXH68_RS06380 Genome accession   NZ_CP118733
Coordinates   1385434..1386783 (-) Length   449 a.a.
NCBI ID   WP_202848346.1    Uniprot ID   A0AA97A0A6
Organism   Streptococcus suivaginalis strain 29896     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1380434..1391783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PXH68_RS06360 (PXH68_06360) - 1380679..1381725 (-) 1047 WP_248028750.1 D-alanine--D-alanine ligase -
  PXH68_RS06365 (PXH68_06365) recR 1381807..1382403 (-) 597 WP_014637682.1 recombination mediator RecR -
  PXH68_RS06370 (PXH68_06370) pbp2b 1382412..1384484 (-) 2073 WP_248028751.1 penicillin-binding protein PBP2B -
  PXH68_RS06375 (PXH68_06375) vicX 1384624..1385427 (-) 804 WP_205031778.1 MBL fold metallo-hydrolase Regulator
  PXH68_RS06380 (PXH68_06380) micB 1385434..1386783 (-) 1350 WP_202848346.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PXH68_RS06385 (PXH68_06385) micA 1386776..1387480 (-) 705 WP_202848347.1 response regulator YycF Regulator
  PXH68_RS06390 (PXH68_06390) - 1387656..1388417 (+) 762 WP_202848348.1 amino acid ABC transporter ATP-binding protein -
  PXH68_RS06395 (PXH68_06395) - 1388428..1389267 (+) 840 WP_248028752.1 transporter substrate-binding domain-containing protein -
  PXH68_RS06400 (PXH68_06400) - 1389282..1389980 (+) 699 WP_248028753.1 amino acid ABC transporter permease -
  PXH68_RS06405 (PXH68_06405) - 1389995..1390654 (+) 660 WP_248028754.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50638.74 Da        Isoelectric Point: 4.5834

>NTDB_id=794639 PXH68_RS06380 WP_202848346.1 1385434..1386783(-) (micB) [Streptococcus suivaginalis strain 29896]
MINQLRYLITTAEFWFIVIIIGFVIALTVLLLENHKDNRQIKLLNAKVQSLISGDYSEVLDLRGSPEITDMTNSLNDLSE
VIRLTQDNLTQEKTRLSSILSYMSDGVMATDRMGRVIMINDMAQKQLGLSAKSGENASLIEILELGDKYSFRELLAQTPE
VVLEHANENGEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
EAVAPSFVKVSLEETNRMMRMISDLLSLSRIDNQVGTMDVELINFTAFVTFILNRFDQMKSQSTDKEYSIVRDYQITPIW
VEIDTDKMTQVIDNILNNAIKYSPDGGKITFSMKTTDSQLIVSISDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHQGFIWAKSEYGHGSTFTIVLPYSKDISFDDWDEATEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=794639 PXH68_RS06380 WP_202848346.1 1385434..1386783(-) (micB) [Streptococcus suivaginalis strain 29896]
ATGATTAATCAATTACGTTATCTGATCACAACGGCAGAATTTTGGTTTATTGTGATCATCATCGGCTTTGTCATCGCCTT
GACAGTGCTGCTTTTGGAAAACCACAAGGACAATCGGCAAATCAAACTCCTCAATGCTAAGGTCCAGTCTTTGATTTCTG
GTGACTACTCAGAGGTCTTGGATTTAAGAGGGAGCCCTGAAATTACTGATATGACCAATTCGTTGAATGATCTGTCAGAA
GTGATTCGCCTGACCCAGGACAATTTAACCCAAGAAAAAACACGTCTTTCTTCTATCTTATCCTATATGAGCGATGGTGT
GATGGCGACGGATCGAATGGGGCGGGTCATTATGATCAATGATATGGCTCAAAAGCAACTGGGACTGTCGGCAAAATCAG
GGGAAAATGCCAGTCTGATTGAGATTTTAGAATTAGGTGACAAGTATAGCTTCCGAGAACTCTTGGCCCAAACGCCTGAG
GTTGTTTTGGAGCATGCAAATGAAAATGGAGAATTTTTGACCCTTCGTGCTAATTTTGCGACTATTAGGAGTGAGAGTGG
CTTGATTTCTGGTTTGGTTGTGGTCTTACACGACATGACGGAGCAGGCCAAGGAAGAACGAGAACGACGCCTCTTTGTAT
CCAATGTCAGTCATGAACTGCGAACGCCTCTTACCTCGGTTAAGTCCTATCTGGAGGCGCTTGATGAGGGGGCTTTGACA
GAGGCGGTTGCCCCAAGTTTTGTCAAAGTGTCTTTGGAAGAAACCAACCGCATGATGCGAATGATTTCAGACCTCTTGAG
TTTATCGCGTATTGATAACCAAGTGGGGACCATGGATGTGGAGTTGATTAACTTTACGGCATTTGTGACCTTTATTCTCA
ACCGTTTTGATCAAATGAAAAGTCAATCAACCGATAAGGAATACAGCATTGTCCGTGATTATCAGATTACACCGATTTGG
GTTGAAATTGATACAGATAAGATGACCCAGGTAATCGACAATATCTTAAACAATGCCATCAAGTATTCGCCAGACGGGGG
CAAGATTACCTTCAGCATGAAGACAACCGACTCTCAGTTGATTGTGTCAATTTCAGATGAAGGTCTAGGCATTCCTAAGG
CAGACTTGCCTCGGATCTTTGACCGTTTTTATCGAGTTGACAAGGCTCGGTCTCGGGCGCAGGGGGGGACAGGTTTAGGA
TTGGCGATTGCTAAAGAAATTATCAAACAGCACCAGGGCTTTATCTGGGCCAAGAGTGAATATGGTCATGGTTCGACCTT
TACCATCGTCTTGCCTTATAGCAAGGATATCAGTTTTGATGACTGGGATGAAGCAACTGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.413

97.105

0.684
  vicK Streptococcus mutans UA159

69.231

89.755

0.621