Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   QPR37_RS10465 Genome accession   NZ_CP126631
Coordinates   2116584..2118593 (-) Length   669 a.a.
NCBI ID   WP_259378596.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 33-40     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2111584..2123593
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QPR37_RS10450 (QPR37_10450) glpK 2113120..2114616 (-) 1497 WP_000417379.1 glycerol kinase GlpK -
  QPR37_RS10455 (QPR37_10455) - 2114745..2115563 (-) 819 WP_285146933.1 MIP/aquaporin family protein -
  QPR37_RS10460 (QPR37_10460) - 2116036..2116578 (-) 543 WP_001077635.1 glycerol-3-phosphate responsive antiterminator -
  QPR37_RS10465 (QPR37_10465) hexB 2116584..2118593 (-) 2010 WP_259378596.1 DNA mismatch repair endonuclease MutL Machinery gene
  QPR37_RS10470 (QPR37_10470) hexA 2118606..2121224 (-) 2619 WP_063651255.1 DNA mismatch repair protein MutS Machinery gene
  QPR37_RS10475 (QPR37_10475) thiW 2121527..2122018 (-) 492 WP_000842277.1 energy coupling factor transporter S component ThiW -
  QPR37_RS10480 (QPR37_10480) - 2122045..2122410 (-) 366 WP_000282386.1 RicAFT regulatory complex protein RicA family protein -

Sequence

Protein


Download         Length: 669 a.a.        Molecular weight: 76868.20 Da        Isoelectric Point: 5.2023

>NTDB_id=768013 QPR37_RS10465 WP_259378596.1 2116584..2118593(-) (hexB) [Staphylococcus aureus strain 33-40]
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSK
LDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPE
HSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSK
IQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQNTENNQEKTFSSEESNSKPFMAENQNDEIVIKEDSYNPFV
TKTSESLIADDESSGYNNTREKDKDYFKKQQEILQEMDQTFDSNDDTSVQNYENKASDDYYDVNDIKGTKSKDPKRRIPY
MEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKKELQQVGIM
LEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKLDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREA
EDPFTCPHGRPIIINFSKYELEKIFKRVM

Nucleotide


Download         Length: 2010 bp        

>NTDB_id=768013 QPR37_RS10465 WP_259378596.1 2116584..2118593(-) (hexB) [Staphylococcus aureus strain 33-40]
ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTAGTTGAAAGACCGAGTTCTGT
TGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCTACAGAAATAAGCATTGAAGTAGAGGAATCTGGCGTCCAAT
CTATTCGCGTAGTCGATAATGGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGACATGCGACTAGTAAA
TTAGATCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTAGCCAGTATTTCATCAGTTGC
TAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGAAATGAAATATATGTAGAAAATGGTGAAATATTAAATCATA
AGCCTGCAAAAGCGAAAAAAGGAACAGATATACTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATA
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAACAGAATGGCAATGAGCCATCCGGACATTCGAATAGC
GCTCATTTCAGATGGTAAAACAATGTTAAGTACAAATGGTTCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGA
TGAAAGTTGCACGAGATTTAGTGCATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAACTTTATGTTAAATAAAGCGAT
TTTAGAAGGCTATCATACACTCTTAACAATAGGTAGGTTCCCGATTTGTTATATTAATATTGAAATGGATCCAATCTTAG
TAGACGTAAATGTTCATCCAACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATACCAATTGATTGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCGAAAAAAAATAAAGTGTTACA
TTCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAAAACACAGAGAATAACCAAGAGAAGACGTTTTCATCTGAAG
AAAGTAACAGTAAGCCATTTATGGCAGAAAATCAAAACGATGAGATAGTTATAAAAGAAGATTCGTATAATCCATTCGTA
ACGAAAACGTCTGAAAGTTTAATAGCTGATGATGAATCTTCCGGTTATAATAATACACGTGAAAAAGATAAAGACTACTT
CAAAAAACAACAAGAAATTTTACAAGAAATGGATCAAACATTTGATTCAAATGACGATACATCTGTGCAAAATTATGAGA
ATAAAGCGTCCGATGATTATTATGATGTAAACGATATTAAAGGAACAAAAAGTAAAGACCCTAAACGAAGAATTCCATAT
ATGGAAATTGTTGGCCAAGTACATGGAACGTATATTATTGCTCAAAATGAATTTGGCATGTACATGATTGACCAGCATGC
AGCTCAAGAAAGAATAAAATATGAATATTTTCGAGATAAAATAGGTGAAGTTACCAATGAAGTACAAGATTTATTAATCC
CGTTAACATTTCATTTTTCAAAAGATGAACAACTAGTCATTGATCAATATAAAAAGGAGCTTCAACAAGTAGGTATCATG
TTAGAACATTTTGGTGGTCATGATTATATTGTAAGTAGCTATCCAGTTTGGTTCCCTAAAGATGAAGTAGAAGAAATTAT
TAAAGATATGATTGAGCTAATTTTGGAAGAGAAAAAATTAGATATCAAAAAATTACGTGAAGATGTAGCAATCATGATGT
CATGTAAAAAATCTATTAAAGCGAATCATTATTTACAAAAACATGAAATGTCTGATTTAATTGATCAATTAAGAGAAGCG
GAAGATCCATTTACATGTCCACATGGTCGTCCAATTATCATTAATTTTTCAAAATACGAATTAGAAAAAATATTTAAGCG
TGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-325)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

MutL C terminal dimerisation domain (MutL_C)

(483-625)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

40.68

100

0.411