Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   O6R09_RS06735 Genome accession   NZ_CP114883
Coordinates   1321146..1321856 (-) Length   236 a.a.
NCBI ID   WP_269725551.1    Uniprot ID   -
Organism   Streptococcus alactolyticus strain LGM     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1316146..1326856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS06720 (O6R09_06720) rnc 1318109..1318795 (-) 687 WP_269725549.1 ribonuclease III -
  O6R09_RS06725 (O6R09_06725) vicX 1319000..1319809 (-) 810 WP_269725550.1 MBL fold metallo-hydrolase Regulator
  O6R09_RS06730 (O6R09_06730) vicK 1319810..1321153 (-) 1344 WP_154455018.1 cell wall metabolism sensor histidine kinase VicK Regulator
  O6R09_RS06735 (O6R09_06735) vicR 1321146..1321856 (-) 711 WP_269725551.1 response regulator YycF Regulator
  O6R09_RS06740 (O6R09_06740) - 1322147..1322911 (+) 765 WP_167829297.1 amino acid ABC transporter ATP-binding protein -
  O6R09_RS06745 (O6R09_06745) - 1322926..1323738 (+) 813 WP_269725552.1 transporter substrate-binding domain-containing protein -
  O6R09_RS06750 (O6R09_06750) - 1323753..1324451 (+) 699 WP_154455015.1 amino acid ABC transporter permease -
  O6R09_RS06755 (O6R09_06755) - 1324463..1325110 (+) 648 WP_154455014.1 amino acid ABC transporter permease -
  O6R09_RS06760 (O6R09_06760) - 1325153..1325761 (-) 609 WP_269725873.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27162.05 Da        Isoelectric Point: 4.7716

>NTDB_id=767343 O6R09_RS06735 WP_269725551.1 1321146..1321856(-) (vicR) [Streptococcus alactolyticus strain LGM]
MKKILIIDDEKPISDIIKFNLNKEGYETITAFDGREALKKFEEESPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASTTGSEIVIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=767343 O6R09_RS06735 WP_269725551.1 1321146..1321856(-) (vicR) [Streptococcus alactolyticus strain LGM]
ATGAAAAAAATTCTTATTATTGATGATGAAAAACCGATTTCGGATATTATTAAATTTAATTTGAACAAGGAAGGTTATGA
AACCATCACGGCTTTTGATGGTCGTGAAGCCTTGAAGAAATTTGAGGAAGAATCGCCTGATTTGATTATTTTGGACTTGA
TGTTGCCAGAATTAGACGGGCTTGAAGTGGCTAAGGAAGTTCGTAAAACGAGCCACATTCCGATTATCATGCTATCGGCT
AAAGATAGTGAGTTTGATAAGGTTATTGGTTTGGAAATTGGGGCCGATGATTATGTGACTAAACCATTTTCAAATCGTGA
GTTGTTGGCGCGTGTGAAGGCTCACTTGCGACGCACGGAAAACATTGAAAGTGCCGTGGCTGAGGAAAATGCCTCAACAA
CTGGTTCTGAAATTGTGATTGGGGATTTGAAGATTTTGCCAGATGCTTTTGTTGCTCAAAAACGTGGGGAAGATATCGAA
TTGACCCACCGTGAATTTGAATTATTGCATCATTTGGCAACCCACATGGGACAAGTGATGACGCGTGAATATTTGTTGGA
AACGGTTTGGGGCTATGATTATTTCGGCGATGTTCGTACTGTTGACGTGACGATTCGTCGCTTGCGTGAAAAAATCGAAG
ACACGCCTAGCCGACCTGAATACATTTTGACCCGACGTGGTGTTGGTTATTACATGAAATCTTATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

76.923

99.153

0.763
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.552

98.305

0.458
  covR Streptococcus salivarius strain HSISS4

46.121

98.305

0.453
  scnR Streptococcus mutans UA159

39.331

100

0.398