Detailed information
Overview
| Name | prx | Type | Regulator |
| Locus tag | POF63_RS03600 | Genome accession | NZ_CP116708 |
| Coordinates | 641051..641239 (+) | Length | 62 a.a. |
| NCBI ID | WP_000027835.1 | Uniprot ID | A0AAV3JNT7 |
| Organism | Streptococcus agalactiae strain CNCTC 10/84 sCas9 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 632264..641009 | 641051..641239 | flank | 42 |
| IS/Tn | 639984..640595 | 641051..641239 | flank | 456 |
Gene organization within MGE regions
Location: 632264..641239
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| POF63_RS03560 (POF63_03560) | - | 633643..633804 (-) | 162 | WP_000508795.1 | NINE protein | - |
| POF63_RS03565 (POF63_03565) | - | 634547..635824 (+) | 1278 | WP_000594360.1 | ABC transporter permease | - |
| POF63_RS03570 (POF63_03570) | - | 635834..636490 (+) | 657 | WP_000353149.1 | ABC transporter ATP-binding protein | - |
| POF63_RS03575 (POF63_03575) | - | 636490..637866 (+) | 1377 | WP_000594351.1 | FtsX-like permease family protein | - |
| POF63_RS03580 (POF63_03580) | - | 637963..638616 (+) | 654 | WP_000699093.1 | response regulator transcription factor | - |
| POF63_RS03585 (POF63_03585) | - | 638613..639932 (+) | 1320 | WP_000734169.1 | HAMP domain-containing sensor histidine kinase | - |
| POF63_RS03590 (POF63_03590) | - | 639984..640631 (-) | 648 | Protein_625 | IS3 family transposase | - |
| POF63_RS03595 (POF63_03595) | - | 640809..641009 (+) | 201 | WP_000076708.1 | CsbD family protein | - |
| POF63_RS03600 (POF63_03600) | prx | 641051..641239 (+) | 189 | WP_000027835.1 | hypothetical protein | Regulator |
Sequence
Protein
Download Length: 62 a.a. Molecular weight: 7180.25 Da Isoelectric Point: 4.7815
>NTDB_id=779313 POF63_RS03600 WP_000027835.1 641051..641239(+) (prx) [Streptococcus agalactiae strain CNCTC 10/84 sCas9]
MSIRTDIDEFKEAIDKGYISGNTVAIVRKNGKIFDYVLLHEEVREEEVVTVERVLDVLRKLS
MSIRTDIDEFKEAIDKGYISGNTVAIVRKNGKIFDYVLLHEEVREEEVVTVERVLDVLRKLS
Nucleotide
Download Length: 189 bp
>NTDB_id=779313 POF63_RS03600 WP_000027835.1 641051..641239(+) (prx) [Streptococcus agalactiae strain CNCTC 10/84 sCas9]
TTGTCTATCAGAACAGATATAGATGAGTTTAAAGAAGCGATTGATAAAGGCTATATTTCAGGGAACACAGTAGCGATAGT
GCGTAAAAACGGAAAGATATTTGATTATGTGTTACTACACGAAGAAGTGAGAGAAGAAGAGGTTGTTACAGTTGAGAGAG
TGCTTGATGTACTGAGGAAGTTATCATAA
TTGTCTATCAGAACAGATATAGATGAGTTTAAAGAAGCGATTGATAAAGGCTATATTTCAGGGAACACAGTAGCGATAGT
GCGTAAAAACGGAAAGATATTTGATTATGTGTTACTACACGAAGAAGTGAGAGAAGAAGAGGTTGTTACAGTTGAGAGAG
TGCTTGATGTACTGAGGAAGTTATCATAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
72.222 |
87.097 |
0.629 |
| prx | Streptococcus pyogenes MGAS8232 |
69.091 |
88.71 |
0.613 |
| prx | Streptococcus pyogenes MGAS315 |
66.667 |
87.097 |
0.581 |
| prx | Streptococcus pyogenes MGAS315 |
85 |
64.516 |
0.548 |
| prx | Streptococcus pyogenes MGAS315 |
61.818 |
88.71 |
0.548 |
| prx | Streptococcus pyogenes MGAS315 |
74.359 |
62.903 |
0.468 |
| prx | Streptococcus pyogenes MGAS315 |
78.378 |
59.677 |
0.468 |