Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   PQ615_RS09155 Genome accession   NZ_CP117058
Coordinates   1883579..1884316 (-) Length   245 a.a.
NCBI ID   WP_003100196.1    Uniprot ID   A0A3L8GEB0
Organism   Streptococcus iniae strain LSSM211007SI     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1878579..1889316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQ615_RS09135 (PQ615_09135) - 1879290..1880102 (-) 813 WP_016356177.1 YidC/Oxa1 family membrane protein insertase -
  PQ615_RS09140 (PQ615_09140) rnpA 1880086..1880445 (-) 360 WP_003100192.1 ribonuclease P protein component -
  PQ615_RS09145 (PQ615_09145) argH 1880533..1881915 (-) 1383 WP_003100193.1 argininosuccinate lyase -
  PQ615_RS09150 (PQ615_09150) - 1881941..1883140 (-) 1200 WP_003100195.1 argininosuccinate synthase -
  PQ615_RS09155 (PQ615_09155) comE/blpR 1883579..1884316 (-) 738 WP_003100196.1 LytTR family DNA-binding domain-containing protein Regulator
  PQ615_RS09160 (PQ615_09160) - 1884320..1885627 (-) 1308 WP_003100197.1 GHKL domain-containing protein -
  PQ615_RS09165 (PQ615_09165) - 1885628..1886974 (-) 1347 WP_003100198.1 sensor histidine kinase -
  PQ615_RS09170 (PQ615_09170) - 1887107..1888423 (-) 1317 WP_064537882.1 GHKL domain-containing protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28862.07 Da        Isoelectric Point: 4.9728

>NTDB_id=782463 PQ615_RS09155 WP_003100196.1 1883579..1884316(-) (comE/blpR) [Streptococcus iniae strain LSSM211007SI]
MNIFILEDNFIQQTRIESTIEEILAETGINCNQLEIFSNPDKLYDAILEKGNHQLFFLDIEIKNEQKKGLELATKIRQRD
ANAVIVFVTTHSEFAPISFKYKVSALDFIDKAVDKQQFKEQIEECIQYTSKMMESHEPEEFFIFETAQTKLRLPFKDILY
FATSTTPHKVCLWTQTERLEFYGNLSEIQEAAPKLFMCHRSYLINLANVVRIDKYEQLVYFENGDSCPVSRLKIKHLIEK
WEELH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=782463 PQ615_RS09155 WP_003100196.1 1883579..1884316(-) (comE/blpR) [Streptococcus iniae strain LSSM211007SI]
ATGAATATATTTATCCTTGAAGACAATTTTATCCAGCAAACGCGAATAGAGTCCACCATTGAAGAAATATTGGCAGAGAC
AGGTATTAACTGTAATCAATTGGAAATTTTTTCCAATCCAGATAAATTGTATGATGCGATTTTGGAAAAGGGCAATCACC
AATTGTTCTTTTTAGACATTGAAATCAAGAACGAGCAAAAAAAAGGCTTGGAGTTAGCCACAAAAATTAGGCAAAGAGAT
GCTAATGCAGTCATTGTATTTGTTACCACACATTCAGAATTTGCTCCGATTTCGTTTAAGTATAAAGTTTCTGCCCTTGA
TTTTATTGACAAGGCGGTTGATAAACAACAGTTTAAGGAACAAATCGAAGAATGTATTCAGTACACCAGCAAAATGATGG
AGAGTCATGAACCTGAAGAATTCTTTATTTTTGAGACAGCTCAGACAAAACTACGTCTGCCTTTTAAAGATATTTTATAT
TTTGCAACCTCAACCACACCTCATAAAGTGTGTTTATGGACACAAACAGAAAGGTTGGAATTTTATGGCAACCTGTCGGA
AATTCAAGAAGCAGCACCTAAGCTTTTTATGTGCCATCGCTCCTACTTGATTAATTTAGCCAATGTGGTTCGTATTGATA
AATATGAGCAATTGGTTTATTTTGAAAATGGCGATTCCTGTCCAGTTTCTCGTCTTAAAATAAAGCATTTGATTGAGAAA
TGGGAAGAATTGCATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(152-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L8GEB0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

51.681

97.143

0.502
  comE/comE2 Streptococcus equinus JB1

44.672

99.592

0.445
  comE/comE1 Streptococcus equinus JB1

44.538

97.143

0.433
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

40.329

99.184

0.4
  comE/comE2 Streptococcus gordonii strain NCTC7865

40.329

99.184

0.4
  comE Streptococcus pneumoniae Rx1

36.475

99.592

0.363
  comE Streptococcus pneumoniae D39

36.475

99.592

0.363
  comE Streptococcus pneumoniae R6

36.475

99.592

0.363
  comE Streptococcus pneumoniae TIGR4

36.475

99.592

0.363