Detailed information NTG0777103

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: PFZ59_RS07035
• Genome accession: NZ_CP116393
• Coordinates: 1379417..1380766 (+)
• Length: 449 a.a.
• NCBI ID: WP_277696692.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SS/UPM/MY/F001
• Function: repress competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1381686..1382690	1379417..1380766	flank	920

Gene organization within MGE regions

Location: 1379417..1382690

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PFZ59_RS07035 (PFZ59_07035)	micB	1379417..1380766 (+)	1350	WP_277696692.1	cell wall metabolism sensor histidine kinase VicK	Regulator
PFZ59_RS07040 (PFZ59_07040)	vicX	1380773..1381576 (+)	804	WP_277696693.1	MBL fold metallo-hydrolase	Regulator
PFZ59_RS07045 (PFZ59_07045)	-	1381686..1382690 (+)	1005	WP_277696681.1	IS5 family transposase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51093.17 Da
• Isoelectric Point: 4.5562

>NTDB_id=777103 PFZ59_RS07035 WP_277696692.1 1379417..1380766(+) (micB) [Streptococcus suis strain SS/UPM/MY/F001]
MINRLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNTDSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide

• Length: 1350 bp

>NTDB_id=777103 PFZ59_RS07035 WP_277696692.1 1379417..1380766(+) (micB) [Streptococcus suis strain SS/UPM/MY/F001]
ATGATTAATCGATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
AACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATAACAGATATGGCTAATTCCCTCAATGATTTGTCCGAG
GTTATCCGCTTAACTCACGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAGCGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTCAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTTGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATACTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGCCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAGCATAAGGGTTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (96-199)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	70.183	97.105	0.682
vicK	Streptococcus mutans UA159	70.72	89.755	0.635