Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   OXA89_RS07450 Genome accession   NZ_CP113434
Coordinates   1644994..1646214 (+) Length   406 a.a.
NCBI ID   WP_027219448.1    Uniprot ID   -
Organism   Legionella pneumophila strain PATHC027     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1639994..1651214
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OXA89_RS07430 (OXA89_07430) - 1641129..1641698 (-) 570 WP_011213801.1 hypoxanthine-guanine phosphoribosyltransferase -
  OXA89_RS07435 (OXA89_07435) - 1641741..1642067 (-) 327 WP_027219451.1 DUF1820 family protein -
  OXA89_RS07440 (OXA89_07440) - 1642250..1642993 (-) 744 WP_027219450.1 methyltransferase domain-containing protein -
  OXA89_RS07445 (OXA89_07445) pilB 1643264..1644988 (+) 1725 WP_027219449.1 type IV-A pilus assembly ATPase PilB Machinery gene
  OXA89_RS07450 (OXA89_07450) pilC 1644994..1646214 (+) 1221 WP_027219448.1 type II secretion system F family protein Machinery gene
  OXA89_RS07455 (OXA89_07455) - 1646260..1647123 (+) 864 WP_027219447.1 prepilin peptidase -
  OXA89_RS07460 (OXA89_07460) - 1647137..1648342 (-) 1206 WP_027223897.1 cyclic nucleotide-binding domain-containing protein -
  OXA89_RS07465 (OXA89_07465) - 1648450..1649043 (-) 594 WP_011946528.1 hypothetical protein -
  OXA89_RS07470 (OXA89_07470) - 1649059..1649514 (-) 456 WP_011946529.1 hypothetical protein -
  OXA89_RS07475 (OXA89_07475) - 1649648..1650463 (+) 816 WP_010947257.1 pyruvate, water dikinase regulatory protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44677.88 Da        Isoelectric Point: 9.5994

>NTDB_id=762028 OXA89_RS07450 WP_027219448.1 1644994..1646214(+) (pilC) [Legionella pneumophila strain PATHC027]
MDKNSPPLLTFHYQGINKAGQKMEGDIQAKSLAIAKADLRKQGIVTNKVVKKRKPLFDRKNKKITQADITVFSRQLATMI
ESGIPLVQAFDIVAKGQSNKRLKDLIETIKHDIETGLTLAESLIKHPLYFNELFCNLVDAGEKSGSLDIMLDKVATYKEK
IEIIKKKIKKALTYPIAVMVVALLVTAGLLIYVVPQFESLFKGFGADLPAMTRAVITMSEFMQAYWYIIFGTLGGIVYGF
FYAKNHSLEFAQTIDRVMLKFPVIGPILEKAAIARFARTLSITFAAGLPLVEALKSVAGATGNIIYAKATDKIREEVATG
QQMFVAMENTHLFPNMVIQMVAIGEESGALEKMLSKVADFYEEEVNNAVDALSSLLEPIIMSILGILVGGLVVAMYLPIF
KLGSAV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=762028 OXA89_RS07450 WP_027219448.1 1644994..1646214(+) (pilC) [Legionella pneumophila strain PATHC027]
ATGGATAAAAATAGCCCACCCCTATTAACCTTTCATTATCAAGGCATCAATAAAGCTGGTCAAAAAATGGAAGGTGATAT
TCAAGCCAAAAGCTTGGCAATAGCTAAAGCTGATTTACGTAAGCAGGGAATTGTCACCAATAAAGTAGTTAAAAAAAGAA
AACCTTTGTTTGATAGAAAAAACAAAAAAATCACACAAGCGGATATTACCGTGTTCAGCCGCCAATTAGCGACGATGATA
GAGTCAGGGATACCATTAGTGCAAGCGTTTGATATTGTTGCCAAAGGACAAAGCAATAAAAGACTTAAAGACTTAATAGA
AACAATTAAGCACGATATCGAAACGGGGCTAACGCTGGCAGAATCCTTAATTAAACATCCACTCTATTTTAATGAATTAT
TTTGTAATCTTGTCGATGCAGGTGAAAAATCAGGCTCATTAGATATCATGCTTGATAAGGTTGCAACGTATAAAGAAAAA
ATTGAAATCATAAAAAAGAAAATAAAGAAAGCTCTAACTTACCCAATTGCTGTTATGGTTGTCGCGCTTTTGGTTACTGC
GGGATTATTAATCTATGTGGTTCCACAATTTGAATCGCTGTTTAAAGGATTTGGAGCTGATTTGCCAGCGATGACTAGAG
CTGTAATTACTATGTCTGAATTTATGCAGGCTTATTGGTATATTATTTTTGGAACTTTGGGTGGGATTGTATATGGTTTT
TTTTACGCTAAAAATCATTCTTTGGAGTTCGCACAAACTATTGACAGAGTGATGCTAAAGTTTCCTGTAATTGGCCCTAT
CTTAGAGAAAGCAGCAATTGCTCGATTCGCAAGGACATTATCGATTACTTTTGCTGCTGGATTACCCCTGGTTGAAGCTT
TGAAATCTGTAGCTGGAGCGACTGGAAATATTATTTATGCCAAGGCGACTGATAAAATCAGAGAAGAAGTTGCCACAGGA
CAGCAAATGTTTGTTGCTATGGAAAACACACATTTATTTCCAAATATGGTAATTCAAATGGTAGCAATTGGTGAGGAATC
AGGTGCCCTTGAGAAAATGTTAAGCAAAGTAGCTGATTTTTATGAGGAAGAAGTAAATAATGCTGTAGATGCTCTGAGTA
GTTTATTGGAGCCGATAATTATGTCAATATTGGGTATACTGGTTGGGGGATTGGTGGTGGCTATGTATTTACCTATTTTC
AAACTGGGTTCCGCTGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

98.522

100

0.985
  pilC Pseudomonas stutzeri DSM 10701

54.208

99.507

0.539
  pilC Acinetobacter baumannii D1279779

53.333

99.754

0.532
  pilC Acinetobacter baylyi ADP1

52.84

99.754

0.527
  pilG Neisseria gonorrhoeae MS11

44.836

97.783

0.438
  pilG Neisseria meningitidis 44/76-A

44.836

97.783

0.438
  pilC Vibrio cholerae strain A1552

42

98.522

0.414
  pilC Vibrio campbellii strain DS40M4

38.67

100

0.387