NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	PWK65_RS01805	Genome accession	NZ_CP118481
Coordinates	339350..339940 (+)	Length	196 a.a.
NCBI ID	WP_002985850.1	Uniprot ID	A0A9X8T4H8
Organism	Streptococcus pyogenes strain 20185322
Function	degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 334350..344940

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PWK65_RS01790 (PWK65_01770)	-	335162..336607 (-)	1446	WP_002990934.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
PWK65_RS01795 (PWK65_01775)	-	336695..338329 (+)	1635	WP_002990932.1	polysaccharide biosynthesis protein	-
PWK65_RS01800 (PWK65_01780)	upp	338497..339126 (+)	630	WP_002985854.1	uracil phosphoribosyltransferase	-
PWK65_RS01805 (PWK65_01785)	clpP	339350..339940 (+)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
PWK65_RS01810 (PWK65_01790)	-	340435..340728 (+)	294	WP_002990928.1	YlbG family protein	-
PWK65_RS01815 (PWK65_01795)	-	340988..342121 (+)	1134	WP_002987950.1	ISAs1-like element IS1548 family transposase	-
PWK65_RS01820 (PWK65_01805)	tmk	342284..342919 (+)	636	WP_002990917.1	dTMP kinase	-
PWK65_RS01825 (PWK65_01810)	-	342937..343812 (+)	876	WP_002990914.1	DNA polymerase III subunit delta'	-
PWK65_RS01830 (PWK65_01815)	-	343937..344071 (+)	135	WP_002990910.1	hypothetical protein	-
PWK65_RS01835 (PWK65_01820)	yabA	344476..344799 (+)	324	WP_002985838.1	DNA replication initiation control protein YabA	-

Sequence

Protein

Download Length: 196 a.a. Molecular weight: 21648.88 Da Isoelectric Point: 5.2834

                                >NTDB_id=792659 PWK65_RS01805 WP_002985850.1 339350..339940(+) (clpP) [Streptococcus pyogenes strain 20185322]

MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN

FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK

TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

Download Length: 591 bp

                                >NTDB_id=792659 PWK65_RS01805 WP_002985850.1 339350..339940(+) (clpP) [Streptococcus pyogenes strain 20185322]

ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT

TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA

ACACTAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC

TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA

AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA

CGGATATGGCTATCGCGGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGAAAA

ACGATTAAACAAATCCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA

TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561

Detailed information NTG0792659