NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	PO908_RS03180	Genome accession	NZ_CP117042
Coordinates	566441..567055 (+)	Length	204 a.a.
NCBI ID	WP_223349572.1	Uniprot ID	-
Organism	Streptococcus anginosus strain CGMH_KH1
Function	degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 561441..572055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PO908_RS03170 (PO908_03155)	mgtA	562972..565626 (+)	2655	WP_394468088.1	magnesium-translocating P-type ATPase	-
PO908_RS03175 (PO908_03160)	upp	565724..566353 (+)	630	WP_003025639.1	uracil phosphoribosyltransferase	-
PO908_RS03180 (PO908_03165)	clpP	566441..567055 (+)	615	WP_223349572.1	ATP-dependent Clp protease proteolytic subunit	Regulator
PO908_RS03185 (PO908_03170)	-	567147..567416 (+)	270	WP_003025630.1	DUF2129 domain-containing protein	-
PO908_RS03190 (PO908_03175)	-	567499..568662 (+)	1164	WP_003025628.1	ABC transporter substrate-binding protein	-
PO908_RS03195 (PO908_03180)	-	569050..569919 (+)	870	WP_024052038.1	branched-chain amino acid ABC transporter permease	-
PO908_RS03200 (PO908_03185)	-	569923..570873 (+)	951	WP_021001401.1	branched-chain amino acid ABC transporter permease	-
PO908_RS03205 (PO908_03190)	-	570873..571637 (+)	765	WP_021001402.1	ABC transporter ATP-binding protein	-

Sequence

Protein

Download Length: 204 a.a. Molecular weight: 22503.62 Da Isoelectric Point: 4.6199

                                >NTDB_id=782239 PO908_RS03180 WP_223349572.1 566441..567055(+) (clpP) [Streptococcus anginosus strain CGMH_KH1]

MSDEKENTMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINTPGGSVSAG

LAIVDTMNFIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGSGTQQTDMAIAAEHLLKTRNNLEK

ILADNSGKTIKQVHKDAERDYWMSAQETLDYGFIDEIMANNNLN

Nucleotide

Download Length: 615 bp

                                >NTDB_id=782239 PO908_RS03180 WP_223349572.1 566441..567055(+) (clpP) [Streptococcus anginosus strain CGMH_KH1]

ATATCAGATGAAAAGGAGAATACAATGATTCCTGTAGTTATTGAACAAACAAGTCGTGGGGAACGTTCCTACGATATTTA

CTCACGCTTATTAAAAGATCGCATTATTATGCTGACAGGTCCTGTTGAGGACAATATGGCTAATTCTATTATTGCGCAAT

TGCTTTTCCTTGATGCACAAGATAATACTAAAGATATTTATCTTTACATCAATACGCCAGGAGGTTCTGTATCGGCGGGT

CTAGCGATTGTCGATACCATGAACTTCATCAAATCAGATGTTCAAACAATTGTCATGGGGATGGCTGCTTCCATGGGAAC

TATTATTGCTTCAAGCGGTGCTAAAGGCAAACGCTTCATGTTGCCGAATGCAGAATACTTGATTCACCAACCAATGGGTG

GAACTGGTAGCGGTACGCAACAAACCGATATGGCGATTGCAGCTGAGCATTTGCTGAAAACTCGGAATAACTTGGAGAAA

ATCCTTGCGGATAATTCAGGGAAAACCATTAAGCAAGTACATAAAGACGCAGAACGCGATTATTGGATGAGCGCTCAAGA

AACCTTGGATTATGGTTTCATTGATGAAATTATGGCAAATAATAATTTAAACTAG

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(19-200)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Streptococcus mutans UA159	89.655	99.51	0.892
clpP	Streptococcus thermophilus LMD-9	92.308	95.588	0.882
clpP	Streptococcus thermophilus LMG 18311	92.308	95.588	0.882
clpP	Streptococcus pyogenes JRS4	91.795	95.588	0.877
clpP	Streptococcus pyogenes MGAS315	91.795	95.588	0.877
clpP	Streptococcus pneumoniae D39	90.816	96.078	0.873
clpP	Streptococcus pneumoniae Rx1	90.816	96.078	0.873
clpP	Streptococcus pneumoniae R6	90.816	96.078	0.873
clpP	Streptococcus pneumoniae TIGR4	90.816	96.078	0.873
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.667	95.588	0.828
clpP	Lactococcus lactis subsp. cremoris KW2	86.154	95.588	0.824
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	94.608	0.539
clpP	Bacillus subtilis subsp. subtilis str. 168	56.25	94.118	0.529

Detailed information NTG0782239