Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   QMM28_RS10605 Genome accession   NZ_AP019757
Coordinates   1902539..1903465 (+) Length   308 a.a.
NCBI ID   WP_040948034.1    Uniprot ID   -
Organism   Coxiella burnetii strain 406     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1897539..1908465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMM28_RS10560 (CBU406_C19130) - 1898131..1898403 (-) 273 WP_099140165.1 hypothetical protein -
  QMM28_RS10565 - 1898369..1898485 (-) 117 Protein_2057 hypothetical protein -
  QMM28_RS10570 (CBU406_C19140) - 1898594..1898848 (+) 255 WP_005769716.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
  QMM28_RS10575 (CBU406_C19150) - 1898848..1899123 (+) 276 WP_005769718.1 Txe/YoeB family addiction module toxin -
  QMM28_RS10580 (CBU406_C19160) - 1899096..1899581 (-) 486 WP_005769725.1 dihydrofolate reductase -
  QMM28_RS10585 (CBU406_C19170) - 1899578..1900381 (-) 804 WP_017253341.1 epoxyqueuosine reductase QueH -
  QMM28_RS10590 (CBU406_C19180) - 1900577..1900864 (+) 288 WP_005769730.1 acylphosphatase -
  QMM28_RS10595 (CBU406_C19190) gmhB 1900840..1901394 (-) 555 WP_005769732.1 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase -
  QMM28_RS10600 (CBU406_C19200) fmt 1901407..1902351 (-) 945 WP_010958586.1 methionyl-tRNA formyltransferase -
  QMM28_RS10605 (CBU406_C19210) dprA 1902539..1903465 (+) 927 WP_040948034.1 DNA-processing protein DprA Machinery gene
  QMM28_RS10610 (CBU406_C19220) - 1903462..1903941 (+) 480 WP_010958588.1 DUF494 domain-containing protein -
  QMM28_RS10615 (CBU406_C19230) topA 1903944..1906241 (+) 2298 WP_040948035.1 type I DNA topoisomerase -
  QMM28_RS10620 (CBU406_C19240) - 1906248..1906418 (-) 171 WP_010958590.1 hypothetical protein -
  QMM28_RS10625 (CBU406_C19250) purE 1906449..1906949 (+) 501 WP_005769750.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  QMM28_RS10630 (CBU406_C19260) - 1906952..1907512 (+) 561 WP_012220042.1 L-threonylcarbamoyladenylate synthase -
  QMM28_RS10635 (CBU406_C19270) - 1907963..1908103 (+) 141 WP_010958591.1 hypothetical protein -

Sequence

Protein


Download         Length: 308 a.a.        Molecular weight: 33077.35 Da        Isoelectric Point: 7.8929

>NTDB_id=73871 QMM28_RS10605 WP_040948034.1 1902539..1903465(+) (dprA) [Coxiella burnetii strain 406]
MQPPFNALLFFAMPNSQLDPEWTTAPNHHILTLDHPSYPTLLKEIPDPPKKLYIMGDPLILNQPQFAIVGSRNPTVTGCE
IAQEMAEKLVQAGFHITSGLALGIDAASHRGALKAGGQTIAVLGSGLTNIYPRRHHRLAEQISQKGALVSEFPLTMPPLP
TNFPRRNRIIIGLSLGTLVVEATLGSGSLITAKLAAEQNREVFAIPGSIRNPLSQGCHALIKEGAKLVDSIGDIIAELSY
EATGASAPIQALDKNEHKLLECIGFEVTSIDQLIARSGFSASIVASLLLRIELQGYIKSRPGGVIRVK

Nucleotide


Download         Length: 927 bp        

>NTDB_id=73871 QMM28_RS10605 WP_040948034.1 1902539..1903465(+) (dprA) [Coxiella burnetii strain 406]
TTGCAACCTCCCTTCAATGCACTATTATTTTTCGCCATGCCAAATTCTCAATTAGACCCAGAATGGACGACAGCGCCGAA
CCACCATATTTTGACGCTCGATCATCCCTCCTACCCTACTTTATTGAAGGAAATCCCCGATCCGCCCAAAAAGCTCTACA
TCATGGGTGACCCTTTGATATTAAATCAGCCGCAATTTGCCATCGTCGGCAGCCGTAATCCAACCGTCACCGGCTGCGAA
ATCGCACAAGAAATGGCAGAGAAACTCGTTCAAGCTGGTTTTCACATCACCAGCGGCCTTGCACTTGGCATCGATGCCGC
AAGTCACCGCGGGGCTTTAAAAGCAGGAGGCCAAACCATAGCCGTACTCGGCAGCGGCTTAACTAACATATATCCTCGAC
GCCACCACCGTCTGGCGGAACAAATTTCCCAAAAAGGCGCCCTCGTCTCAGAATTCCCGCTAACCATGCCGCCACTCCCC
ACCAACTTCCCTCGCCGCAACCGCATCATCATCGGATTAAGCCTCGGTACGCTCGTGGTGGAAGCTACCCTTGGCTCAGG
CTCTCTGATCACCGCGAAATTAGCCGCCGAACAAAACCGGGAAGTTTTCGCCATCCCGGGTTCAATCCGAAACCCTCTTT
CTCAGGGATGCCATGCTCTCATCAAAGAGGGCGCTAAACTGGTTGATTCTATAGGGGATATTATTGCAGAATTGAGTTAT
GAGGCTACGGGCGCTAGCGCCCCGATTCAAGCACTTGATAAGAATGAACACAAACTGTTAGAGTGCATCGGATTTGAGGT
CACTTCCATTGATCAACTGATCGCTCGAAGTGGCTTTTCGGCTTCCATCGTAGCTTCGTTATTGTTAAGGATAGAATTGC
AAGGCTACATTAAATCAAGACCTGGCGGTGTTATACGAGTGAAGTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(25-229)

DprA winged helix domain (DprA_WH)

(245-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Legionella pneumophila strain ERS1305867

54.266

95.13

0.516
  dprA Vibrio cholerae strain A1552

48.829

97.078

0.474
  dprA Vibrio campbellii strain DS40M4

47.386

99.351

0.471
  dprA Glaesserella parasuis strain SC1401

44.951

99.675

0.448
  dprA Acinetobacter baumannii D1279779

44.369

95.13

0.422
  dprA Acinetobacter baumannii strain A118

43.878

95.455

0.419
  dprA Acinetobacter baylyi ADP1

42.712

95.779

0.409
  dprA Haemophilus influenzae Rd KW20

55.046

70.779

0.39

Multiple sequence alignment