Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   PXH68_RS05055 Genome accession   NZ_CP118733
Coordinates   1086169..1087566 (-) Length   465 a.a.
NCBI ID   WP_248028147.1    Uniprot ID   A0AA96ZZH2
Organism   Streptococcus suivaginalis strain 29896     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1081169..1092566
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PXH68_RS05025 (PXH68_05025) - 1081811..1082200 (-) 390 WP_205030801.1 cytidine deaminase -
  PXH68_RS05030 (PXH68_05030) deoC 1082187..1082849 (-) 663 WP_248028150.1 deoxyribose-phosphate aldolase -
  PXH68_RS05035 (PXH68_05035) - 1082865..1084142 (-) 1278 WP_248028149.1 pyrimidine-nucleoside phosphorylase -
  PXH68_RS05040 (PXH68_05040) - 1084139..1084729 (-) 591 WP_248028148.1 class I SAM-dependent methyltransferase -
  PXH68_RS05045 (PXH68_05045) coaA 1084838..1085758 (+) 921 WP_158455069.1 type I pantothenate kinase -
  PXH68_RS05050 (PXH68_05050) rpsT 1085817..1086065 (+) 249 WP_187321597.1 30S ribosomal protein S20 -
  PXH68_RS05055 (PXH68_05055) ciaH 1086169..1087566 (-) 1398 WP_248028147.1 sensor histidine kinase Regulator
  PXH68_RS05060 (PXH68_05060) ciaR 1087556..1088230 (-) 675 WP_158455078.1 response regulator transcription factor Regulator
  PXH68_RS05065 (PXH68_05065) - 1088352..1088705 (-) 354 WP_248028146.1 hypothetical protein -
  PXH68_RS05070 (PXH68_05070) phoU 1088951..1089607 (-) 657 WP_158455084.1 phosphate signaling complex protein PhoU -
  PXH68_RS05075 (PXH68_05075) pstB 1089652..1090410 (-) 759 WP_158455087.1 phosphate ABC transporter ATP-binding protein PstB -
  PXH68_RS05080 (PXH68_05080) pstB 1090422..1091225 (-) 804 WP_158455090.1 phosphate ABC transporter ATP-binding protein PstB -
  PXH68_RS05085 (PXH68_05085) pstA 1091251..1092135 (-) 885 WP_158455092.1 phosphate ABC transporter permease PstA -

Sequence

Protein


Download         Length: 465 a.a.        Molecular weight: 52780.02 Da        Isoelectric Point: 4.8350

>NTDB_id=794627 PXH68_RS05055 WP_248028147.1 1086169..1087566(-) (ciaH) [Streptococcus suivaginalis strain 29896]
MLTKSKKLFSTDNFSYFIRYFAVFTLIFVSMTIMIFQVMRATMYRSSDENFQLIASDPGMIMGFAMARGLSPDVDVVFEQ
SNQESTNSSETESFETTSSSSKQNFMPPYQPQTKIRLNTNYHIILFDGEGNRLNAVDDVSGLADVSLNTKDLNQIEEIEV
TTAFEDVEYYRTMTIQLDSSAYAAYSDLGVEYATILFNTSQIKSSIASYETTVVVVMISFWLISIFASFYLANLSMRPIL
ISFQKQKDFVENASHELHTPLAVLQNRLESLFRHPEATILESSENIASSLEEVRNMRLLTTNLLNLARREDGLKPDLSEV
GPEFFEDVFENYGIIAEENGKELTVTNHVHQLVKTDKVLLKQLMTILFDNAMKYSDEDGKIELTVFIKDRNLHLLVSDNG
IGISAEDKKKIFDRFYRVDKARTRQKGGFGLGLSLAKQIVQSLNGDIQVKNNQPKGTVFEVKLPR

Nucleotide


Download         Length: 1398 bp        

>NTDB_id=794627 PXH68_RS05055 WP_248028147.1 1086169..1087566(-) (ciaH) [Streptococcus suivaginalis strain 29896]
ATGTTGACTAAATCAAAAAAACTTTTTTCAACGGATAATTTTTCGTATTTTATCCGTTATTTTGCTGTTTTTACATTGAT
TTTCGTCTCGATGACCATCATGATTTTCCAAGTCATGCGCGCGACCATGTATCGCTCGTCAGATGAAAATTTTCAACTAA
TTGCCAGTGACCCTGGCATGATTATGGGATTTGCCATGGCGAGAGGGCTTTCACCGGATGTCGATGTAGTCTTTGAGCAA
TCCAATCAAGAATCGACTAACTCATCAGAGACAGAGTCATTTGAAACGACTAGTTCTTCTTCAAAGCAGAATTTTATGCC
TCCCTATCAGCCACAGACAAAAATTCGTCTCAATACCAATTACCATATCATTCTTTTTGATGGAGAAGGTAATCGTTTGA
ATGCGGTTGATGATGTCTCAGGTCTTGCTGATGTTTCACTAAATACCAAGGATTTGAATCAAATCGAAGAAATAGAAGTG
ACTACGGCATTTGAGGATGTGGAGTACTATCGGACGATGACGATTCAATTGGACAGTTCAGCCTATGCGGCCTATTCCGA
TTTAGGAGTGGAGTATGCGACGATTTTATTCAATACGAGTCAAATCAAGTCTTCGATTGCATCCTATGAAACAACAGTAG
TGGTTGTGATGATCAGTTTCTGGTTGATTTCGATATTTGCTAGTTTTTATCTAGCCAATCTAAGCATGCGTCCTATTTTG
ATTAGCTTTCAAAAGCAGAAGGATTTTGTAGAAAATGCCAGCCATGAATTGCATACACCCTTGGCTGTTTTACAGAATCG
CTTGGAAAGCCTTTTCCGTCATCCAGAGGCAACCATTCTAGAGAGTAGTGAAAATATTGCCTCCAGTTTGGAAGAAGTAC
GAAATATGCGCTTATTGACAACGAATTTGCTCAATCTTGCGCGCAGGGAAGATGGCCTGAAGCCTGATTTATCTGAAGTG
GGTCCGGAATTTTTTGAAGATGTTTTTGAAAATTATGGCATTATTGCTGAAGAAAATGGCAAGGAATTGACCGTTACCAA
TCATGTTCATCAATTGGTGAAAACCGATAAGGTTCTTTTAAAACAACTGATGACCATTTTATTTGACAATGCCATGAAAT
ATTCCGATGAAGATGGGAAGATTGAATTGACAGTCTTTATTAAAGACCGCAATCTACACTTGCTTGTTTCTGATAATGGA
ATCGGTATTAGTGCAGAAGATAAGAAGAAAATCTTTGATCGTTTTTATCGAGTTGATAAGGCGCGTACACGCCAAAAAGG
TGGGTTTGGATTGGGCTTATCTCTCGCCAAACAAATTGTACAGTCTTTAAATGGTGATATTCAAGTAAAAAACAACCAAC
CAAAAGGAACTGTTTTTGAAGTGAAATTGCCAAGATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(246-312)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(356-464)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

50.54

99.57

0.503
  ciaH Streptococcus pneumoniae D39

50.54

99.57

0.503
  ciaH Streptococcus pneumoniae R6

50.54

99.57

0.503
  ciaH Streptococcus pneumoniae TIGR4

50.54

99.57

0.503
  ciaH Streptococcus mutans UA159

50.108

99.57

0.499