Detailed information NTG0761512

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: OTB22_RS09795
• Genome accession: NZ_CP113267
• Coordinates: 1908404..1908865 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BC2
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1903404..1913865

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OTB22_RS09760 (OTB22_09765)	-	1903708..1904532 (-)	825	WP_001832473.1	membrane protein insertase YidC	-
OTB22_RS09765 (OTB22_09770)	rnpA	1904507..1904878 (-)	372	WP_000739246.1	ribonuclease P protein component	-
OTB22_RS09770 (OTB22_09775)	-	1904895..1905026 (-)	132	WP_000768904.1	hypothetical protein	-
OTB22_RS09775 (OTB22_09780)	-	1905027..1906217 (-)	1191	WP_050245357.1	acetate kinase	-
OTB22_RS09780 (OTB22_09785)	comYH	1906268..1907221 (-)	954	WP_050233486.1	class I SAM-dependent methyltransferase	Machinery gene
OTB22_RS09785 (OTB22_09790)	-	1907282..1907876 (-)	595	Protein_1908	class I SAM-dependent methyltransferase	-
OTB22_RS09790 (OTB22_09795)	comGG/cglG	1908013..1908426 (-)	414	WP_000265620.1	competence type IV pilus minor pilin ComGG	Machinery gene
OTB22_RS09795 (OTB22_09800)	comGF/cglF	1908404..1908865 (-)	462	WP_000250540.1	competence type IV pilus minor pilin ComGF	Machinery gene
OTB22_RS09800 (OTB22_09805)	comGE/cglE	1908828..1909130 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
OTB22_RS09805 (OTB22_09810)	comGD/cglD	1909093..1909497 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
OTB22_RS09810 (OTB22_09815)	comGC/cglC	1909490..1909816 (-)	327	WP_000738630.1	comG operon protein ComGC	Machinery gene
OTB22_RS09815 (OTB22_09820)	comGB/cglB	1909818..1910834 (-)	1017	WP_075218762.1	competence type IV pilus assembly protein ComGB	Machinery gene
OTB22_RS09820 (OTB22_09825)	comGA/cglA/cilD	1910782..1911723 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
OTB22_RS09825 (OTB22_09830)	-	1911799..1912164 (-)	366	WP_000286415.1	DUF1033 family protein	-
OTB22_RS09830 (OTB22_09835)	-	1912315..1913373 (-)	1059	WP_000649470.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17850.40 Da
• Isoelectric Point: 8.0016

>NTDB_id=761512 OTB22_RS09795 WP_000250540.1 1908404..1908865(-) (comGF/cglF) [Streptococcus pneumoniae strain BC2]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=761512 OTB22_RS09795 WP_000250540.1 1908404..1908865(-) (comGF/cglF) [Streptococcus pneumoniae strain BC2]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae D39	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae R6	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae TIGR4	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	93.464	100	0.935
comGF/cglF	Streptococcus mitis NCTC 12261	92.157	100	0.922