Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   OTB22_RS09815 Genome accession   NZ_CP113267
Coordinates   1909818..1910834 (-) Length   338 a.a.
NCBI ID   WP_075218762.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1904818..1915834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTB22_RS09770 (OTB22_09775) - 1904895..1905026 (-) 132 WP_000768904.1 hypothetical protein -
  OTB22_RS09775 (OTB22_09780) - 1905027..1906217 (-) 1191 WP_050245357.1 acetate kinase -
  OTB22_RS09780 (OTB22_09785) comYH 1906268..1907221 (-) 954 WP_050233486.1 class I SAM-dependent methyltransferase Machinery gene
  OTB22_RS09785 (OTB22_09790) - 1907282..1907876 (-) 595 Protein_1908 class I SAM-dependent methyltransferase -
  OTB22_RS09790 (OTB22_09795) comGG/cglG 1908013..1908426 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  OTB22_RS09795 (OTB22_09800) comGF/cglF 1908404..1908865 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  OTB22_RS09800 (OTB22_09805) comGE/cglE 1908828..1909130 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  OTB22_RS09805 (OTB22_09810) comGD/cglD 1909093..1909497 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  OTB22_RS09810 (OTB22_09815) comGC/cglC 1909490..1909816 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  OTB22_RS09815 (OTB22_09820) comGB/cglB 1909818..1910834 (-) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  OTB22_RS09820 (OTB22_09825) comGA/cglA/cilD 1910782..1911723 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  OTB22_RS09825 (OTB22_09830) - 1911799..1912164 (-) 366 WP_000286415.1 DUF1033 family protein -
  OTB22_RS09830 (OTB22_09835) - 1912315..1913373 (-) 1059 WP_000649470.1 zinc-dependent alcohol dehydrogenase family protein -
  OTB22_RS09835 (OTB22_09840) - 1913628..1914904 (+) 1277 Protein_1918 ISL3 family transposase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38478.51 Da        Isoelectric Point: 9.6073

>NTDB_id=761516 OTB22_RS09815 WP_075218762.1 1909818..1910834(-) (comGB/cglB) [Streptococcus pneumoniae strain BC2]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVIQMRAGLSQGKSFSEMMESLGFSSTI
ITQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=761516 OTB22_RS09815 WP_075218762.1 1909818..1910834(-) (comGB/cglB) [Streptococcus pneumoniae strain BC2]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGATCCAGATGCGTGCGGGCTTGTCTCAAGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATTTTCAAGCACCATT
ATCACTCAGTTATCCCTAGCTGAAGTTCATGGAAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCTAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCAAATTATCGGTAATCTGCCCCAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae D39

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae R6

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae TIGR4

98.225

100

0.982
  comGB/cglB Streptococcus mitis SK321

94.97

100

0.95
  comGB/cglB Streptococcus mitis NCTC 12261

94.675

100

0.947
  comYB Streptococcus gordonii str. Challis substr. CH1

71.131

99.408

0.707
  comYB Streptococcus mutans UA140

57.862

94.083

0.544
  comYB Streptococcus mutans UA159

57.862

94.083

0.544
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503