Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   PO908_RS04250 Genome accession   NZ_CP117042
Coordinates   786243..786944 (+) Length   233 a.a.
NCBI ID   WP_021001531.1    Uniprot ID   A0A0P0N857
Organism   Streptococcus anginosus strain CGMH_KH1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 781243..791944
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PO908_RS04230 (PO908_04210) ccpA 782088..783092 (+) 1005 WP_022526272.1 catabolite control protein A Regulator
  PO908_RS04235 (PO908_04215) - 783272..784270 (+) 999 WP_021001528.1 glycosyltransferase family 4 protein -
  PO908_RS04240 (PO908_04220) - 784272..785585 (+) 1314 WP_057489614.1 glycosyltransferase family 4 protein -
  PO908_RS04245 (PO908_04225) - 785612..785953 (+) 342 WP_021001530.1 hypothetical protein -
  PO908_RS04250 (PO908_04230) micA 786243..786944 (+) 702 WP_021001531.1 response regulator YycF Regulator
  PO908_RS04255 (PO908_04235) micB 786937..788289 (+) 1353 WP_394468113.1 cell wall metabolism sensor histidine kinase VicK Regulator
  PO908_RS04260 (PO908_04240) vicX 788292..789095 (+) 804 WP_021001533.1 MBL fold metallo-hydrolase Regulator
  PO908_RS04265 (PO908_04245) - 789104..789464 (+) 361 Protein_800 YbaN family protein -
  PO908_RS04270 (PO908_04250) rnc 789846..790544 (+) 699 WP_021001534.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26869.83 Da        Isoelectric Point: 4.6824

>NTDB_id=782248 PO908_RS04250 WP_021001531.1 786243..786944(+) (micA) [Streptococcus anginosus strain CGMH_KH1]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=782248 PO908_RS04250 WP_021001531.1 786243..786944(+) (micA) [Streptococcus anginosus strain CGMH_KH1]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCGATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACTGCCTTCGACGGTCGCGAAGCGTTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAACTGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGCAATGTTCCCATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGATAAAGTCATTGGTCTCGAAATTGGAGCAGATGACTATATGACAAAGCCGTTTTCTAATCGTGA
GTTACAGGCGCGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AGATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTAGATTTAACACAC
CGTGAGTTTGAATTGCTACACCATTTGGCCACGCATATCGGGCAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTGACAATTCGTCGTTTGAGAGAAAAGATAGAGGATATTCCTA
GCCGACCAGAGTACATTTTAACGCGGCGCGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0P0N857

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.833

100

0.828
  vicR Streptococcus mutans UA159

79.661

100

0.807
  covR Streptococcus salivarius strain HSISS4

44.783

98.712

0.442
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.978

98.283

0.442
  scnR Streptococcus mutans UA159

36.052

100

0.361