Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Regulator
Locus tag   UKS_RS09660 Genome accession   NZ_AP021887
Coordinates   1940468..1940599 (-) Length   43 a.a.
NCBI ID   WP_156012998.1    Uniprot ID   A0A6H3SN42
Organism   Streptococcus sp. 116-D4     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1935468..1945599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UKS_RS09635 (UKS_18700) - 1937597..1938139 (+) 543 WP_156012995.1 TetR-like C-terminal domain-containing protein -
  UKS_RS09650 (UKS_18710) comE 1938382..1939134 (-) 753 WP_000866062.1 competence system response regulator transcription factor ComE Regulator
  UKS_RS09655 (UKS_18720) comD/comD1 1939131..1940456 (-) 1326 WP_156012996.1 competence system sensor histidine kinase ComD Regulator
  UKS_RS09660 (UKS_18730) comC 1940468..1940599 (-) 132 WP_156012998.1 competence-stimulating peptide ComC Regulator
  UKS_RS09670 (UKS_18740) rlmH 1940882..1941361 (-) 480 WP_049496558.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  UKS_RS09675 (UKS_18750) htrA 1941549..1942730 (+) 1182 WP_156013000.1 S1C family serine protease Regulator
  UKS_RS09680 (UKS_18760) spo0J 1942788..1943546 (+) 759 WP_156013002.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 43 a.a.        Molecular weight: 5204.16 Da        Isoelectric Point: 11.1475

>NTDB_id=75394 UKS_RS09660 WP_156012998.1 1940468..1940599(-) (comC) [Streptococcus sp. 116-D4]
MKNTVKLEKFVALQEKDLQNIKGGEMRKMNEKSFNIFSLFRRR

Nucleotide


Download         Length: 132 bp        

>NTDB_id=75394 UKS_RS09660 WP_156012998.1 1940468..1940599(-) (comC) [Streptococcus sp. 116-D4]
ATGAAAAACACGGTTAAATTGGAAAAGTTTGTAGCCTTGCAGGAAAAAGATTTGCAAAATATTAAAGGTGGGGAGATGAG
GAAAATGAATGAAAAGTCCTTTAATATTTTTAGTTTATTTAGAAGAAGATAA

Domains

Predicted by InterproScan.

COMC family (ComC)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6H3SN42

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus mitis NCTC 12261

64.865

86.047

0.558
  comC/comC2 Streptococcus pneumoniae TIGR4

88.889

62.791

0.558
  comC/comC1 Streptococcus pneumoniae R6

88.889

62.791

0.558
  comC/comC1 Streptococcus pneumoniae G54

88.889

62.791

0.558
  comC/comC1 Streptococcus pneumoniae D39

88.889

62.791

0.558
  comC/comC1 Streptococcus pneumoniae Rx1

88.889

62.791

0.558
  comC/comC2 Streptococcus pneumoniae A66

88.889

62.791

0.558
  comC Streptococcus mitis SK321

81.481

62.791

0.512

Multiple sequence alignment