Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CLAM6_RS03840 Genome accession   NZ_AP021868
Coordinates   894680..895918 (-) Length   412 a.a.
NCBI ID   WP_153635189.1    Uniprot ID   A0A5K7Y150
Organism   Cobetia sp. AM6     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 889680..900918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CLAM6_RS03815 (CLAM6_07400) argJ 890437..891660 (+) 1224 WP_153635186.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -
  CLAM6_RS03820 (CLAM6_07410) - 891768..892721 (+) 954 WP_043332483.1 Nudix family hydrolase -
  CLAM6_RS03825 (CLAM6_07420) yacG 892853..893098 (-) 246 WP_153635187.1 DNA gyrase inhibitor YacG -
  CLAM6_RS03830 (CLAM6_07430) coaE 893091..893741 (-) 651 WP_153635188.1 dephospho-CoA kinase -
  CLAM6_RS03835 (CLAM6_07440) pilD 893738..894598 (-) 861 WP_172978616.1 A24 family peptidase Machinery gene
  CLAM6_RS03840 (CLAM6_07450) pilC 894680..895918 (-) 1239 WP_153635189.1 type II secretion system F family protein Machinery gene
  CLAM6_RS03845 (CLAM6_07460) pilB 896093..897829 (-) 1737 WP_153635190.1 type IV-A pilus assembly ATPase PilB Machinery gene
  CLAM6_RS03850 (CLAM6_07470) - 898401..898865 (+) 465 WP_153635191.1 pilin -
  CLAM6_RS03855 (CLAM6_07480) - 898923..899225 (-) 303 WP_043332474.1 hypothetical protein -
  CLAM6_RS03860 (CLAM6_07490) - 899398..900684 (-) 1287 WP_153635192.1 cation diffusion facilitator family transporter -

Sequence

Protein


Download         Length: 412 a.a.        Molecular weight: 44988.50 Da        Isoelectric Point: 9.9207

>NTDB_id=75071 CLAM6_RS03840 WP_153635189.1 894680..895918(-) (pilC) [Cobetia sp. AM6]
MATPRTAKQDKKKAGIETWQWSGKNSRGENVKGELMSQNIDQVKSTLISQGIVVKRLRKKSSLFGGSKRVSGKDVTMFAR
QMATMIRAGVPVLQAFGIVAESMKSPGMRHLVEDLMNQVGAGASFSEALRKHPQHFDNLFTNLVAAGEQAGALDKMLDRV
ATYKEKIDSLKARVKKALYYPAAVICVGFGVTAILLIKVVPQFETLFKGFGAELPAFTQLTLKLSEYAQAYWYVAIAAII
VSIISISQGMKRSDKFAYAMHRFMLKVPVLGDILDKSSVARYSRTLATTFQAGVPLIESLDTAAGATGSKVYERAIAQIK
EDVSTGQQLNFAMRNTQLFPTLAVQMVAIGEESGSLDAMLNKVADFYEEDVDNKVDALTSLLEPFIIVVLGTLVGGLVVS
MYLPIFEMGNVM

Nucleotide


Download         Length: 1239 bp        

>NTDB_id=75071 CLAM6_RS03840 WP_153635189.1 894680..895918(-) (pilC) [Cobetia sp. AM6]
ATGGCAACTCCCAGAACTGCCAAGCAAGACAAGAAAAAAGCGGGCATTGAAACTTGGCAATGGTCGGGCAAAAACTCGCG
CGGTGAAAACGTCAAGGGCGAGCTGATGTCCCAAAATATCGATCAGGTCAAGAGCACGCTAATCAGCCAAGGGATTGTGG
TCAAGCGCCTGCGCAAGAAGTCCTCCCTGTTTGGCGGTAGCAAAAGAGTCAGTGGAAAGGACGTCACCATGTTCGCTCGC
CAGATGGCAACGATGATTCGCGCTGGCGTACCCGTATTACAGGCGTTTGGCATCGTTGCCGAGAGTATGAAAAGCCCAGG
CATGCGCCACCTGGTCGAGGATTTGATGAATCAAGTAGGAGCAGGGGCCAGCTTTTCGGAAGCCCTACGCAAGCACCCTC
AGCATTTTGATAATCTATTCACCAATCTTGTTGCTGCTGGGGAGCAGGCCGGTGCTTTAGACAAGATGCTGGACCGAGTG
GCTACATACAAAGAAAAGATAGACTCGCTCAAGGCTCGTGTAAAGAAAGCTCTATATTATCCTGCTGCCGTAATATGTGT
CGGCTTTGGTGTGACTGCCATTCTATTAATAAAAGTCGTACCGCAATTCGAAACGCTTTTCAAAGGTTTTGGAGCTGAAT
TACCAGCGTTCACTCAACTCACGTTGAAGCTTTCAGAATATGCCCAAGCATATTGGTATGTAGCCATAGCCGCTATAATC
GTTTCAATAATCTCTATTTCTCAAGGCATGAAAAGATCAGATAAATTTGCTTATGCAATGCATCGTTTTATGCTAAAAGT
TCCTGTTTTAGGAGATATACTAGACAAATCTTCTGTCGCAAGATACTCCAGAACGCTAGCCACCACCTTCCAAGCAGGCG
TGCCGCTGATAGAGTCATTGGACACCGCAGCTGGCGCTACAGGTAGTAAAGTCTATGAACGCGCGATCGCCCAGATAAAA
GAAGATGTTTCTACAGGCCAGCAGCTAAATTTTGCCATGCGTAACACTCAGTTGTTTCCGACATTGGCAGTACAGATGGT
GGCGATTGGTGAAGAATCGGGCTCCTTGGATGCCATGCTCAACAAGGTCGCTGACTTCTATGAAGAGGATGTCGATAACA
AGGTAGATGCACTAACCTCGCTACTGGAACCCTTTATTATTGTAGTATTAGGCACACTTGTCGGAGGTCTGGTTGTCTCA
ATGTACTTGCCAATTTTCGAAATGGGCAACGTCATGTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(78-201)

Type II secretion system (T2SS), protein F (T2SSF)

(283-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5K7Y150

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.962

95.874

0.546
  pilC Acinetobacter baylyi ADP1

53.086

98.301

0.522
  pilC Acinetobacter baumannii D1279779

52.84

98.301

0.519
  pilC Legionella pneumophila strain ERS1305867

50.372

97.816

0.493
  pilC Vibrio cholerae strain A1552

45.363

96.845

0.439
  pilC Vibrio campbellii strain DS40M4

45

97.087

0.437
  pilG Neisseria meningitidis 44/76-A

40.686

99.029

0.403
  pilG Neisseria gonorrhoeae MS11

40.686

99.029

0.403

Multiple sequence alignment