Detailed information NTG0777102

Bioinformatically predicted

Overview

• Name: micA
• Type: Regulator
• Locus tag: PFZ59_RS07030
• Genome accession: NZ_CP116393
• Coordinates: 1378720..1379424 (+)
• Length: 234 a.a.
• NCBI ID: WP_208581972.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SS/UPM/MY/F001
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1373720..1384424

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PFZ59_RS06995 (PFZ59_06995)	-	1373764..1374093 (+)	330	WP_277696633.1	IS630 transposase-related protein	-
PFZ59_RS07000 (PFZ59_07000)	-	1374167..1374613 (+)	447	WP_277697757.1	transposase	-
PFZ59_RS07005 (PFZ59_07005)	-	1374619..1375482 (+)	864	WP_277696689.1	hypothetical protein	-
PFZ59_RS07010 (PFZ59_07010)	-	1375528..1376187 (-)	660	WP_208581969.1	amino acid ABC transporter permease	-
PFZ59_RS07015 (PFZ59_07015)	-	1376202..1376900 (-)	699	WP_063077049.1	amino acid ABC transporter permease	-
PFZ59_RS07020 (PFZ59_07020)	-	1376915..1377754 (-)	840	WP_277696690.1	transporter substrate-binding domain-containing protein	-
PFZ59_RS07025 (PFZ59_07025)	-	1377765..1378526 (-)	762	WP_277696691.1	amino acid ABC transporter ATP-binding protein	-
PFZ59_RS07030 (PFZ59_07030)	micA	1378720..1379424 (+)	705	WP_208581972.1	response regulator YycF	Regulator
PFZ59_RS07035 (PFZ59_07035)	micB	1379417..1380766 (+)	1350	WP_277696692.1	cell wall metabolism sensor histidine kinase VicK	Regulator
PFZ59_RS07040 (PFZ59_07040)	vicX	1380773..1381576 (+)	804	WP_277696693.1	MBL fold metallo-hydrolase	Regulator
PFZ59_RS07045 (PFZ59_07045)	-	1381686..1382690 (+)	1005	WP_277696681.1	IS5 family transposase	-
PFZ59_RS07050 (PFZ59_07050)	-	1383139..1383513 (+)	375	WP_228476612.1	ATP-binding cassette domain-containing protein	-

Sequence

Protein

• Length: 234 a.a.
• Molecular weight: 26793.83 Da
• Isoelectric Point: 4.8957

>NTDB_id=777102 PFZ59_RS07030 WP_208581972.1 1378720..1379424(+) (micA) [Streptococcus suis strain SS/UPM/MY/F001]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQINIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide

• Length: 705 bp

>NTDB_id=777102 PFZ59_RS07030 WP_208581972.1 1378720..1379424(+) (micA) [Streptococcus suis strain SS/UPM/MY/F001]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATAGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGATAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATTTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (154-229)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micA	Streptococcus pneumoniae Cp1015	81.974	99.573	0.816
vicR	Streptococcus mutans UA159	80.426	100	0.808
covR	Lactococcus lactis subsp. lactis strain DGCC12653	44.783	98.291	0.44
covR	Streptococcus salivarius strain HSISS4	44.156	98.718	0.436
scnR	Streptococcus mutans UA159	37.975	100	0.385