Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   OTB22_RS09800 Genome accession   NZ_CP113267
Coordinates   1908828..1909130 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1903828..1914130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTB22_RS09765 (OTB22_09770) rnpA 1904507..1904878 (-) 372 WP_000739246.1 ribonuclease P protein component -
  OTB22_RS09770 (OTB22_09775) - 1904895..1905026 (-) 132 WP_000768904.1 hypothetical protein -
  OTB22_RS09775 (OTB22_09780) - 1905027..1906217 (-) 1191 WP_050245357.1 acetate kinase -
  OTB22_RS09780 (OTB22_09785) comYH 1906268..1907221 (-) 954 WP_050233486.1 class I SAM-dependent methyltransferase Machinery gene
  OTB22_RS09785 (OTB22_09790) - 1907282..1907876 (-) 595 Protein_1908 class I SAM-dependent methyltransferase -
  OTB22_RS09790 (OTB22_09795) comGG/cglG 1908013..1908426 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  OTB22_RS09795 (OTB22_09800) comGF/cglF 1908404..1908865 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  OTB22_RS09800 (OTB22_09805) comGE/cglE 1908828..1909130 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  OTB22_RS09805 (OTB22_09810) comGD/cglD 1909093..1909497 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  OTB22_RS09810 (OTB22_09815) comGC/cglC 1909490..1909816 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  OTB22_RS09815 (OTB22_09820) comGB/cglB 1909818..1910834 (-) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  OTB22_RS09820 (OTB22_09825) comGA/cglA/cilD 1910782..1911723 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  OTB22_RS09825 (OTB22_09830) - 1911799..1912164 (-) 366 WP_000286415.1 DUF1033 family protein -
  OTB22_RS09830 (OTB22_09835) - 1912315..1913373 (-) 1059 WP_000649470.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=761513 OTB22_RS09800 WP_000413382.1 1908828..1909130(-) (comGE/cglE) [Streptococcus pneumoniae strain BC2]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=761513 OTB22_RS09800 WP_000413382.1 1908828..1909130(-) (comGE/cglE) [Streptococcus pneumoniae strain BC2]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4