NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	PF977_RS03355	Genome accession	NZ_CP116012
Coordinates	655063..655656 (-)	Length	197 a.a.
NCBI ID	WP_003228214.1	Uniprot ID	A0A199WEF2
Organism	Bacillus subtilis strain SRCM124333
Function	degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 650063..660656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PF977_RS03340 (PF977_03340)	mdxK	650378..652651 (+)	2274	WP_015714760.1	maltose phosphorylase	-
PF977_RS03345 (PF977_03345)	malL	652644..654329 (+)	1686	WP_015714759.1	oligo-1,6-glucosidase	-
PF977_RS03350 (PF977_03350)	pgmB	654326..655000 (+)	675	WP_015714758.1	beta-phosphoglucomutase	-
PF977_RS03355 (PF977_03355)	clpP	655063..655656 (-)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
PF977_RS03365 (PF977_03365)	cotR	656285..657247 (-)	963	WP_015251166.1	sporulation hydrolase CotR	-
PF977_RS03370 (PF977_03370)	cotNP	657603..658946 (+)	1344	WP_003228217.1	FAD-binding oxidoreductase	-
PF977_RS03375 (PF977_03375)	yvdQ	659198..659710 (+)	513	WP_003243249.1	DUF3231 family protein	-
PF977_RS03380 (PF977_03380)	psmB	659746..660066 (-)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
PF977_RS03385 (PF977_03385)	psmA	660066..660401 (-)	336	WP_015714757.1	SMR family transporter	-

Sequence

Protein

Download Length: 197 a.a. Molecular weight: 21682.00 Da Isoelectric Point: 4.9416

                                >NTDB_id=775085 PF977_RS03355 WP_003228214.1 655063..655656(-) (clpP) [Bacillus subtilis strain SRCM124333]

MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT

MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ

PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

Download Length: 594 bp

                                >NTDB_id=775085 PF977_RS03355 WP_003228214.1 655063..655656(-) (clpP) [Bacillus subtilis strain SRCM124333]

ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA

TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG

AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC

ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG

CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAAGCGA

CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGTGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG

CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA

CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A199WEF2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538

Detailed information NTG0775085