Detailed information NTG0794628

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: PXH68_RS05060
• Genome accession: NZ_CP118733
• Coordinates: 1087556..1088230 (-)
• Length: 224 a.a.
• NCBI ID: WP_158455078.1
• Uniprot ID: -
• Organism: Streptococcus suivaginalis strain 29896
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1082556..1093230

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PXH68_RS05035 (PXH68_05035)	-	1082865..1084142 (-)	1278	WP_248028149.1	pyrimidine-nucleoside phosphorylase	-
PXH68_RS05040 (PXH68_05040)	-	1084139..1084729 (-)	591	WP_248028148.1	class I SAM-dependent methyltransferase	-
PXH68_RS05045 (PXH68_05045)	coaA	1084838..1085758 (+)	921	WP_158455069.1	type I pantothenate kinase	-
PXH68_RS05050 (PXH68_05050)	rpsT	1085817..1086065 (+)	249	WP_187321597.1	30S ribosomal protein S20	-
PXH68_RS05055 (PXH68_05055)	ciaH	1086169..1087566 (-)	1398	WP_248028147.1	sensor histidine kinase	Regulator
PXH68_RS05060 (PXH68_05060)	ciaR	1087556..1088230 (-)	675	WP_158455078.1	response regulator transcription factor	Regulator
PXH68_RS05065 (PXH68_05065)	-	1088352..1088705 (-)	354	WP_248028146.1	hypothetical protein	-
PXH68_RS05070 (PXH68_05070)	phoU	1088951..1089607 (-)	657	WP_158455084.1	phosphate signaling complex protein PhoU	-
PXH68_RS05075 (PXH68_05075)	pstB	1089652..1090410 (-)	759	WP_158455087.1	phosphate ABC transporter ATP-binding protein PstB	-
PXH68_RS05080 (PXH68_05080)	pstB	1090422..1091225 (-)	804	WP_158455090.1	phosphate ABC transporter ATP-binding protein PstB	-
PXH68_RS05085 (PXH68_05085)	pstA	1091251..1092135 (-)	885	WP_158455092.1	phosphate ABC transporter permease PstA	-
PXH68_RS05090 (PXH68_05090)	pstC	1092125..1093042 (-)	918	WP_172044202.1	phosphate ABC transporter permease subunit PstC	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25383.03 Da
• Isoelectric Point: 4.2651

>NTDB_id=794628 PXH68_RS05060 WP_158455078.1 1087556..1088230(-) (ciaR) [Streptococcus suivaginalis strain 29896]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGDEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENILTYGDMTVDLATNSTHVDGKEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGSAFGENLQTLRSVGYILKNVD

Nucleotide

• Length: 675 bp

>NTDB_id=794628 PXH68_RS05060 WP_158455078.1 1087556..1088230(-) (ciaR) [Streptococcus suivaginalis strain 29896]
ATGATAAAGATTTTGCTTGTAGAGGATGATCTTAGTTTATCCAATTCAGTATTTGATTTTTTAGATGATTTTGCAGATGT
GATGCAAGTTTTTGATGGTGATGAAGGCTTGTATGAAGCCGAATCAGGTGTTTACGATTTAATTCTCCTTGACTTGATGT
TACCAGAAAAAGATGGTTTCCAAGTCTTGAAAGAACTGCGTGAAAAAGGAGTGACGACTCCAGTACTGATTACGACTGCT
AAGGAAAGTTTGGATGATAAGGGACATGGTTTTGAATTGGGGGCAGATGATTATCTGACAAAACCATTCTACTTAGAAGA
GCTAAAAATGCGGATTCAAGCCTTGCTCAAACGCTCTGGAAAATTTAACGAAAACATTCTGACTTATGGAGATATGACAG
TGGATCTTGCGACCAATTCTACGCATGTAGATGGGAAAGAGGTTGAACTTCTAGGGAAGGAGTTTGATTTATTGGTCTAT
TTCTTGCAAAATCAAAACGTTATCTTACCAAAAACACAAATTTTTGACCGTATTTGGGGATTCGATAGTGACACTACCAT
CTCAGTTGTCGAAGTATATGTGTCGAAAATTCGTAAAAAATTGAAAGGTTCAGCATTTGGTGAGAATCTACAGACTCTCC
GAAGTGTTGGTTACATTTTGAAAAATGTTGACTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.179	100	0.902
ciaR	Streptococcus pneumoniae Rx1	88.789	99.554	0.884
ciaR	Streptococcus pneumoniae D39	88.789	99.554	0.884
ciaR	Streptococcus pneumoniae R6	88.789	99.554	0.884
ciaR	Streptococcus pneumoniae TIGR4	88.789	99.554	0.884
covR	Lactococcus lactis subsp. lactis strain DGCC12653	36.889	100	0.371
vicR	Streptococcus mutans UA159	34.746	100	0.366
covR	Streptococcus salivarius strain HSISS4	36.283	100	0.366