Detailed information    

insolico Bioinformatically predicted

Overview

Name   spo0A   Type   Regulator
Locus tag   PF975_RS08110 Genome accession   NZ_CP116010
Coordinates   1582466..1583266 (+) Length   266 a.a.
NCBI ID   WP_003153177.1    Uniprot ID   I2C7K5
Organism   Bacillus velezensis strain SRCM123815     
Function   activation and repression of comK; repression of rok; repression of abrB (predicted from homology)   
Competence regulation

Genomic Context

Location: 1577466..1588266
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PF975_RS08090 (PF975_08090) - 1577588..1578433 (+) 846 WP_021494303.1 TlyA family RNA methyltransferase -
  PF975_RS08095 (PF975_08095) ahrC 1578530..1578979 (+) 450 WP_003153173.1 transcriptional regulator AhrC/ArgR -
  PF975_RS08100 (PF975_08100) recN 1579011..1580741 (+) 1731 WP_007408359.1 DNA repair protein RecN Machinery gene
  PF975_RS08105 (PF975_08105) spoIVB 1580905..1582185 (+) 1281 WP_014418352.1 SpoIVB peptidase -
  PF975_RS08110 (PF975_08110) spo0A 1582466..1583266 (+) 801 WP_003153177.1 sporulation transcription factor Spo0A Regulator
  PF975_RS08115 (PF975_08115) alr 1583413..1584594 (-) 1182 WP_007408361.1 alanine racemase -
  PF975_RS08120 (PF975_08120) - 1584771..1584983 (-) 213 WP_014418351.1 spore germination protein -
  PF975_RS08125 (PF975_08125) - 1585108..1585320 (-) 213 WP_029973891.1 spore germination protein -
  PF975_RS08130 (PF975_08130) - 1585447..1586565 (-) 1119 WP_032863662.1 NADH-dependent flavin oxidoreductase -
  PF975_RS08135 (PF975_08135) - 1586659..1586796 (-) 138 WP_014470646.1 hypothetical protein -
  PF975_RS08140 (PF975_08140) - 1587087..1587719 (-) 633 WP_014418348.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 266 a.a.        Molecular weight: 29630.11 Da        Isoelectric Point: 6.1630

>NTDB_id=774963 PF975_RS08110 WP_003153177.1 1582466..1583266(+) (spo0A) [Bacillus velezensis strain SRCM123815]
MEKIKVCVADDNRELVSLLSEYIEGQDDMEVIGVAYNGQECLSLFKDKNPDVLVLDIIMPHLDGLAVLERLRESELEKQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNVSSVTHRAPSAQSSIIRSQPEPKRKNLDASITSII
HEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVS
MTKAKPTNSEFIAMVADKLRLEHKAS

Nucleotide


Download         Length: 801 bp        

>NTDB_id=774963 PF975_RS08110 WP_003153177.1 1582466..1583266(+) (spo0A) [Bacillus velezensis strain SRCM123815]
GTGGAGAAAATTAAAGTTTGTGTTGCTGATGATAATCGAGAGCTTGTAAGCCTGTTGAGTGAATATATAGAGGGACAGGA
TGATATGGAAGTGATCGGCGTTGCTTATAACGGACAGGAATGTCTTTCTTTGTTTAAAGATAAGAATCCTGATGTACTCG
TTTTAGACATTATCATGCCGCATCTGGACGGACTTGCGGTTTTGGAGCGTCTGCGGGAATCAGAGCTCGAGAAGCAGCCG
AACGTCATCATGCTGACGGCATTCGGTCAGGAAGACGTTACGAAAAAAGCCGTCGATTTAGGCGCGTCCTATTTCATCCT
GAAGCCGTTTGATATGGAAAACCTTGTCGGCCATATCCGCCAGGTAAGCGGAAATGTCAGCAGTGTCACACACCGTGCGC
CGTCCGCGCAAAGCAGCATTATCCGCAGCCAGCCGGAGCCGAAGCGGAAAAATCTCGATGCCAGCATTACAAGCATTATC
CATGAGATCGGTGTGCCTGCCCATATCAAAGGCTATCTTTATTTGCGTGAAGCCATTTCCATGGTGTATAACGATATTGA
ACTCCTCGGCAGCATCACAAAAGTCCTTTATCCCGACATCGCCAAAAAATTCAACACGACCGCAAGCCGTGTAGAACGGG
CCATCCGCCACGCCATTGAAGTCGCATGGAGCAGGGGAAATATTGATTCCATCTCTTCACTGTTCGGATATACGGTAAGC
ATGACAAAAGCAAAACCAACCAATTCAGAATTCATCGCGATGGTTGCTGACAAGCTGAGATTGGAGCATAAAGCTTCGTA
A

Domains

Predicted by InterproScan.

Sporulation initiation factor Spo0A C terminal (Spo0A_C)

(156-259)

Response regulator receiver domain (Response_reg)

(6-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C7K5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  spo0A Bacillus subtilis subsp. subtilis str. 168

96.629

100

0.97