Detailed information NTG0789273

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: PUW70_RS10365
• Genome accession: NZ_CP118029
• Coordinates: 2008183..2009373 (+)
• Length: 396 a.a.
• NCBI ID: WP_024052475.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain VSI68
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2003183..2014373

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW70_RS10340 (PUW70_10340)	comE	2004990..2005739 (-)	750	WP_024052478.1	competence system response regulator transcription factor ComE	Regulator
PUW70_RS10345 (PUW70_10345)	comD/comD2	2005739..2007064 (-)	1326	WP_207047776.1	GHKL domain-containing protein	Regulator
PUW70_RS10350 (PUW70_10350)	-	2007082..2007228 (-)	147	WP_003029519.1	bacteriocin	-
PUW70_RS10360 (PUW70_10360)	rlmH	2007510..2007989 (-)	480	WP_024052476.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
PUW70_RS10365 (PUW70_10365)	htrA	2008183..2009373 (+)	1191	WP_024052475.1	trypsin-like peptidase domain-containing protein	Regulator
PUW70_RS10370 (PUW70_10370)	spo0J	2009428..2010195 (+)	768	WP_070672281.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 41711.71 Da
• Isoelectric Point: 9.4264

>NTDB_id=789273 PUW70_RS10365 WP_024052475.1 2008183..2009373(+) (htrA) [Streptococcus anginosus strain VSI68]
MKNSSNFTKKLLLLFMVLAIGFIGGLLGNLTSSKLSTNSSTTTKVNQVTTAYKNTNSTTQAVSKVKDAVVSVITYANNNS
QNSVFGNDDSNNNNDNSQQVASEGSGVIYKKDGKYAYLVTNTHVISGAKKVDIRLADGNKVPGEIVGSDTYSDISVVRIS
ADKVKSVAEFGDSSKLTVGETAIAIGSPLGSNYANTVTQGIISSLNRNVSLKSEDGQTISTQAIQTDTAINPGNSGGPLV
NIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDVINIINQLEANGTVTRPALGIQMIDITNLSSSDLSRLKLPSKITSGV
VVRSAQSGMPAEGKLQKYDVITKVDDKEIFSTSDLQSALYKHSIGDNIKITFYRDGKETTTTIKLTKSTKDLDSNN

Nucleotide

• Length: 1191 bp

>NTDB_id=789273 PUW70_RS10365 WP_024052475.1 2008183..2009373(+) (htrA) [Streptococcus anginosus strain VSI68]
ATGAAAAACTCTTCAAATTTCACAAAAAAATTGTTATTGCTTTTCATGGTCTTAGCTATAGGTTTTATCGGTGGTTTACT
TGGAAACTTAACTTCATCTAAATTATCAACAAATAGCTCTACAACGACTAAAGTTAATCAAGTTACTACTGCTTATAAAA
ATACAAATTCCACAACACAAGCTGTGAGTAAAGTGAAAGATGCTGTGGTATCCGTTATTACCTATGCTAATAATAATTCA
CAAAACAGCGTGTTTGGAAATGATGATTCAAATAATAACAATGATAATTCTCAACAAGTAGCTAGCGAAGGATCTGGGGT
TATTTATAAAAAAGATGGAAAATACGCTTACTTAGTAACCAATACTCACGTTATCAGTGGTGCTAAAAAAGTTGACATTC
GTTTAGCAGATGGTAATAAAGTTCCTGGAGAAATTGTAGGGTCAGATACTTATTCTGATATCTCCGTTGTTCGAATTAGT
GCTGATAAAGTAAAATCAGTTGCTGAATTTGGAGATTCTAGTAAATTGACGGTTGGTGAGACAGCTATTGCGATTGGAAG
TCCGCTCGGTTCAAATTACGCTAACACTGTGACGCAAGGAATTATTTCTAGTTTAAATCGTAATGTTTCTTTAAAATCTG
AAGACGGACAAACGATTTCAACACAAGCTATTCAAACAGACACAGCTATTAACCCAGGGAACTCTGGTGGACCACTTGTG
AATATCCAAGGACAAGTAATTGGTATTACTTCAAGTAAAATAGCTAGCAACGGCGGAACTTCGGTTGAAGGATTAGGATT
TGCTATTCCATCTAATGATGTTATAAACATTATTAACCAGTTAGAAGCAAATGGAACTGTTACACGACCAGCTCTAGGAA
TCCAAATGATTGACATCACTAATCTGTCTAGTTCAGATCTATCACGCTTAAAACTTCCATCAAAAATAACTAGTGGAGTT
GTCGTACGTTCAGCTCAATCTGGAATGCCAGCTGAAGGAAAACTTCAAAAATATGATGTGATTACAAAAGTAGATGATAA
AGAAATTTTTTCAACAAGTGATTTACAATCCGCTTTATACAAACATTCAATTGGTGACAACATAAAAATCACTTTCTATC
GTGATGGAAAAGAAACTACTACTACCATTAAGCTTACAAAATCTACAAAAGATTTAGATTCAAATAATTGA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

• PDZ domain (PDZ_2) (290-385)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	75.312	100	0.763
htrA	Streptococcus mitis NCTC 12261	72.544	100	0.727
htrA	Streptococcus pneumoniae Rx1	72.292	100	0.725
htrA	Streptococcus pneumoniae D39	72.292	100	0.725
htrA	Streptococcus pneumoniae R6	72.292	100	0.725
htrA	Streptococcus pneumoniae TIGR4	72.292	100	0.725
htrA	Streptococcus mutans UA159	55.471	99.242	0.551