Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   O6R09_RS06730 Genome accession   NZ_CP114883
Coordinates   1319810..1321153 (-) Length   447 a.a.
NCBI ID   WP_154455018.1    Uniprot ID   -
Organism   Streptococcus alactolyticus strain LGM     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1314810..1326153
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS06720 (O6R09_06720) rnc 1318109..1318795 (-) 687 WP_269725549.1 ribonuclease III -
  O6R09_RS06725 (O6R09_06725) vicX 1319000..1319809 (-) 810 WP_269725550.1 MBL fold metallo-hydrolase Regulator
  O6R09_RS06730 (O6R09_06730) vicK 1319810..1321153 (-) 1344 WP_154455018.1 cell wall metabolism sensor histidine kinase VicK Regulator
  O6R09_RS06735 (O6R09_06735) vicR 1321146..1321856 (-) 711 WP_269725551.1 response regulator YycF Regulator
  O6R09_RS06740 (O6R09_06740) - 1322147..1322911 (+) 765 WP_167829297.1 amino acid ABC transporter ATP-binding protein -
  O6R09_RS06745 (O6R09_06745) - 1322926..1323738 (+) 813 WP_269725552.1 transporter substrate-binding domain-containing protein -
  O6R09_RS06750 (O6R09_06750) - 1323753..1324451 (+) 699 WP_154455015.1 amino acid ABC transporter permease -
  O6R09_RS06755 (O6R09_06755) - 1324463..1325110 (+) 648 WP_154455014.1 amino acid ABC transporter permease -
  O6R09_RS06760 (O6R09_06760) - 1325153..1325761 (-) 609 WP_269725873.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 51263.49 Da        Isoelectric Point: 5.0869

>NTDB_id=767342 O6R09_RS06730 WP_154455018.1 1319810..1321153(-) (vicK) [Streptococcus alactolyticus strain LGM]
MNKVMLDYFEQTLLFLLAFVAVYFVYLAIRDYRTSLNIRRLSGKVRELITGQYSEDIVIKKDRDLAELAAQLNDLSTVFR
LAQENLAQEKNRLASILSYMTDGVLATDRAGNITMINQTAQQQLNLERVEALKLNIIDILGSDSHYTYHDLVSKTPEIVL
NRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALKEDI
APSFIKVSLDETNRMIRMISDLLNLSRIDNQTVRLEVEVTNFTAFMTSILNRFDQIKNQDTISGKYYEIVRDYPIKPIWL
EIDPDKMTQVLDNILNNAIKYSPDGGKITVKMRTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSGLGL
AIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSEVYDEWEDNEE

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=767342 O6R09_RS06730 WP_154455018.1 1319810..1321153(-) (vicK) [Streptococcus alactolyticus strain LGM]
ATGAATAAGGTAATGTTAGATTATTTTGAGCAAACGCTCCTCTTCCTTTTAGCTTTTGTAGCGGTTTATTTTGTGTATTT
GGCGATTCGTGATTACCGCACGTCTCTTAATATCAGGCGTTTAAGCGGTAAGGTGCGAGAGCTGATTACAGGACAATATT
CCGAAGACATTGTTATCAAAAAAGATAGAGATTTAGCAGAATTAGCAGCGCAATTAAATGATTTGTCAACCGTCTTTCGC
TTAGCCCAAGAAAATTTAGCCCAAGAAAAAAATCGTTTAGCCAGCATCTTGTCTTACATGACCGATGGGGTGCTTGCTAC
GGACCGTGCGGGCAATATCACCATGATTAACCAAACGGCGCAGCAGCAGCTGAATTTGGAGCGCGTGGAGGCTTTGAAAC
TTAATATCATTGATATTTTAGGGTCGGACAGTCATTACACTTATCATGATTTGGTGTCAAAGACGCCTGAGATTGTTTTA
AACCGTCGGGACGAAACGGGTGAATTTATCACCTTGCGTATTCGATTTGCCTTAAATCGCCGTGATAGTGGCTTTATTTC
AGGGCTTATTGCCGTTTTGCACGACACAACTGAGCAGGAAAAAGAAGACAGGGAGCGTCGCCTCTTTGTTTCCAATGTCA
GTCACGAGTTGCGGACGCCCTTGACCTCTGTCAAATCGTATCTGGAAGCTTTGGACGAGGGAGCGCTGAAAGAAGATATC
GCCCCTAGCTTTATCAAGGTGTCTTTGGATGAGACTAATCGCATGATTCGCATGATTTCGGACTTGCTCAACCTATCGCG
GATTGATAATCAGACGGTTCGTCTGGAAGTAGAAGTGACCAATTTTACAGCTTTTATGACCTCGATTTTGAACCGTTTTG
ACCAAATCAAAAACCAAGATACCATTAGTGGCAAGTATTACGAGATTGTGCGTGATTACCCTATCAAGCCTATTTGGCTG
GAAATTGACCCAGATAAAATGACGCAAGTCTTGGATAACATTTTAAACAATGCTATCAAGTATTCGCCAGATGGTGGCAA
AATTACGGTGAAAATGCGGACGACAGAAACCCAGTTAATCATTTCCATTTCTGATGAGGGGCTTGGTATTCCGAAAAAAG
ATTTGCCGCTTATCTTTGATCGTTTCTACCGTGTGGATAAGGCAAGAAGCCGTGCCCAAGGTGGTTCAGGGCTTGGTTTA
GCTATTGCCAAGGAAATTGTCAAACAACACAAGGGCTTTATTTGGGCACAAAGTACATATGGAAAGGGCTCAACCTTTAC
GATTGTACTTCCATATGAAAAAGATTCTGAAGTTTATGATGAATGGGAGGACAATGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(323-433)

His Kinase A (phospho-acceptor) domain (HisKA)

(206-270)

PAS fold (PAS)

(92-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

71.882

98.658

0.709
  micB Streptococcus pneumoniae Cp1015

64.091

98.434

0.631