Detailed information NTG0788150

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: Q6379_RS04850
• Genome accession: NZ_CP130892
• Coordinates: 913669..914700 (+)
• Length: 343 a.a.
• NCBI ID: WP_003691202.1
• Uniprot ID: Q5F8L2
• Organism: Neisseria gonorrhoeae strain NJ204705
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 908669..919700

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q6379_RS04830 (Q6379_04830)	-	909397..909771 (-)	375	WP_003688664.1	arsenate reductase	-
Q6379_RS04835 (Q6379_04835)	-	909921..911549 (+)	1629	WP_010951119.1	ABC-F family ATPase	-
Q6379_RS04840 (Q6379_04840)	-	911628..912860 (+)	1233	WP_003701338.1	multifunctional CCA addition/repair protein	-
Q6379_RS04845 (Q6379_04845)	-	913279..913587 (+)	309	WP_003688671.1	hypothetical protein	-
Q6379_RS04850 (Q6379_04850)	ruvB	913669..914700 (+)	1032	WP_003691202.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
Q6379_RS04855 (Q6379_04855)	rpe	914945..915628 (-)	684	WP_003688675.1	ribulose-phosphate 3-epimerase	-
Q6379_RS04860 (Q6379_04860)	-	915774..916208 (+)	435	WP_003688677.1	Spy/CpxP family protein refolding chaperone	-
Q6379_RS04865 (Q6379_04865)	-	916221..917084 (-)	864	WP_003693081.1	ATP-binding protein	-
Q6379_RS04870 (Q6379_04870)	-	917092..917709 (-)	618	WP_010358100.1	riboflavin synthase	-
Q6379_RS04875 (Q6379_04875)	-	917872..918486 (-)	615	WP_003691204.1	molybdenum cofactor guanylyltransferase	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37638.23 Da
• Isoelectric Point: 5.4704

>NTDB_id=788150 Q6379_RS04850 WP_003691202.1 913669..914700(+) (ruvB) [Neisseria gonorrhoeae strain NJ204705]
MLQTDNLTAAQPQRIVAAQTASAQEELLERALRPKTLDDYIGQHKAKEQLAIFIQAAKKRGEALDHVLLFGPPGLGKTTL
AHIIAKELGVNLRQTSGPVLERAGDLAALLTNLDPHDVLFIDEIHRLSPVVEEILYPALEDYRLDIMIGEGPAARSVKID
LPPFTLVGATTRAGMLTNPLRDRFGIVSRLEFYENRDLTTIVSRSAQLLQLDMGEEGAMEVAKRSRGTPRIANRLLRRVR
DFADVKNNGVIDAAVADAALSMLDVDAQGLDVMDRKFLEAVLHKFGGGPVGLDNVAAAIGESTDTIEDVIEPYLIQQGFL
QRTPRGRMATERAYLHFGLPVEK

Nucleotide

• Length: 1032 bp

>NTDB_id=788150 Q6379_RS04850 WP_003691202.1 913669..914700(+) (ruvB) [Neisseria gonorrhoeae strain NJ204705]
ATGCTGCAAACCGACAACCTGACCGCCGCGCAACCGCAACGCATCGTTGCCGCCCAAACCGCCTCCGCACAGGAAGAACT
GCTCGAACGCGCCCTCCGCCCCAAAACGCTGGACGACTACATCGGGCAGCATAAAGCCAAAGAGCAGCTCGCCATCTTCA
TCCAAGCCGCCAAAAAACGCGGCGAAGCACTCGACCACGTCCTGCTTTTCGGCCCGCCCGGACTGGGCAAAACCACCCTT
GCCCACATCATCGCCAAAGAGTTGGGCGTAAATTTGCGCCAAACCAGCGGCCCCGTCCTCGAACGCGCCGGCGACCTCGC
CGCCCTTTTGACCAACCTTGATCCGCACGACGTATTGTTTATCGACGAAATCCACCGGCTAAGCCCCGTCGTCGAGGAAA
TCCTCTATCCCGCGCTCGAAGACTACCGGCTCGACATTATGATAGGCGAAGGACCCGCCGCACGTTCCGTCAAAATCGAC
CTGCCGCCCTTCACCCTCGTCGGCGCGACCACCCGCGCCGGTATGCTGACCAACCCGTTGCGCGACCGCTTCGGCATCGT
CTCCCGCCTCGAGTTTTACGAAAACCGCGACCTTACCACCATCGTCAGCCGTTCGGCACAACTGTTGCAGCTCGATATGG
GCGAAGAAGGCGCGATGGAAGTCGCCAAACGCAGCCGCGGCACGCCCCGCATCGCCAACCGCCTGTTGCGCCGCGTGCGC
GATTTCGCCGACGTGAAAAACAACGGCGTAATCGATGCCGCCGTCGCCGATGCCGCTTTAAGTATGCTGGACGTGGACGC
GCAGGGGCTGGACGTGATGGACAGGAAATTCCTCGAAGCCGTTTTGCACAAATTCGGCGGCGGCCCCGTCGGTTTGGACA
ACGTTGCCGCCGCCATCGGCGAATCTACGGACACCATCGAAGACGTTATCGAACCCTACCTCATCCAACAAGGCTTTTTG
CAACGCACCCCGCGCGGCAGGATGGCGACCGAACGCGCCTACCTGCATTTCGGGCTGCCCGTCGAAAAATAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (268-337)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (32-190)

• RuvB AAA lid domain (AAA_lid_4) (193-266)

3D structure

• AlphaFold DB: Q5F8L2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Bacillus subtilis subsp. subtilis str. 168	60.55	95.335	0.577
ruvB	Streptococcus pneumoniae TIGR4	62.739	91.545	0.574
ruvB	Streptococcus pneumoniae R6	62.739	91.545	0.574
ruvB	Streptococcus pneumoniae D39	62.739	91.545	0.574
ruvB	Synechocystis sp. PCC 6803	54.268	95.627	0.519
ruvB	Helicobacter pylori 26695	56.55	91.254	0.516