Detailed information
Bioinformatically predicted
Overview
| Name | clpP | Type | Regulator |
| Locus tag | NOV96_RS03545 | Genome accession | NZ_CP110141 |
| Coordinates | 700375..700965 (+) | Length | 196 a.a. |
| NCBI ID | WP_002937303.1 | Uniprot ID | A0A0K2E545 |
| Organism | Streptococcus suis strain WUSS030 | ||
| Function | degradation of ComX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 700375..774188 | 700375..700965 | within | 0 |
Gene organization within MGE regions
Location: 700375..774188
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NOV96_RS03545 (NOV96_03545) | clpP | 700375..700965 (+) | 591 | WP_002937303.1 | ATP-dependent Clp protease proteolytic subunit | Regulator |
| NOV96_RS03550 (NOV96_03550) | - | 701092..701364 (+) | 273 | WP_002937299.1 | YlbG family protein | - |
| NOV96_RS03555 (NOV96_03555) | - | 701495..702664 (+) | 1170 | WP_002937297.1 | ABC transporter substrate-binding protein | - |
| NOV96_RS03560 (NOV96_03560) | - | 702870..703757 (+) | 888 | WP_002937296.1 | branched-chain amino acid ABC transporter permease | - |
| NOV96_RS03565 (NOV96_03565) | - | 703760..704707 (+) | 948 | WP_002937293.1 | branched-chain amino acid ABC transporter permease | - |
| NOV96_RS03570 (NOV96_03570) | - | 704707..705471 (+) | 765 | WP_002937291.1 | ABC transporter ATP-binding protein | - |
| NOV96_RS03575 (NOV96_03575) | - | 705471..706181 (+) | 711 | WP_002937288.1 | ABC transporter ATP-binding protein | - |
| NOV96_RS03580 (NOV96_03580) | - | 706552..707307 (+) | 756 | WP_002937287.1 | epoxyqueuosine reductase QueH | - |
| NOV96_RS03585 (NOV96_03585) | - | 707415..708005 (+) | 591 | WP_013730461.1 | hypothetical protein | - |
| NOV96_RS03590 (NOV96_03590) | holA | 708155..709186 (+) | 1032 | WP_013730460.1 | DNA polymerase III subunit delta | - |
| NOV96_RS03595 (NOV96_03595) | sodA | 709299..709904 (+) | 606 | WP_013730459.1 | superoxide dismutase SodA | - |
| NOV96_RS03600 (NOV96_03600) | - | 710166..712190 (+) | 2025 | WP_022540664.1 | bifunctional UDP-sugar hydrolase/5'-nucleotidase | - |
| NOV96_RS03610 (NOV96_03610) | - | 712497..713591 (-) | 1095 | WP_112493931.1 | tyrosine-type recombinase/integrase | - |
| NOV96_RS03615 (NOV96_03615) | - | 713720..714154 (-) | 435 | WP_112493932.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| NOV96_RS03620 (NOV96_03620) | - | 714511..715281 (-) | 771 | WP_074390660.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| NOV96_RS03625 (NOV96_03625) | - | 715291..716034 (-) | 744 | WP_105204043.1 | XRE family transcriptional regulator | - |
| NOV96_RS03630 (NOV96_03630) | - | 716528..716734 (+) | 207 | WP_014636684.1 | helix-turn-helix transcriptional regulator | - |
| NOV96_RS03635 (NOV96_03635) | - | 716775..717101 (+) | 327 | WP_074390658.1 | hypothetical protein | - |
| NOV96_RS03640 (NOV96_03640) | - | 717456..717731 (+) | 276 | WP_024377134.1 | hypothetical protein | - |
| NOV96_RS03645 (NOV96_03645) | - | 717721..717867 (+) | 147 | WP_161948697.1 | hypothetical protein | - |
| NOV96_RS03650 (NOV96_03650) | - | 717877..718158 (+) | 282 | WP_105204045.1 | hypothetical protein | - |
| NOV96_RS03655 (NOV96_03655) | - | 718176..718502 (+) | 327 | WP_024390775.1 | hypothetical protein | - |
| NOV96_RS03660 (NOV96_03660) | - | 718820..719131 (+) | 312 | WP_074390655.1 | hypothetical protein | - |
| NOV96_RS03665 (NOV96_03665) | - | 719131..720288 (+) | 1158 | WP_105204047.1 | DUF2800 domain-containing protein | - |
| NOV96_RS03670 (NOV96_03670) | - | 720300..720860 (+) | 561 | WP_024390779.1 | DUF2815 family protein | - |
| NOV96_RS03675 (NOV96_03675) | - | 720873..722795 (+) | 1923 | WP_105204049.1 | DNA polymerase | - |
| NOV96_RS03680 (NOV96_03680) | - | 722799..725177 (+) | 2379 | WP_105204051.1 | DNA primase family protein | - |
| NOV96_RS03685 (NOV96_03685) | - | 725545..725820 (+) | 276 | WP_087013660.1 | VRR-NUC domain-containing protein | - |
| NOV96_RS03690 (NOV96_03690) | - | 725807..727129 (+) | 1323 | WP_238709805.1 | SNF2-related protein | - |
| NOV96_RS03695 (NOV96_03695) | - | 727131..727286 (+) | 156 | WP_162841286.1 | hypothetical protein | - |
| NOV96_RS03700 (NOV96_03700) | - | 727283..727591 (+) | 309 | WP_013730180.1 | DUF1372 family protein | - |
| NOV96_RS03705 (NOV96_03705) | - | 727593..727808 (+) | 216 | WP_013730181.1 | hypothetical protein | - |
| NOV96_RS03710 (NOV96_03710) | - | 727997..728314 (+) | 318 | WP_044752290.1 | hypothetical protein | - |
| NOV96_RS03715 (NOV96_03715) | - | 728389..728802 (+) | 414 | WP_044752555.1 | DUF722 domain-containing protein | - |
| NOV96_RS03730 (NOV96_03730) | - | 729372..729815 (+) | 444 | WP_230334509.1 | terminase small subunit | - |
| NOV96_RS03735 (NOV96_03735) | - | 729802..731100 (+) | 1299 | WP_105204197.1 | PBSX family phage terminase large subunit | - |
| NOV96_RS03740 (NOV96_03740) | - | 731111..732598 (+) | 1488 | WP_044684402.1 | phage portal protein | - |
| NOV96_RS03745 (NOV96_03745) | - | 732591..734240 (+) | 1650 | WP_105204199.1 | phage minor capsid protein | - |
| NOV96_RS03750 (NOV96_03750) | - | 734227..734502 (+) | 276 | WP_044684405.1 | hypothetical protein | - |
| NOV96_RS03755 (NOV96_03755) | - | 734555..734875 (+) | 321 | WP_044752553.1 | hypothetical protein | - |
| NOV96_RS03760 (NOV96_03760) | - | 734872..735105 (+) | 234 | WP_044684408.1 | hypothetical protein | - |
| NOV96_RS03765 (NOV96_03765) | - | 735116..735367 (+) | 252 | WP_024390611.1 | DUF6275 family protein | - |
| NOV96_RS03770 (NOV96_03770) | - | 735529..736131 (+) | 603 | WP_044684410.1 | hypothetical protein | - |
| NOV96_RS03775 (NOV96_03775) | - | 736133..736945 (+) | 813 | WP_024390609.1 | N4-gp56 family major capsid protein | - |
| NOV96_RS03780 (NOV96_03780) | - | 736961..737152 (+) | 192 | WP_029188597.1 | hypothetical protein | - |
| NOV96_RS03785 (NOV96_03785) | - | 737176..737568 (+) | 393 | WP_044684415.1 | hypothetical protein | - |
| NOV96_RS03790 (NOV96_03790) | - | 737570..737911 (+) | 342 | WP_044667213.1 | putative minor capsid protein | - |
| NOV96_RS03795 (NOV96_03795) | - | 737911..738255 (+) | 345 | WP_052502169.1 | minor capsid protein | - |
| NOV96_RS03800 (NOV96_03800) | - | 738255..738650 (+) | 396 | WP_024390522.1 | minor capsid protein | - |
| NOV96_RS03805 (NOV96_03805) | - | 738655..739110 (+) | 456 | WP_105204201.1 | phage tail tube protein | - |
| NOV96_RS03810 (NOV96_03810) | - | 739155..739608 (+) | 454 | Protein_722 | hypothetical protein | - |
| NOV96_RS03815 (NOV96_03815) | - | 739617..740198 (+) | 582 | WP_024390525.1 | Gp15 family bacteriophage protein | - |
| NOV96_RS03820 (NOV96_03820) | - | 740188..743463 (+) | 3276 | WP_044684419.1 | tape measure protein | - |
| NOV96_RS03825 (NOV96_03825) | - | 743463..744959 (+) | 1497 | WP_024390527.1 | distal tail protein Dit | - |
| NOV96_RS03830 (NOV96_03830) | - | 745209..746705 (+) | 1497 | WP_264687447.1 | hypothetical protein | - |
| NOV96_RS03835 (NOV96_03835) | - | 747256..747843 (+) | 588 | WP_264687448.1 | hypothetical protein | - |
| NOV96_RS03840 (NOV96_03840) | - | 747855..748034 (+) | 180 | WP_074390744.1 | hypothetical protein | - |
| NOV96_RS10985 | - | 748726..749229 (+) | 504 | Protein_729 | hypothetical protein | - |
| NOV96_RS03850 (NOV96_03850) | - | 749283..751301 (+) | 2019 | WP_407029234.1 | DUF859 family phage minor structural protein | - |
| NOV96_RS03855 (NOV96_03855) | - | 751314..751748 (+) | 435 | WP_024390530.1 | DUF1366 domain-containing protein | - |
| NOV96_RS03860 (NOV96_03860) | - | 751771..751926 (+) | 156 | WP_153308505.1 | hypothetical protein | - |
| NOV96_RS03865 (NOV96_03865) | - | 751930..752208 (+) | 279 | WP_024387693.1 | hypothetical protein | - |
| NOV96_RS03870 (NOV96_03870) | - | 752214..752456 (+) | 243 | WP_024390532.1 | phage holin | - |
| NOV96_RS03875 (NOV96_03875) | - | 752544..753906 (+) | 1363 | Protein_735 | peptidoglycan amidohydrolase family protein | - |
| NOV96_RS03880 (NOV96_03880) | - | 754077..754301 (+) | 225 | WP_264687449.1 | type II toxin-antitoxin system HicA family toxin | - |
| NOV96_RS03885 (NOV96_03885) | - | 754323..754727 (+) | 405 | WP_044673951.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| NOV96_RS03890 (NOV96_03890) | - | 754976..756190 (-) | 1215 | WP_024390438.1 | chloride channel protein | - |
| NOV96_RS03895 (NOV96_03895) | - | 756180..756458 (-) | 279 | WP_013730456.1 | chorismate mutase | - |
| NOV96_RS03900 (NOV96_03900) | rpsN | 756540..756809 (-) | 270 | WP_002940393.1 | 30S ribosomal protein S14 | - |
| NOV96_RS03905 (NOV96_03905) | - | 756950..757411 (-) | 462 | WP_012775265.1 | flavodoxin | - |
| NOV96_RS03910 (NOV96_03910) | - | 757506..758450 (+) | 945 | WP_013730455.1 | bifunctional oligoribonuclease/PAP phosphatase NrnA | - |
| NOV96_RS03915 (NOV96_03915) | - | 758437..759465 (+) | 1029 | WP_013730454.1 | FAD:protein FMN transferase | - |
| NOV96_RS03920 (NOV96_03920) | - | 759584..759826 (+) | 243 | WP_012027466.1 | type B 50S ribosomal protein L31 | - |
| NOV96_RS03925 (NOV96_03925) | - | 760112..761315 (-) | 1204 | Protein_745 | IS110-like element ISSsu7 family transposase | - |
| NOV96_RS03930 (NOV96_03930) | - | 761900..763129 (+) | 1230 | WP_012027447.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
| NOV96_RS03935 (NOV96_03935) | - | 763143..763682 (+) | 540 | WP_240016568.1 | DJ-1 family glyoxalase III | - |
| NOV96_RS03940 (NOV96_03940) | gyrB | 763864..765816 (+) | 1953 | WP_002939427.1 | DNA topoisomerase (ATP-hydrolyzing) subunit B | - |
| NOV96_RS03945 (NOV96_03945) | ezrA | 765905..767629 (+) | 1725 | WP_002935725.1 | septation ring formation regulator EzrA | - |
| NOV96_RS03950 (NOV96_03950) | serB | 767681..768316 (+) | 636 | WP_002935723.1 | phosphoserine phosphatase SerB | - |
| NOV96_RS03955 (NOV96_03955) | - | 768347..768997 (-) | 651 | WP_002935722.1 | HAD family hydrolase | - |
| NOV96_RS03960 (NOV96_03960) | - | 769105..770232 (+) | 1128 | WP_002935718.1 | glycerate kinase | - |
| NOV96_RS03965 (NOV96_03965) | - | 770223..770450 (+) | 228 | WP_002935708.1 | hypothetical protein | - |
| NOV96_RS03970 (NOV96_03970) | - | 770460..770912 (-) | 453 | WP_013730449.1 | DUF1694 domain-containing protein | - |
| NOV96_RS03975 (NOV96_03975) | eno | 771062..772369 (+) | 1308 | WP_002935704.1 | surface-displayed alpha-enolase | - |
| NOV96_RS03980 (NOV96_03980) | relB | 772679..772900 (+) | 222 | WP_012775256.1 | type II toxin-antitoxin system RelB family antitoxin | - |
| NOV96_RS03985 (NOV96_03985) | - | 772902..773162 (+) | 261 | WP_009910443.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NOV96_RS03990 (NOV96_03990) | - | 773329..773970 (+) | 642 | WP_024413325.1 | HAD family hydrolase | - |
| NOV96_RS03995 (NOV96_03995) | - | 774003..774188 (-) | 186 | WP_002935693.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 196 a.a. Molecular weight: 21494.74 Da Isoelectric Point: 5.7110
>NTDB_id=752652 NOV96_RS03545 WP_002937303.1 700375..700965(+) (clpP) [Streptococcus suis strain WUSS030]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGTAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNKLEKILADNSGK
TVKQIHKDAERDYWMSAEETLAYGFIDQIMDNTKVK
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGTAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNKLEKILADNSGK
TVKQIHKDAERDYWMSAEETLAYGFIDQIMDNTKVK
Nucleotide
Download Length: 591 bp
>NTDB_id=752652 NOV96_RS03545 WP_002937303.1 700375..700965(+) (clpP) [Streptococcus suis strain WUSS030]
ATGATTCCAGTAGTTATTGAACAAACTAGCCGTGGTGAGCGTTCTTATGATATTTACTCACGCCTTTTGAAAGACCGCAT
TATCATGTTGACAGGACCAGTTGAGGACAACATGGCAAACTCTATCATTGCACAATTGCTTTTCCTTGATGCCCAAGACC
CTACAAAGGATATTTACCTCTATGTTAATACGCCAGGAGGATCGGTGTCAGCAGGTCTTGCCATTGTAGACACGATGAAT
TTCATTAAAGCTGATGTTCAAACCATCGTTATGGGAACAGCTGCGAGCATGGGAACCATCATTGCATCAAGCGGTGCCAA
GGGCAAACGTTTCATGTTGCCAAATGCAGAGTACATGATTCACCAGCCAATGGGTGGAACTGGTGGTGGTACTCAGCAAA
CAGATATGGCTATTGCTGCAGAACACCTATTAAAAACACGTAATAAGCTAGAAAAAATCTTGGCAGACAACTCAGGTAAG
ACAGTCAAGCAAATCCACAAGGATGCAGAACGTGATTACTGGATGTCAGCTGAAGAAACCTTGGCTTATGGATTTATTGA
CCAGATTATGGACAATACAAAAGTCAAATAA
ATGATTCCAGTAGTTATTGAACAAACTAGCCGTGGTGAGCGTTCTTATGATATTTACTCACGCCTTTTGAAAGACCGCAT
TATCATGTTGACAGGACCAGTTGAGGACAACATGGCAAACTCTATCATTGCACAATTGCTTTTCCTTGATGCCCAAGACC
CTACAAAGGATATTTACCTCTATGTTAATACGCCAGGAGGATCGGTGTCAGCAGGTCTTGCCATTGTAGACACGATGAAT
TTCATTAAAGCTGATGTTCAAACCATCGTTATGGGAACAGCTGCGAGCATGGGAACCATCATTGCATCAAGCGGTGCCAA
GGGCAAACGTTTCATGTTGCCAAATGCAGAGTACATGATTCACCAGCCAATGGGTGGAACTGGTGGTGGTACTCAGCAAA
CAGATATGGCTATTGCTGCAGAACACCTATTAAAAACACGTAATAAGCTAGAAAAAATCTTGGCAGACAACTCAGGTAAG
ACAGTCAAGCAAATCCACAAGGATGCAGAACGTGATTACTGGATGTCAGCTGAAGAAACCTTGGCTTATGGATTTATTGA
CCAGATTATGGACAATACAAAAGTCAAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpP | Streptococcus pyogenes JRS4 |
92.347 |
100 |
0.923 |
| clpP | Streptococcus pyogenes MGAS315 |
92.347 |
100 |
0.923 |
| clpP | Streptococcus mutans UA159 |
90.306 |
100 |
0.903 |
| clpP | Streptococcus pneumoniae R6 |
88.776 |
100 |
0.888 |
| clpP | Streptococcus pneumoniae Rx1 |
88.776 |
100 |
0.888 |
| clpP | Streptococcus pneumoniae D39 |
88.776 |
100 |
0.888 |
| clpP | Streptococcus pneumoniae TIGR4 |
88.776 |
100 |
0.888 |
| clpP | Streptococcus thermophilus LMG 18311 |
88.776 |
100 |
0.888 |
| clpP | Streptococcus thermophilus LMD-9 |
88.776 |
100 |
0.888 |
| clpP | Lactococcus lactis subsp. lactis strain DGCC12653 |
84.184 |
100 |
0.842 |
| clpP | Lactococcus lactis subsp. cremoris KW2 |
83.673 |
100 |
0.837 |
| clpP | Bacillus subtilis subsp. subtilis str. 168 |
58.163 |
100 |
0.582 |
| clpP | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.549 |
98.469 |
0.577 |