Detailed information NTG0781693

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: M0P28_RS05630
• Genome accession: NZ_CP116958
• Coordinates: 1087749..1088591 (-)
• Length: 280 a.a.
• NCBI ID: WP_003064756.1
• Uniprot ID: E0PDM2
• Organism: Streptococcus pasteurianus strain WUSP074
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1082749..1093591

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M0P28_RS05610 (M0P28_05610)	-	1083196..1083678 (-)	483	WP_003064748.1	hypothetical protein	-
M0P28_RS05615 (M0P28_05615)	-	1083695..1084418 (-)	724	Protein_1046	DUF3307 domain-containing protein	-
M0P28_RS05620 (M0P28_05620)	-	1084418..1085083 (-)	666	WP_003064752.1	SatD family protein	-
M0P28_RS05625 (M0P28_05625)	topA	1085231..1087372 (-)	2142	WP_048791149.1	type I DNA topoisomerase	-
M0P28_RS05630 (M0P28_05630)	dprA	1087749..1088591 (-)	843	WP_003064756.1	DNA-processing protein DprA	Machinery gene
M0P28_RS05635 (M0P28_05635)	-	1088666..1089217 (-)	552	WP_003064760.1	sugar O-acetyltransferase	-
M0P28_RS05640 (M0P28_05640)	-	1089219..1089998 (-)	780	WP_013851825.1	ribonuclease HII	-
M0P28_RS05645 (M0P28_05645)	ylqF	1089985..1090839 (-)	855	WP_003064765.1	ribosome biogenesis GTPase YlqF	-
M0P28_RS05650 (M0P28_05650)	-	1090934..1092442 (-)	1509	WP_106474485.1	tyrosine-type recombinase/integrase	-
M0P28_RS05655 (M0P28_05655)	-	1092530..1092763 (-)	234	WP_047210205.1	hypothetical protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31027.10 Da
• Isoelectric Point: 8.3615

>NTDB_id=781693 M0P28_RS05630 WP_003064756.1 1087749..1088591(-) (dprA) [Streptococcus pasteurianus strain WUSP074]
MNNFELFKLKKAGLTNLNILAILDYQEKQEKSLSLRNMAVVSKCKNPILFMEKYKALDIKELRKEFNCFPSVSILDDEYP
LELKHCYNPPVLLFYQGNLELLNRPKMAVVGARTASATGTKSVQKIVKELGNHFVIVSGLARGIDTSAHLSSLKNGGASI
AVIGCGLDVYYPKENKQLQEYMVKNHLVLSEYVAGEAPLKFHFPERNRIIAGLSQGVIVVEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCVTSGLDILSEYQI

Nucleotide

• Length: 843 bp

>NTDB_id=781693 M0P28_RS05630 WP_003064756.1 1087749..1088591(-) (dprA) [Streptococcus pasteurianus strain WUSP074]
ATGAATAATTTTGAATTGTTTAAATTAAAAAAAGCAGGATTAACAAATCTTAATATTTTAGCTATTTTGGATTATCAAGA
AAAGCAAGAGAAATCACTATCTTTGCGTAATATGGCAGTCGTCTCAAAATGTAAAAATCCTATCCTTTTTATGGAAAAAT
ACAAAGCACTGGACATCAAAGAATTGCGCAAAGAATTTAATTGTTTTCCTAGTGTTTCCATACTAGATGACGAATACCCA
TTAGAACTCAAACATTGTTATAATCCACCTGTTTTGCTGTTTTATCAAGGAAATTTAGAATTACTCAATCGCCCAAAAAT
GGCAGTAGTAGGAGCAAGAACAGCATCAGCAACAGGGACAAAATCCGTACAGAAAATTGTCAAAGAACTCGGGAATCATT
TTGTTATCGTTAGTGGGTTGGCGCGTGGCATTGATACCAGTGCGCATTTATCATCTCTAAAAAACGGTGGTGCATCGATT
GCCGTTATCGGTTGTGGACTGGACGTTTATTATCCCAAAGAAAATAAGCAGTTGCAGGAGTACATGGTTAAAAATCACCT
CGTATTAAGTGAGTACGTAGCAGGAGAAGCACCGCTGAAATTCCATTTTCCAGAGCGAAATCGTATTATTGCAGGTTTAT
CACAAGGCGTTATCGTAGTAGAAGCTAAGCTGCGCTCAGGCAGTTTGATTACGTGCGAAAGAGCATTGGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGAAATATTTTAGATGGAAAATCTGATGGCTGTCATCATTTGATAAAAGAGGGCGCAAAATG
CGTCACATCAGGCTTAGATATCCTTTCGGAATATCAAATATAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

3D structure

• AlphaFold DB: E0PDM2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	74.46	99.286	0.739
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.929	100	0.639
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.929	100	0.639
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.929	100	0.639
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.929	100	0.639
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.929	100	0.639
dprA/cilB/dalA	Streptococcus mitis SK321	63.929	100	0.639
dprA	Lactococcus lactis subsp. cremoris KW2	61.871	99.286	0.614
dprA	Legionella pneumophila strain ERS1305867	42.739	86.071	0.368
dprA	Haemophilus influenzae Rd KW20	38.258	94.286	0.361